A medicament delivery device may comprise a medicament chamber configured to hold a medicament, a plunger configured to move relative to the medicament chamber to expel the medicament from the medicament chamber, a pin configured to move from a first pin position wherein the pin prevents movement of the plunger to a second pin position wherein the pin allows movement of the plunger, an actuation assembly configured to move the pin from the first pin position to the second pin position, and a needle coupled to the medicament chamber. The medicament may flow through the needle from the medicament chamber to a user. The actuation assembly may be configured to automatically move the pin after a predetermined time delay.

The present disclosure relates to a medicament delivery device comprising a housing, a reservoir for medicament disposed in the housing and a dispensing member. The dispensing member is moveable relative to the housing from a first position to a second position to dispense medicament from the reservoir when the reservoir contains medicament. The medicament delivery device further comprises first and second biasing members. The first biasing member is configured to urge the dispensing member from the first position to an intermediate position. The second biasing member is configured to urge the dispensing member from the intermediate position to the second position.

A system for mixing drug products and injecting includes a syringe body, proximal and distal stopper members disposed in the syringe body, a plunger member, and a needle hub assembly coupled to the distal needle interface of the syringe body. The proximal and distal stopper members form a proximal drug chamber between there between and a distal drug chamber between the distal stopper member and a distal end of the syringe body. The plunger member includes a needle retention feature, an energy-storage member, and an energy-storage member latching member all disposed in disposed in a plunger interior. First and second sizes of the respective proximal and distal drug chambers can be modified by movement of the proximal and distal stopper members relative to the syringe body. The needle is at least partially retractable into plunger interior upon manipulation of the plunger member relative to the syringe body.

An injection apparatus for injecting a medicament into a patient, the injection apparatus has a stationary head and a movable head that is movable with respect to the stationary head. A needle is attached to a needle holder that is held by the movable head and by the stationary head. When the movable head is urged rearwardly, a front edge of the needle moves forwardly with respect to a front face of the movable head.

A medical instrument that includes a needle and an expandable member located at a distal end of the needle. The expandable member includes a blocking member. The expandable member is configured to move tissue away from a distal end of the needle and/or from a distal end of a tubular member that is in fluid communication with a substance source. A substance is configured to be expelled into the anatomy through the expandable member. The blocking member is configured to restrict or prevent the substance from being expelled through the portion of the expandable member that includes the blocking member.

The invention relates to an injection device. Exemplary embodiments of the invention comprise an application element, an injection needle, an injection needle housing, a drive system for the injection movement, and a retraction system. In exemplary embodiments, a substance is injected during the retraction movement of the injection needle.

A self-retracting syringe has an injection assembly and a retraction assembly. The injection assembly has a housing, a spring rest, and a spring that is restrained initially in compression between the housing and the spring rest. A plunger rod is disposed inside the coil of the spring. A coupler in contact with the spring rest and the plunger rod releasably couples the plunger rod to the spring rest. When a latch is released, the plunger rod moves distally to urge a seal forward, which seal movement causes a hypodermic needle to extend and a medicament to be expelled through the hypodermic needle. A retraction assembly returns the hypodermic needle into the syringe body after the medicament is expelled. Embodiments of retraction assembly provide a port through which fluid may be introduced into the syringe through said hypodermic needle. Methods for filling the syringe are also described.

The present disclosure relates to a syringe including a container, for containing a primary fluid, and at least one secondary fluid chamber configured to contain a secondary fluid. The container comprises a proximal end and a distal end and having a distal end opening at the distal end. The syringe further comprises a stopper, movably arranged within the container; and a plunger engageable with the stopper and configured to apply a force to the stopper to move the stopper within the container towards the distal end of the container, to expel primary fluid from the container through the distal end opening. The plunger is further configured to expel secondary fluid from the at least one secondary fluid chamber towards the distal end opening, to expel at least a portion of a residual volume of primary fluid through the distal end opening. A plunger system and assembly for a syringe and methods of expelling fluid from a syringe are also disclosed.

In some embodiments a system and method are described for safeguarding a hazard. The hazard, for example a needle point, may be moved between a protected retracted position, an active extended position and/or an intermediate position. Optionally in the retracted position, the hazard may be protected inside a housing. Optionally in the extended position, the hazard may be exposed. Optionally, in the intermediate position the hazard may be partially protected and/or concealed, for example by a shield and/or in an indentation. In some embodiments, compromising a shield causes the hazard to be retracted to the retracted position.

In some examples, a device, which may be used to access vasculature or another hollow anatomical structure of a patient, includes a housing, a cannula mechanically coupled to a housing distal end, and a needle configured to be locked in a deployed configuration in which the needle extends within a cannula lumen and protrudes from the cannula distal end. The needle is configured to slide proximally through the cannula lumen from the deployed configuration into a retracted configuration in which at least a portion of the needle is within a housing lumen. The device further includes at least one needle guide configured to maintain the needle along a path in the housing lumen substantially parallel to the needle guide when the needle moves between the deployed configuration and the retracted configuration.