A device for spinal correction includes a stabilizer assembly including a hinge including a first rod-bearing leaf; a second rod-bearing leaf rotatably coupled to the first rod-bearing leaf to provide coronal or sagittal freedom of movement, or both, of the stabilizer assembly; a locking mechanism to lock the first and second rod-bearing leaves at a desired angle; a first stabilizing rod coupled to the first rod-bearing leaf; a second stabilizing rod coupled to the second rod-bearing leaf; and a plurality of monoaxial or polyaxial links, wherein each monoaxial or polyaxial link is movably coupled to the first or second stabilizing rod and is movably couplable to a first spinal rod or a second spinal rod fixed to the spine; wherein the stabilizer assembly is couplable to the first or second spinal rod to stabilize the spine to prevent compression, distraction, or translation of the spinal cord during a spinal correction.

A surgical connector is provided. The connector includes a first member including a mating surface engageable with an implant and a locking element and a second member translatable relative to the first member to urge the locking element into engagement with the implant. At least one of the members is connectable with a surgical instrument. Systems and methods of use are disclosed.

A system for applying a manipulative force to a target region of a spinal column during a surgical procedure is provided with at least four pedicle screws, at least four elongated levers configured to temporarily engage with the pedicle screws, a linking member configured to link at least two of the elongated levers in a axial direction such that they move in unison, and a cross-linking member configured to link at least two of the elongated levers in a transverse direction such that they move in unison. When the system is assembled, it permits an operator to move the at least four elongated levers in unison to simultaneously rotate the at least four pedicle screws about a spinal column roll axis. Related methods are also provided.

A surgical instrument comprises a first arm including a first closed loop engageable with a first spinal implant disposed with a first vertebral surface. A second arm is movable relative to the first arm and includes a second closed loop engageable with a second spinal implant disposed with a second vertebral surface. Surgical systems, constructs, implants and methods are disclosed.

Enzymatic and non-enzymatic detectors and associated membrane apparatus, and methods of use, such as within a fully implantable sensor apparatus. In one embodiment, detector performance is controlled through selective use of membrane configurations and enzyme region shapes, which enable accurate detection of blood glucose level within the solid tissue of the living host for extended periods of time. Isolation between the host's tissue and the underlying enzymes and reaction byproducts used in the detectors is also advantageously maintained in one embodiment via use of a non-enzyme containing permeable membrane formed of e.g., a biocompatible crosslinked protein-based material. Control of response range and/or rate in some embodiments also permits customization of sensor elements. In one variant, heterogeneous detector elements are used to, e.g., accommodate a wider range of blood glucose concentration within the host. Methods of manufacturing the membranes and detectors, including methods to increase reliability, are also disclosed.

An instrument includes a shaft and a mating element that extends from the shaft. The mating element is configured to engage a mating element of a bone fastener to move a receiver of the bone fastener relative to a bone anchor of the bone fastener. Implants, systems, constructs, instruments and methods are disclosed.

A bone fastener includes a first member having an inner surface defining an implant cavity. A second member is disposed with the first member. The second member is configured to penetrate tissue. The second member includes a head defining a socket. A part is disposed at an angle relative to the head. The part includes a top surface configured for disposal of an implant and an opposite bottom surface configured to rotatably engage the head to selectively adjust the angle. The part includes an opening that is in communication with the socket. The opening has a diameter that is less than that of the socket. Implants, systems, constructs, instruments and methods are disclosed.

An assembly for remotely manipulating a patient's spine. A compressor/distractor mechanism attaches to spinal anatomy or vertebral screws on adjacent vertebrae at a spinal surgical site on a patient's spine. A flexible cable is operatively connected to the compressor/distractor mechanism and to a control mechanism. The control mechanism manipulates the flexible cable, controlling the compressor/distractor mechanism to compress or distract the vertebrae. A rotatable surgical table with a remote control can be used in place of the compressor/distractor mechanism and the control mechanism. The rotatable surgical table can rotate the patient to place the spinal surgical site in a desired compressed or distracted position, and to place the patient in a desired orientation with respect to a horizontal reference plane. The assembly permits manipulation of the spine at the surgical site via a posterior approach, while the surgeon can also manipulate the spine at the surgical site via an anterior, lateral or oblique approach.

Implementations described herein include a system that may include a deliver device, an annular anchor and an implant. The delivery device may include a distal end, a proximal and a lumen extending from the distal end to the proximal end. The annular anchor may be removably coupleable to the distal end of the delivery device. The annular anchor may be implantable at a target site in a patient via manipulation of the delivery device. The delivery device may be extendable outside the patient when the anchor is implanted at the target site. The implant may be deliverable through the delivery device to the target delivery site and implantable through the annular anchor. The delivery device may be coupled to the annular anchor to control a trajectory of the implant to the target site.

An access system for spinal surgery through a lateral approach comprises a tissue retractor including a center body supporting a centering guide having an elongate opening defining an alignment axis. A pair of retractor blades are movably supported by the center body one blade each on either side of said the centering guide, each retractor blade having a proximal end and a distal end, the distal ends of each retractor blade being configured for placement adjacent a spinal column of a patient. A plurality of elongate disc anchors is provided, each disc anchor being sized for individual removable receipt through the centering guide opening. Each disc anchor has a length such that the distal end of each disc anchor extends distally beyond the distal ends of the retractor blades when each disc anchor is respectively disposed in the centering guide opening.