The present disclosure provides for an assembly and methods of use to deploy a segmented medical device to a body vessel. The assembly includes a multiportion medical device which has a plurality of detachable components, a balloon catheter, and a retention member at the distal end of the balloon of the balloon catheter so as to alter the inflation profile of said balloon, such that microsliding of the device over the exterior of the balloon is prevented or minimized.

A prosthetic heart valve comprises a collapsible and expandable support frame comprising a longitudinal axis. The frame comprises a first circumferential undulating structure defining an outflow end of the frame, and a second circumferential undulating structure spaced apart from the first circumferential undulating structure. The frame also comprises a plurality of struts longitudinally aligned with the longitudinal axis of the frame, and connecting the first circumferential undulating structure to the second circumferential undulating structure. Each strut of the plurality of struts comprises a first end terminating at a trough of the first circumferential undulating structure, and a second end terminating at a peak of the second circumferential undulating structure. The prosthetic heat valve also comprises a biological tissue valve coupled to the frame. The prosthetic heart valve is configured to be collapsed for introduction into a patient using a catheter and to be expanded for deployment at an implantation site.

Examples of a stent is provided with interlocking joints removably coupling adjacent axial stent segments. Mating elements forming the interlocking joints maintain circumferential and axial engagement when the stent is in the radially compressed configuration, for example, during tracking of the stent to a treatment site of a body vessel, and become disengaged during radial expansion of the stent. The length of mating elements may be sized as large as the strut width. When disengaged, the disconnected the axial stent segments remain discrete stent structures separated from one another along the point of treatment.

A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provides high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold may be formed from degradable material, or may be formed from non-degradable material and will be modified to expand and/or uncage after deployment.

A stent with enhanced deployment characteristics to prevent twisting of the stent during delivery or deployment. The stent may include a first wire segment and a second wire segment that are linked together by at least one connector. The first wire segment may be rotatably connected to a first side of the at least one connector and the second wire segment may be rotatably connected to a second side of the at least one connector. The at least one connector may include an elongated body having at least two passages including a first passage for receiving the first wire segment and a second passage for receiving the second wire segment. The first and/or second wire segments may include enlargements to prevent the wire segments from being pulled out of the passages.

A stent is disclosed, which is capable of preventing connection sections from overlapping with each other in a radial direction when a force is applied inadvertently thereto by adjusting distribution of the connection sections with respect to a direction of helix of the strut. A link portion of the stent includes connection sections provided integrally with one helical portion and other helical portions adjacent to each other, and disposed in positions overlapped with each other at least partly along an axial direction of a cylindrical shape in a state of opposing to each other, and a biodegradable material connecting connection sections by being interposed between the connection sections.

Excessive dilation of the annulus of a mitral valve may lead to regurgitation of blood during ventricular contraction. This regurgitation may lead to a reduction in cardiac output. