The present disclosure is generally directed to a resettable drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The drug delivery device comprises a housing, a cartridge holder, releasably attached to the distal end of the housing, a piston rod, engaging a housing insert and a drive member, a dose setting member, guided within the housing to allow rotation of the dose setting member during dose setting and dose dispensing, and a clutch for rotationally coupling the drive member and the dose setting member. The housing insert is rotationally constrained to the housing and is axially movable together with the drive member relative to the housing between a dose setting and dispensing position, and a resetting position. In the dose resetting position, the drive member is rotationally de-coupled from the housing.

An injection device having a drive member with first and second gear patterns that are fixed relative to each other. The drive member is rotatable and translatable in first and second opposing axial directions. A plunger expels medicament from a cartridge when it is translated in an advancing direction. A dosage indicator indicates a set dosage. A first gearing arrangement operably couples the first gear pattern with the plunger wherein rotation of the drive member in a first direction translates the drive member in a first axial direction without movement of the plunger and translation of the drive member in the opposite axial direction drives the plunger in the advancing direction. A second gearing arrangement operably couples the second gear pattern with the dosage indicator and moves the dosage indicator to indicate an increase in the set dosage when the drive member is translated in the first axial direction.

Implementations of the present disclosure are directed to an injection device including: a reservoir including a wall defining a proximal end, a distal end and a tubular side, a plunger rod configured to be movable within the reservoir in a direction from the distal end to the proximal end, a radio frequency (RF) antenna attached to the tubular side and configured to receive an interrogation signal from an external device, and a resonating assembly configured to receive the interrogation signal from the RF antenna and to generate a modulated RF signal having a frequency associated with a position of the plunger rod.

A drive mechanism for a medicament delivery device is presented having an activation rod provided with external activation rod threads having a first thread helix angle, an activation knob rotationally locked with the activation rod, wherein the activation knob is configured to be moved between a first axial position relative to the activation rod in which the activation knob is prevented from rotation and a second axial position in which the activation knob is allowed to rotate in a first direction, an axially slidable drum which is rotationally locked, a dose drum rotationally locked relative to the activation rod, wherein the dose drum is configured to rotate relative to the slidable drum, an indicator drum provided with external indicator drum threads having a second thread helix angle, wherein rotation of the activation knob in the first direction causes concurrent first rotation of the activation rod and the dose drum in accordance with the first thread helix angle.

Implementations of the present disclosure are directed to an injection device including: a reservoir including a wall defining a proximal end, a distal end and a tubular side, a plunger rod configured to be movable within the reservoir in a direction from the distal end to the proximal end, a radio frequency (RF) antenna attached to the tubular side and configured to receive an interrogation signal from an external device, and a resonating assembly configured to receive the interrogation signal from the RF antenna and to generate a modulated RF signal having a frequency associated with a position of the plunger rod.

Injection monitoring module removably mountable to a proximal extremity of an injection pen comprising a pen body, a proximally located dose setting wheel, and an injection activator, the dose setting wheel rotating about a central longitudinal axis of the pen during dose setting, the injection monitoring module comprising a hollow main body coaxially mounted on, and engaging in co-rotation with the dose setting wheel, the main body comprising a longitudinal bore having a proximal and distal extremities, and a central longitudinal axis; one or more magnets located on or within the main body; an injection monitoring system comprising at least one magnetic sensor movable in translation along the central axis within the bore, from a first monitoring position, to a second monitoring position; the injection monitoring module further comprising a rotational stop means preventing rotational movement of the monitoring system about the central axis during dose selection.

An injection device for setting and injecting a dose of a medicament comprises a housing) extending along an axial direction (z), a dose setting mechanism arranged in the housing, a dose dial displaceable relative to the housing for setting of the dose, a dose tracker (50; 150) operably connectable to the dose dial (12), the dose tracker is at least one of translationally or rotationally displaceable relative to the housing during setting of a dose, wherein a positional state of the dose tracker relative to the housing is indicative of a size of the dose, and a preselector configured to define a maximum dose positional state of the dose tracker relative to the housing, and a first marker provided on one of the dose tracker and the preselector and configured to indicate the positional state of the dose tracker relative to the preselector.

Described is a dose tracking mechanism for a drug delivery device, including an RFID device with an electric circuit and a switch operable to open and close the electric circuit to transmit a wireless signal to a receiving device when the electric circuit is closed by the switch. The switch is configured to open and close in response to operation of a dose setting and/or a dose dispensing mechanism of the drug delivery device, and the closing and opening of the electric circuit generates a pulse of the wireless RFID signal. In one embodiment, each pulse corresponds to a unit of a dose of medicament set by the dose setting mechanism or dispensed by the dose dispensing mechanism from a drug container of the drug delivery device, depending on if the dose setting or dose dispensing mechanism is arranged to toggle the switch.

An injection device comprises a housing with a receptacle for a product, a dosing mechanism for setting a product dosage to be administered and for displaying the product dosage that has been set, and a dispensing mechanism for dispensing the product. The dosing mechanism comprises a dosing sleeve which is rotatable relative to the housing in a first direction for setting a product dosage and which is rotatable relative to the housing in a second, opposite direction for correcting or dispensing a product dosage. The dispensing mechanism comprises a piston rod, at least one sleeve, and a clutch. The device further comprises a first detector for detecting movement of the clutch relative to the dosing sleeve and/or the housing and/or the at least one sleeve and a data processing unit connected to the first detector for reading, storing, processing, transmitting, and/or displaying signals received from the first detector.

A device for administering a fluid is provided, with a cylinder (16, 116) which has an open dispensing end (17), a piston (36) which is displaceable between a front and rear end position in the cylinder (16, 116) and is connected to a piston rod (35) that protrudes along a first direction beyond a rear end of the cylinder (16, 116) opposite the open dispensing end (17) and is guided in a receiving block (10), a nonreturn valve (18) closing the open dispensing end (17), and a tensioning device (S) which is connected to the piston rod (35, 135) and is arranged in the receiving block (10), wherein the tensioning device (S), when the piston (36) is in its front end position, can move the piston rod (35, 135) in a tensioning operation along the first direction until the piston (36) is in its rear end position in order thereby to fill the cylinder (16, 116) with the fluid to be administered and in order to pretension the piston rod (35, 135) toward the open dispensing end (17), and wherein the tensioning device (S), when the piston (36) is in its rear end position, can release the piston rod (35, 135) in a dispensing operation, and therefore the piston (36) moves counter to the first direction as far as its front end position because of the applied pretension and, in the process, fluid in the cylinder (16, 116) is dispensed via the nonreturn valve (18) for administering, wherein the receiving block (10) is in the form of an integral receiving block (10) which is produced by an additive production method.