Injector devices and methods for using them to deliver medicament into a patient's body, e.g., sub-retinally within an eye, are provided. The injector includes an injector cannula having a soft injector tip. A retractable tip protector tube is slidably disposed on the flow cannula between an extended position in which the tip protector tube covers the entire injector tip, and a retracted position in which the tip protector tube is retracted proximally thereby exposing at least part of the injector tip. Accordingly, the tip protector tube protects the injector tip from being damaged while advancing the injector tip to a target injection site.

An autoinjector having a housing for receiving a product container, a propelling member, a drive for automatically discharging a liquid product, a needle-guard spring for pretensioning a needle-guard sleeve, a grid with a multiplicity of latch elements arranged along the longitudinal direction, and an engagement element which, by engagement in the grid, blocks a discharging movement of the propelling member. A control element of the autoinjector interacts with the engagement element via a control cam such that, when the control element moves in the distal direction by the needle-guard spring, the engagement element is brought into engagement with the grid. Since the force of the needle-guard spring is used for the engagement, the engagement element can be mounted without specific elastic force acting in an engagement direction, and can also be mounted in an articulated manner and/or in a manner limited to pure guidance in the engagement direction.

Disclosed is a device for the parenteral delivery of a medication, such as a drug. The device includes upper and lower housings in which the upper housing is configured to move relative to the lower housing as a result of application of an external force to permit the user of the device to control the rate at which the drug is administered.

A device configured to administer a medication can comprise a lower housing that includes a housing latch. The device can further comprise a needle guard that is movable relative to the lower housing along a first direction from a first position to a second position so as to expose a needle, and an upper housing supported relative to the lower housing. The upper housing can be configured to move with respect to the lower housing along a second direction from a pre-use position to a dispensed position. The housing latch can releasably interfere with the upper housing when the upper housing is in the pre-use position so as to prevent the upper housing from moving toward the dispensed position, and the movement of the needle guard toward the second position, causes the interference to be removed, thereby allowing the upper housing to move toward the second position.

A medicament delivery device system for delivery of a medicament from a cartridge (10). The system comprises a first container (11) for storage of a first substance, a second container (12) received in the first container (11) for storage of a second substance, and valve means (68) for closing a distal end of the second container (12). The system further comprises a disposable cassette (102) and a reusable firing unit (200). The cassette (102) has a body (104) for receiving the cartridge (10), and a mixing element (148) for displacing the second substance into the first chamber (16) in a mixing stroke, to mix with the first substance to form the medicament. The firing unit (200) comprises a drive element (208) for expelling the medicament from the first chamber (16) in a delivery stroke and a trigger arrangement (240) for initiating the delivery stroke.

A needle protection assembly, adapted to protect a tip of a hypodermic needle, comprising a shield adapted, in a protected operative orientation of the needle protection assembly, to shield the tip of the hypodermic needle, a locking element including at least one slot, the slot including at least three surfaces corresponding to three operative orientations of the shield, at least one slot engaging element, functionally associated with the shield, the slot engaging element being disposed within the slot of the locking element and movable relative thereto, between the surfaces, so as to transition the shield between the three operative orientations, and at least one biasing element, adapted for axial biasing of the shield, wherein the three operative orientations include a storage operative orientation, an injection operative orientation, and a needle protection operative orientation.

A housing for a medicament delivery device is presented having a shell extending along an axis in an axial direction from a proximal end to a distal end, and a medicament delivery member guard moveably attached to the shell. The medicament delivery member guard extends in the axial direction from a proximal end to a distal end. The shell has a slit extending in the axial direction and the medicament delivery member guard has a protrusion extending in the axial direction, and/or the medicament delivery member guard has a slit extending in the axial direction and the shell has a protrusion extending in the axial direction. The medicament delivery member guard is configured to move in the axial direction from a first axial position relative to the shell (12) to a second axial position relative to the shell.

A medicament delivery device is presented having a housing with an inner surface structure, a delivery member cover slidably arranged in the housing, a medicament container housing arranged in the housing, a rotator configured to cooperate with the inner surface structure, the rotator being in axial engagement with the medicament container housing, wherein the delivery member cover is configured to be moved axially from an extended position relative to the housing to a retracted position, thereby causing the rotator to rotate from a first rotator position to a second rotator position, a forward-biased plunger rod extending through the rotator and having a first axial engagement position with the rotator when the rotator is in the first rotator position and in the second rotator position, wherein the rotator has an engagement structure configured to engage with the inner surface structure when the rotator is in the first rotator position to prevent forward movement of the rotator, and wherein the rotator is configured to disengage from the inner surface structure when the rotator is rotated from the first rotator position towards the second rotator position, causing the rotator, the plunger rod and the medicament container housing to move forward an auto-penetration distance in the housing.

A catheter assembly (10) comprises a catheter (22), a needle (12) having a sharp distal tip, a catheter hub (14) housing the catheter (22), the catheter hub (14) having a collar (34) including a notch (36), a needle shield (20) connected to the catheter hub (14) when the needle (12) is in a first position, and a clip (40) disposed in the needle shield (20) that cooperates with the needle (12), wherein the clip (40) engages the catheter hub (14) in the first position of the needle (12), and the clip (40) disengages the catheter hub (14) via the notch (36) when the needle (12) is retracted to a second position to cover at least a portion of the needle (12). The clip (40) is mounted in the outer housing (38) of the needle shield (20) via a spade (66) having an outer wall (70) exposed to the outside of the needle shield (20), in order to reduce the overall width of the needle shield (20).

A needle assembly is disclosed, for use with an injection device. The needle assembly comprises a needle hub (20) having a needle (22) and a needle shield (40) arranged for relative axial movement with respect to the needle hub, between a retracted position in which the tip of the needle projects beyond a forward end of the shield and an extended position in which the tip of the needle does not project beyond the forward end of the shield. The needle shield (40) is axially biased towards the extended position. The needle shield (40) is further arranged to be torsionally biased for relative rotational movement with respect to the needle hub (20).