An injection device for delivering a dose from a cartridge or syringe. The injection device comprises a housing, a drive shaft, a drive spring for urging the drive shaft to rotate relative to the housing, and a plunger coupled to the drive shaft such that rotation of the drive shaft relative to the housing causes the plunger to move axially relative to the housing. The device further comprises a dose setting member moveable relative to the drive member between a first position in which the dose setting member is rotatable relative to the housing for setting a dose and a second position in which the dose setting member is rotationally fixed relative to the housing for delivering a dose, and a stop member. The stop member is engaged between the dose setting member and the drive shaft such that relative rotation between the dose setting member and the drive shaft during dose setting causes the stop member to travel relative to a first stop surface, and rotation of the dose setting member together with the drive shaft during dose delivery does not cause the first stop member to travel relative to the first stop surface. If the stop member abuts the first stop surface during relative rotation between the dose setting member and the drive shaft, continued travel of the stop member and hence continued relative rotation between the dose setting member and the drive shaft is prevented.

Disclosed herein are delivery devices for delivering a volume of a drug product, placebo product, or other product including a fluid. The devices may include a barrel having a longitudinal axis, a proximal end region, and a distal end region. The proximal end region may include an opening, and the barrel may be configured to receive a drug therein. A plunger rod may be disposed at least partially inside the barrel and protruding from the opening. The plunger rod may include a rack having a plurality of teeth. The device may further include a pinion having a plurality of teeth configured to engage with the plurality of teeth of the rack, and rotation of the pinion against the rack may move at least a part of the plunger rod along the longitudinal axis of the barrel.

A device for administering a fluid can include a cylinder, a piston connected to a piston rod, and a tensioning device connected to the piston rod. In a dispensing procedure, a ramp track is rotated until a roller runs over a transfer region and is accelerated toward the first plateau and, as a result, the piston is moved toward an open dispensing end. The ramp track runs on the face side of a wall extending along a circular path. A cover engages over the ramp track, the driver and the roller and has at least one scraper extending counter to the first direction and extending within the wall as far as the inner side of the wall, and thus scrapes off lubricant located on the inner side from the inner side.

The techniques described herein relate to computerized methods and apparatus for determining a dose injected into a user by one or more medication delivery devices. Data is accessed that is indicative of an injection event group that includes one or more injection events associated with one or more medication delivery devices. The injection event group is processed to determine the dose injected into the user based on one or more of whether the injection event is associated with a medication delivery device change, a dose size of one or more of the injection events, a position of one or more of the injection events in the injection event group, and/or a time period between one or more injection events to a next injection event in the injection event group.

The present invention relates to a handheld mechanical injection device by which set doses of a liquid medicament can be injected from a medical reservoir. The medicament is expelled through an injection needle by release of a power reservoir in the device, the power reservoir being fully or partially released by actuation of a user operable release member being positioned at or near an upper end of the injection device, the upper end being that end of the injection device which is opposite the injection needle.

An actuation mechanism is presented for a medicament delivery device having a plunger rod arranged to act on a stopper of a medicament container, an actuator arranged slidable and connected to the plunger rod for acting on the stopper when said actuator is operated by displacing it in a longitudinal direction of the actuation mechanism, and an activator for activating the actuation mechanism and for setting a dose. The activator having a generally tubular activator sleeve provided with a spirally extending groove on an outer surface, the groove arranged with a length corresponding to the total amount of medicament to be delivered in a number of doses contained in said medicament container, where the groove is provided with an end wall, a stop ring arranged coaxial with said activator sleeve. The activator sleeve arranged with a follower positioned in the groove and the follower arranged to abut the end wall when the total amount has been delivered.

