Anchoring devices, anchoring systems for intervertebral implants, intervertebral implants, and instruments and methods for implanting implants are disclosed. In preferred configurations, these various objects share the feature of comprising or cooperating with an anchoring device (1) having a body comprising at least one curved plate (10) elongated along a longitudinal axis (L), designed to be inserted through a passage (21) crossing at least a part of implant (2), in order to penetrate into at least one vertebral endplate and attach implant (2) onto this vertebral endplate by means of at least one stop retaining the implant, characterized in that the body comprises at least one longitudinal rib (11) on at least a part of at least one of its faces, said rib (11) being designed to cooperate with a groove (211) made in passage (21) of implant (2). In some preferred configurations, anchoring device (1) comprises withdrawal stops or latches (12), and/or means (40) for withdrawing the anchor from an inserted position.

An expandable interbody device for implantation within an intervertebral space is provided, together with methods and tools for use therewith. The interbody devices include a leading first and trailing second bearing member configured to expand laterally via connecting portions disposed at the trailing end of the first being member and at least the leading end of the second bearing member. In some forms, the connecting portions have an arcuate configuration. The insertion tool is configured expand the interbody device by holding the first bearing member while shifting the second bearing member.

A system comprising a fusion cage and at least one engagement member is provided. The fusion cage includes a first member and a second member. The engagement member is configured to retain the first and second members in an expanded state while simultaneously fixing the fusion case to adjacent vertebrae.

A system of prosthetic implants for a total knee replacement procedure is provided. The system includes a tibial component of a knee joint implant, a tibial insert configured to be positioned against the superior side of the platform of the tibial component, a first femoral component of a knee joint implant, and a second femoral component of a knee joint implant.

The present disclosure provides a system of gender specific pharmaceuticals. The system includes a first package of a pharmaceutical for use by a male and a second package of a pharmaceutical for use by a female. The first package includes at least one male dosage having a first dosage amount, an insert positioned in the first package, the insert including a recommended male dosage and a recommended female dosage that is different than the male dosage, and a male label coupled to the first package, the label including a male gender specifier. The female package includes at least one female dosage having a second dosage amount that is smaller than the first dosage amount, an insert positioned in the first package, the insert including a recommended male dosage and a recommended female dosage that is different than the male dosage, and a female label coupled to the second package, the female label including a female gender specifier, wherein the female gender specifier is different than the male gender specifier.

In one embodiment a method of implanting a prosthetic includes implanting a first member including a concave articulation surface portion defined by a first radius of curvature in a first bone, implanting in a second bone a second member including a first convex articulation surface portion defined by a second radius of curvature and a second convex articulation surface defined by a third radius of curvature, wherein the second convex articulation surface is defined by the lemon portion of a spindle torus and each of the second radius of curvature and the third radius of curvature has a length that is different from the length of the first radius of curvature by less than 0.05 millimeters and wherein the origin of the second radius of curvature is not coincident with the origin of the third radius of curvature, and bringing the first member into slidable contact with the second member

An expandable interbody fusion device includes superior and inferior endplates that are configured to receive a sequentially inserted stack of interlocking expansion members or wafers. The like-configured wafers include features on their top and bottom surfaces that interlock the wafers in multiple degrees of freedom so that the wafer stack is not disrupted when the fusion device is fully expanded. One of the interlocking features includes a plurality of prongs projecting from an upper surface of the wafers and into a recess defined in the lower surface of an adjacent previously inserted like-configured wafer. The prongs and recesses are configured to prevent retrograde movement of each new wafer in a direction opposite the direction of insertion. Other interlocking features prevent movement in the direction of insertion, transverse to the insertion direction and vertically within the stack.

The disclosure includes a method for providing prosthetic implants for a total knee replacement procedure. This method includes receiving data representative of a knee joint of a patient and determining anatomical parameters from the received data. The method also includes creating a graphical model of the knee joint based on the determined anatomical parameters, and providing a femoral component of a knee joint implant based on at least one of the determined anatomical parameters and the graphical femoral portion. This method also includes providing at least one cutting instrument configured to facilitate removing a portion of the femur of the patient based on at least one of determined anatomical parameters and the graphical model.

An expandable interbody device for implantation within an intervertebral space is provided, together with methods and tools for use therewith. The interbody devices include a leading first and trailing second bearing member configured to expand laterally via connecting portions disposed at the trailing end of the first being member and at least the leading end of the second bearing member. In some forms, the connecting portions have an arcuate configuration. The insertion tool is configured expand the interbody device by holding the first bearing member while shifting the second bearing member.

The present invention provides an intervertebral implant for implantation in a treated area of an intervertebral space between vertebral bodies of a spine. The implant includes a spacer portion having an inferior and superior surface, wherein the inferior and superior surfaces each have a contact area capable of engaging with anatomy in the treated area, and the inferior and superior surfaces define a through-hole extending through the spacer body. The present invention further provides screw holes extending from a side portion to the inferior and superior surfaces of the spacer portion and a plate portion coupled to the spacer portion through a coupling means, wherein the plate portion contains screws holes for receiving screws. A screw back out prevention mechanism adapted on the plate portion and prevents the back out of screws from the screw holes.