A drive mechanism for a medicament delivery device is presented having a base member with a guide track structure that includes a first track, a second track, a rotator base member having a first guide structure that runs in the first track, a rotator housing coaxially arranged with and configured to engage with the rotator base member, the rotator housing having a second guide structure arranged at a fixed distance from the first guide structure and configured to run in the second track, a rotation device configured to actuate the rotator housing, and a medicament container carrier configured to receive a medicament container, wherein the medicament container carrier is coaxially arranged relative to the rotator base member and the rotator housing, the rotator housing being configured to rotate relative to the medicament container carrier.

The present invention provides a drug injection device (100) comprising a first element (140) and a second element (103) configured to undergo unidirectional movement relative to each other corresponding to an action performed on or by the drug injection device (100), wherein the first element (140) comprises a plurality of serially disposed protrusions (143), wherein the second element (103) comprises first and second deflectable transducers (103a/153a, 103b/153b) configured for sequentially cooperating with the plurality of protrusions (143), and wherein a processor (151) is electrically connected with the first and second deflectable transducers (103a/153a, 103b/153b) to register activation signals, wherein the protrusion configuration is so disposed on the first element (140) and the first and second deflectable transducers (103a/153a, 103b/153b) are so disposed on the second element (103) that a second activation signal generated by the second deflectable transducer (103b/153b) is delayed relative to a first activation signal generated by the first deflectable transducer (103a/153a) as the first element (140) and the second element (103) move relative to each other, and wherein the processor (151) is configured to provide a) a first control action if a time delay between the first and second activation signals is above or equal to a pre-defined value, and b) a second control action if said time delay is below said pre-defined value.

An optical decoding system including an optical sensor integral with or attachable to a housing of a drug delivery device and configured to be directed at first and second rotatable components of a dose setting and dispensing mechanism of the drug delivery device and a processor configured to: (i) cause the optical sensor to capture images of the first and second rotatable components at least at the beginning and end of a medicament dose dispensing process; (ii) determine a rotational position of both the first and second rotatable components in each of the captured images; and (iii) determine from the rotational positions of the first and second rotatable components an amount of medicament delivered by the dose setting and dispensing mechanism of the drug delivery device.

A method of verifying that a first unit and a second unit being mounted to each other are correctly paired, the first unit comprising a first visual identifier and the second unit comprising a second visual identifier, the method comprising the steps of (i) capturing an image of the first and second unit mounted to each, the image comprising both the first and the second visual identifier, and (ii) processing the captured image to (a) identify the first and the second visual identifier, and (b) determine whether the captured identifiers represent a predefined combination of visual identifiers to thereby verify the pairing.

A unilaterally driven drug infusion device with multiple infusion modes includes a reservoir, a piston, a screw, a driving unit, at least one driving wheel provided with teeth, a linear actuator, a reset unit, and a control unit. The piston is arranged in the reservoir. The driving unit includes a rotating shaft and a driving member, and the driving member includes a driving end. The linear actuator and the reset unit are respectively connected to the driving member. The control unit controls the linear actuator or the reset unit to apply different driving powers on the driving member to make the driving member have a variety of different operating modes.

A computerized electro-mechanical drug delivery device configured to deliver at least one dose of two or more medicaments. The device comprises a control unit. An electro-mechanical drive unit is operably coupled to the control unit and a primary reservoir for a first medicament and a secondary reservoir for a fluid agent, e.g. a second medicament. An operator interface is in communication with the control unit. A single dispense assembly is configured for fluid communication with the primary and the secondary reservoir. Activation of the operator panel sets a first dose from the primary reservoir and based on the first dose and a therapeutic dose profile, the control unit is configured to determine a dose or range of the fluid agent. Alternatively, the control unit determines or calculates a dose or range of a third medicament. Further, a dispense interface for use with a drug delivery device is disclosed.

A non-slip dose delivery mechanism includes a housing, a non-rotating piston rod, a nut, a piston rod guide, a driver, a ratchet and a brake. The non-rotating piston rod has a threaded outer surface. The nut includes an inner surface in threaded engagement with the threaded outer surface of the non-rotating piston rod. The nut is configured to rotate and translate axially in a proximal direction relative to the non-rotating piston rod during dose setting. The piston rod guide is rotationally fixed relative to the housing and is configured to prevent rotation of the piston rod. The driver includes an inner surface and an outer surface, the inner surface being in a rotationally fixed engagement with the nut. The ratchet is rotationally fixed to relative to the housing. The brake is positioned between the nut and the ratchet.

Disclosed herein are devices and methods for delivering a predetermined volume of a drug substance or other product including a fluid. An exemplary device may include a body configured to receive a drug substance therein, and a plunger rod disposed at least partially inside the body to distally move a stopper in the body. The device may include a component configured to regulate distal movement of the plunger rod in a priming step and in a subsequent delivery step, so that the device may be accurately primed and may accurately dispense a predetermined volume of a drug substance.

The present disclosure relates to a medicament injection device (1) comprising a housing (3) arranged to receive a medicament container (11a), a needle cover (9) movable relative to the housing (3), from a retracted position, in which it engages the housing (3) and enables medicament delivery, to an extended position, a plunger rod (7), and a plunger driver (5) movable relative to the housing (3) from all initial position to a final position, and arranged to actuate the plunger rod (7), wherein the plunger rod (7) has a first guide arrangement and the housing (3) has a second guide arrangement, the first guide arrangement (7d) and the second guide arrangement being arranged to cooperate to guide movement of the plunger rod (7) relative to the housing (3), wherein the first guide arrangement and the second guide arrangement in a first stage provide a linear motion path for the plunger rod (7), enabling the plunger rod (7) to initially move in the axial direction and in a second stage provide a rotation motion path for the plunger rod (7), enabling the plunger rod (7) to rotate relative to the housing (3) to release the plunger rod (7) from the plunger driver (5), whereby the plunger driver (5) attains a released state enabling movement of the plunger driver (5) to its final position, wherein in the released state the plunger driver (5) is arranged to release the needle cover (9) from the housing (3) and to actuate the needle cover (9) to its extended position.

An injection device comprises a housing having a longitudinal axis, an axially-depressible dose button (430), a dose indicator (418), a dose setting mechanism operatively coupled to said dose indicator and capable of setting a dose to be ejected from the injection device and spring capable of storing energy necessary for ejecting the dose from the injection device. The spring (420) is coupled to the dose setting mechanism such that a charging force can be transferred from the dose setting mechanism to the spring to increase the energy stored by the spring. The dose setting mechanism comprises an assembly of three components, including: •a ratchet ring (410) rotationally and axially locked with respect to said housing, the ratchet ring including a ratchet component; •a drive plate (405) including a first set of splines forming a ratchet arrangement with said ratchet component; and•a dose selector (416) capable of being rotated about said longitudinal axis with respect to said housing to set the dose and including splines for disengaging said ratchet arrangement. The ratchet component is capable of interacting with both the splines on the dose selector and the splines on the drive plate.