A syringe with passive needle protection for administering a medicament dose to a patient, comprising a hollow body forming the syringe housing and containing the medicament active substance, at the distal end of which a hollow needle provided for injection of the active substance is mounted in a bearing sleeve, and in which a displaceable plunger provided at the end with a receiving hole for the hollow needle is arranged, for the most complete possible delivery of medicament while avoiding undelivered medicament residues. For this purpose, the piston is designed in several parts; in addition to a needle holder having a retaining clip for the hollow needle, it comprises a piston jacket which is shaped such that, when the needle holder is inserted, it leaves free inflow channels into the enclosed end of the hollow needle for the active substance on both sides of the retaining clip.

An autoinjector is described that includes an outer body, a first trigger, an output needle, and a first compartment. The first compartment is positioned within the outer body and includes (i) a main body, (ii) a first biasing member coupled to the first trigger, and (iii) a protrusion positioned at a distal end of the main body. The autoinjector further includes a second compartment positioned in the outer body and in fluid communication with the first compartment and the output needle. The autoinjector also includes a second biasing member coupled to a second trigger. The first biasing member is configured to, upon application of force to the first trigger, automatically move an ampule in a distal direction relative to the main body to force the ampule against the protrusion, so as to break the ampule and allow a medicament to flow from the ampule to the second compartment.

This disclosure relates to auto-injectors and their method of use with pre-filled syringes. The embodiments include an auto-injector system for injecting various solution volumes, including: an auto-injector housing having an actuating end and an injection end, the housing including; a release mechanism co-axially aligned in the housing near the actuating end; a spring co-axially aligned and in contact with the release mechanism; a pre-filled syringe co-axially aligned in the housing at the injection end, including a set capacity syringe barrel having a syringe chamber for holding a plunger cap with a plunger cap length and a solution volume for injecting, wherein the plunger cap retains the solution volume within the syringe chamber; and a syringe needle attached to the syringe barrel for injecting the solution volume; an interchangeable plunger rod that’s interchangeable having a defined interchangeable plunger rod length and being co-axially aligned in the housing between the spring and the plunger cap; and an interchangeable plunger rod extension that’s interchangeable having a defined interchangeable plunger rod extension length and being coaxially aligned and contacting the interchangeable plunger rod, wherein the lengths of the spring, interchangeable plunger rod, interchangeable plunger rod extension, and plunger cap define a co-axially aligned and continuous auto-injector system for injecting various solution volumes; and an optional auto-injector cap for covering the auto-injector housing at the injection end. The embodiments further provide methods for injecting various solution volumes using an auto-injector system, including: providing an auto-injector system for injecting various solution volumes, including an auto-injector housing having an actuating end and an injection end, the housing including a release mechanism co-axially aligned in the housing near the actuating end; a spring co-axially aligned and in contact with the release mechanism; a pre-filled syringe co-axially aligned in the housing at the injection end, including a set capacity syringe barrel having a syringe chamber for holding a plunger cap with a plunger cap length and a solution volume, wherein the plunger cap retains the solution volume within the syringe chamber; and a syringe needle attached to the syringe barrel for injecting the solution volume; an interchangeable plunger rod having a defined interchangeable plunger rod length and being co-axially aligned in the housing between the spring and the plunger cap; and an interchangeable plunger rod extension having a defined interchangeable plunger rod extension length and being co-axially aligned and contacting the i

An assembly (47) for a medication delivery device (1) has a body (2), a dose setting part (8) configured to be operated by a user for selecting a size of a dose, a piston rod (13) configured to be moved axially without rotating for dispensing a medication, and a drive member (12) being directly coupled to the piston rod (13) for driving the piston rod (13) in a dose dispensing operation, wherein the drive member (12) moves in a proximal direction in a dose setting operation. The medication delivery device (1) into which the assembly is incorporated may be a single-shot, variable-dose injection device, e.g., a syringe.

An injection device (10) comprises an injection solution receptacle (30) and a plunger (70) at feast a portion of which is slidably received in the injection solution receptacle (30), wherein the plunger (70) is displaceable relative to the injection solution receptacle (30) in a distal direction in order to expel an injection solution contained in the injection solution receptacle (30) from the injection solution receptacle (30). A first plunger stop mechanism (140) is adapted to stop a displacement of the plunger (70) relative to the injection solution receptacle (30) in the distal direction at a first dosing position (P1). A second plunger stop mechanism (140) is adapted to stop a displacement of the plunger (70) relative to the injection solution receptacle (30) from the first: dosing position (P1) in the distal direction at a second dosing position (P2), wherein the first and the second dosing position (P2) of the plunger (70) are selected in such a manner that the plunger (70), upon being displaced relative to the injection solution receptacle (30) between the first and the second dosing position (P2) is adapted to expel a desired dose of the injection solution contained in the injection solution receptacle (30) from the injection solution receptacle (30).

A device for injecting a medicament is provided. The device has a housing with a container within it which can hold a medicament. At its proximal end the container has a needle and a stopper. The device includes a plunger which at one end can engage the stopper. At the opposite end, the plunger can engage a first resilient member to move the stopper within the container to inject the medicament from the container. The device includes a collar with distal and proximal ends, the distal end engaging with a carriage and causing its rotation and the proximal end engaging with a second resilient member. The second resilient member can engage with a skin sensor which has distal and proximal ends. At the proximal end, the skin sensor can contact an injection site. The housing has a cap which can reduce or prevent movement of the skin sensor.

A lockable syringe, which includes a syringe body having a longitudinal axis and including a distal end and a proximal end, and a locking mechanism, wherein the locking mechanism is configured to be attached to the proximal end of the syringe body. The locking mechanism includes: a plunger having at least one distal plate, and a rod with visual elements for marking an unlock position; and a locking ring which is free in its rotation about the longitudinal axis of the syringe body, the locking ring has at least two visual indicators on its outer surface, and the locking ring has elements for blocking the plunger stroke in a locked position.

A syringe with needle protection with a plunger displaceable by means of an actuating plunger in the interior of a syringe body is designed for particularly effective delivery of the active substance with the lowest possible residual portion in the syringe that is not delivered. For this purpose, the plunger has a needle holder for receiving the syringe needle, the needle bearing of which is arranged on a retaining bracket, leaving a number of lateral inflow surfaces free.

The dose setting assembly for a medical injection device including a barrel defining a reservoir adapted to contain a medical injection fluid, an open proximal end and a distal end including a hub portion, a flange disposed at the proximal end of said barrel, and an elongated plunger rod having a plunger flange at a proximal end and a stopper a distal end. The plunger rod being able to slidably move within the barrel, includes a backstop attachable to the flange of the barrel and a dose setting member secured on the backstop, configured to maintain the plunger rod in a predetermined position, the dose setting member being transversally removable from the backstop to authorize the plunger rod to move towards the backstop and abuts onto said backstop.

A device for administering a liquid to a human by means of injection of liquid. The device is configured with a movement device arranged to move a gripping element for gripping an injector. The injector is adapted with an individual dose of the liquid and an injection needle and preferably comprises a housing and an operating member to expel the liquid from the injector via the injection needle. The gripping element includes a first component for engaging the housing and a second component for operating an operating member. The first component and the second component are resistively slidable relative to each other, and the first component is connected to the movement device via the second component.