A dynamic disc assembly has a superior end plate, an inferior end plate, and a core. The core has surfaces of an annular Fresnel shape and a linear Fresnel-like shape combined to control the dynamic range of motion (ROM) movement arranged to match anatomical ROM. The core is interposed between and held against interior surfaces of the superior end plate and the inferior end plate. The assembly further has a pair of coupling cords, one coupling cord at each lateral end of the superior and inferior end plates wherein each lateral end of each end plate has one or more cord connections attached and affixed to the coupling cord to form and retain the dynamic disc assembly.

A tibial component of a total knee prosthesis which includes a base element provided with a medial portion and a lateral portion, which can be fixed on the proximal surface of the tibia-; The base element has shape and dimensions that are complementary to those of at least one protective insert (one single insert or two separate inserts: one medial and one lateral). —— In particular, the medial portion is provided with coupling elements for coupling by pressure to the insert (a configuration generally termed “fixed insert”). ——— By contrast, the at least one insert is resting on the lateral portion.

In some embodiments, a revision implant includes a body extending between a first planar surface and a second planar surface and a head extending from the first planar surface of the body. The head is configured to couple the revision implant to at least one additional component of a multi-component prosthesis. At least one coupling mechanism is configured to couple the body to a first bone.

Proposed is an augment implant and, more specifically, is an augment implant, in which a body part of the porous structure is combined with a frame part of a non-porous structure to increase the mechanical strength of the body part and to prevent damage to the body part due to external forces, bone ingrowth is maximized by minimizing the area of the frame part, the augment implant can be inserted in various directions, not just in a specific direction, and when the augment implant is manufactured by 3D printing, a support is connected to the frame part so that in a process of removing the support, the support can be easily removed without damage to the porous structure.

A prosthetic disc for insertion between adjacent vertebrae includes a core having upper and lower curved surfaces, upper and lower plates, and peripheral restraining structure on at least one of the upper plate, the lower plate and the core. Each plate has an outer surface which engages a vertebra and an inner curved surface which slides over the curved surface of the core. The peripheral restraining structure serves to hold the core against a curved surface of at least one of the plates during sliding movement of the plates over the core.

This disclosure includes apparatus and methods to attach an orthopedic device to a bone. The method can comprise locating a baseplate on a glenoid of a patient, the base plate including at least a first fastener bore, creating a first post hole in the glenoid for locating a first fixation post, the first fixation post including a quasi-spherical head and a porous metal sleeve, and driving the first fixation post through the first fastener bore and into the first post hole. The porous metal sleeve can engage the first post hole and the quasi-spherical head can contact at least the first wall of the first fastener bore to removeably lock the quasi-spherical head to the baseplate. Driving the first fixation post can create an initial compression between the baseplate and the glenoid. The porous metal sleeve can receive bone ingrowth to maintain the initial compression.

A shoulder implant system comprising a glenoid implant; a baseplate comprising an implant facing surface to face the glenoid implant; wherein the glenoid implant comprises at least one fixation element configured to engage with at least one fixation element of the baseplate; wherein the at least one fixation element of the glenoid implant comprises a center post having a distal end; wherein the at least one fixation element of the baseplate comprises a center post receptacle; wherein the baseplate comprises an outer periphery; wherein the implant facing surface of the baseplate comprises a channel which extends from the outer periphery of the baseplate to the center post receptacle of the baseplate; and wherein the channel is configured such that, during an assembly of the glenoid implant and the baseplate, the distal end of the post is movable in the channel from the outer periphery of the baseplate to the center post receptacle of the baseplate.

An artificial replacement disc includes a pair of substantially parallel plates formed to occupy a space defined by vertebral endplates, each of the plates including a plurality of spikes on a first surface and a concave trough formed on a second surface opposite of the first surface. A mobile core includes a core rim with opposing convex surfaces extending from opposite sides of the core rim, the mobile core being capable of being disposed between the pair of plates to permit the vertebral endplates to move relative to one another. The spikes on each of the plates extend substantially away from the mobile core and the convex surfaces are formed to integrally fit within the concave trough of at least one of the plates. The core rim limits lateral movement of the mobile core relative to the parallel plates. One or more insertion tools for inserting and implanting the replacement disc are also described.

A device for bone regeneration intended to form a barrier for protecting a space above a surface of a bone, for example a tooth, to allow, after insertion of a biomaterial, which, while mineralising, will form new bone above existing bone, includes a self-supporting barrier-forming element in the shape of a dome (1) or a shell, and means for attaching the barrier-forming element above the bone surface in order thus to form a volume where the biomaterial can be arranged to mineralise and form new bone grafting itself onto the previously present bone, is characterised in that the barrier-forming element in the shape of a dome (1) or shell is made of a material, specifically a non-resorbing material, such that the barrier-forming element is radiotransparent

Methods, compositions, and systems are provided for characterization of modified nucleic acids. In certain preferred embodiments, single molecule sequencing methods are provided for identification of modified nucleotides within nucleic acid sequences. Modifications detectable by the methods provided herein include chemically modified bases, enzymatically modified bases, abasic sites, non-natural bases, secondary structures, and agents bound to a template nucleic acid.