A modular implant for performing an intervertebral fusion on adjacent vertebral bodies in a patient including a first spacer portion, a second spacer and a container having a first end and a second end, the first end of the container constructed to operably engage a first spacer and the second end of the container constructed to operably engage the second spacer.

Computer implemented methods of producing a porous implant are provided including obtaining a 3-D image of an intended tissue repair site; generating a 3-D digital model of the porous implant based on the 3-D image of the intended tissue repair site. The method also includes determining an implant material and an amount of a porogen to add to an implant material to obtain a desired porosity of the porous implant. The desired porosity is based on a combination of macropores, micropores and/or nanopores structures. The 3-D digital model developed is stored on a database coupled to a processor, wherein the processor has instructions for combining the implant material with the porogen based on the stored 3-D digital model and for instructing a 3-D printer to produce the porous implant. A layered 3-D printed porous implant prepared by the computer implemented method is also provided.

A covering for delivering a substance or material to a surgical site is provided. The covering, with substance provided therein, may be referred to as a delivery system. Generally, the covering may be a single or multi-compartment structure capable of at least partially retaining a substance provided therein until the covering is placed at a surgical site. Upon placement, the covering may facilitate transfer of the substance or surrounding materials. For example, the substance may be released (actively or passively) to the surgical site. The covering may participate in, control, or otherwise adjust the release of the substance. In various embodiments, the covering may be formed of a collagen material and is suitable for a variety of procedure specific uses.

A central inflatable distractor and a perimeter balloon are inserted into the disc space in uninflated configurations. The central inflatable distractor is then expanded, thereby distracting the vertebral endplates to the controlled height of the central inflatable distractor. The perimeter balloon is then inflated with a curable substance. The perimeter balloon expands as it is filled with the curable substance and conforms to the void remaining in the disc space around the central inflatable distractor, thereby creating a horseshoe shape. Once the flowable material in the perimeter balloon has cured, the central inflated distractor can be deflated and removed. The remaining void (or inner space) is then packed with graft for fusion.

A bone implant composition and methods thereof include bone material made into various implant shapes including a cylinder having an outermost layer and an inner layer completely surrounded by the outermost layer. The bone implant compositions and methods include a bag or cylindrical tube made from a bone material which may be filled with additional bone material.

Computer implemented methods of producing a mesh implant having a compartment to enclose a bone material therein are provided. These methods include generating a 3D digital model of the mesh implant having the compartment, the 3D digital model including a virtual volume of the compartment and a virtual depth, thickness and volume of the mesh implant; generating a 3D digital model of a covering configured for closing the compartment of the mesh implant, the 3D digital model including a virtual volume of the covering for closing the compartment of the mesh implant; and instructing a 3D printer coupled to a computer to generate the mesh implant based on the 3D digital models. A computer system for making a mesh implant and a delivery system including the mesh implant are also provided.

An expandable implant is disclosed having an adjustable height for insertion between two adjacent bony structures or joint surfaces, for example between two adjacent spinal vertebrae. The implant includes at least one gear associated with at least one threaded shaft. Rotation of the gear engages the threaded shaft to expand the implant. The implant can be inserted in a collapsed configuration and expanded in situ. The invention also provides methods for using the implant to facilitate arthrodesis or fusion of adjacent joint surfaces or spinal vertebrae.

A polyaxial cannulated screw having a resilient expandable body capable of supporting compressive and cyclic loads. The expandable body provides an artificial disc prosthesis by use of the expandable body that mimics the properties of the natural disc by maintaining the intervertebral disc space through a full range of natural motion, absorbing shocks and permitting a natural range of motion. A U-shaped saddle attached to a spherical ball permits optimum positioning of a rod member by polyaxial placement.

A covering for delivering a substance or material to a surgical site is provided. The covering, with substance provided therein, may be referred to as a delivery system. Generally, the covering may be a single or multi-compartment structure capable of at least partially retaining a substance provided therein until the covering is placed at a surgical site. Upon placement, the covering may facilitate transfer of the substance or surrounding materials. For example, the substance may be released (actively or passively) to the surgical site. The covering may participate in, control, or otherwise adjust, the release of the substance.

A hybrid spinal implant for performing an intervertebral fusion procedure can include a pair of spacers separated by an expandable container that are formed of a porous titanium scaffold material. A connecting rod can span longitudinally between the pair of spacers. The spacers can be formed of titanium or PEEK, with endplates that are formed of the porous titanium scaffold material. The endplates can be bioactive. Exposed surfaces of the porous titanium scaffold material can be coated in a snag-preventing substance. The expandable container can be formed of a mesh material.