The present invention provides a drug injection device (1) for delivering multiple doses of drug, comprising: a housing (2) extending along a main axis, a dose expelling mechanism comprising a piston rod (60) configured to move relative to the housing (2) from a first position to a second position to cause ejection of a dose of drug, the piston rod (60) extending between a proximal piston rod end and a distal piston rod end and comprising a dosing track (63), the piston rod (60) further being movable relative to the housing (2) from an initial pre-use position to a final end stop position to cause accumulated ejection of a predefined total dose, a dosing track follower (17) fixed with respect to the housing (2) and adapted to travel the dosing track (63) during dose ejection, a dose setting mechanism operable to set the dose to be ejected by the dose expelling mechanism, electronic means (82, 90, 91, 92, 95) for registering a dose setting operation and for registering a dose size of an ejected dose, and a display (81) adapted to indicate a size of a current set dose, the electronic means (82, 90, 91, 92, 95) being configured to provide a first type of update of the display (81) responsive to dose changing operations of the dose setting mechanism, wherein the electronic means (82, 90, 91, 92, 95) is further configured to calculate a current accumulated dose from the dose sizes of registered ejected doses to thereby provide an updated value of a total amount of drug ejected, determine a current remaining dose by comparing the current accumulated dose and the predefined total dose, and provide a second type of update of the display (81) when during a dose increasing operation of the dose setting mechanism the current set dose exceeds the current remaining dose, the second type of update being different from the first type of update, and wherein the final end stop position is defined by a track end configuration of the dosing track (63) between the proximal piston rod end and the distal piston rod end.

The present invention relates to a medicament delivery device (10) comprising a housing (12, 14); a medicament container holder (90), arranged movable in relation to said housing (12, 14) and capable of accommodating a medicament container (92); an biased activator (160) comprising a plunger rod (164), which plunger rod (164) is arranged to act on the medicament container (92) for delivering a dose of medicament through a medicament delivery member (102 when said biased activator (160) is operated; a manually operable dose setting member (72) operably connected to both said housing and said medicament container holder such that manual operation of said dose setting member (72) will cause the medicament container holder (90) with the medicament container (92) to move towards said plunger rod (164) for setting a dose of medicament to be delivered; a dose drum (56) releasably connected to the dose setting member (72) through a releasable connection mechanism (68, 84I) such that when the dose setting member is operated, said dose drum (56) is displaced from an initial position to a set dose position; a release mechanism (116) operably connected to said biased activator (160), wherein, when said plunger rod (164) is moved to an end position of the dose delivery operation, said release mechanism (116) is arranged to act on said connection mechanism (68, 84I) for releasing said dose drum (56) from said dose setting member (72). The invention is characterised in that said release mechanism is arranged with a locking mechanism (130, 84II) arranged to lock said dose setting member (72) from displacement as the connection mechanism (68, 84I) is operated for releasing said dose drum (56) from said dose setting member (72).

An example injector includes a rotary knob for selecting a function and setting a dosing quantity for an injection, a button located on an end of the rotary knob for initiating the injection, an electric motor, an encoder for evaluating output rotary motion of the motor, and a processor that converts the dosing quantity into a number of encoder pulses and controls operation of the motor based on the number of encoder pulses when dosage is triggered. The injector also includes a transmission coupled to the electric motor to convert a speed of the motor, a threaded spindle coupled to the transmission that moves linearly based on the output rotary motion of the motor at the speed as converted by the transmission, and a punch connected to an end of the threaded spindle. The linear movement of the spindle causes the punch to release medicament.

The present disclosure is directed to a dose setting mechanism that may be used with a drug delivery device. The dose setting mechanism may include an inner body having a helical thread along an outer cylindrical surface of the inner body, and a drive sleeve for driving a piston rod in an axial direction, the drive sleeve positioned within at least a portion of the inner body. The dose setting mechanism may further include a dose dial sleeve rotatably engaged with the helical thread of the inner body and a dial grip connected to the dose dial sleeve and releasably connected to the drive sleeve. Further when a dose is set, the dial grip is rotated so that both the dose dial sleeve and the drive sleeve rotate with respect to the inner body.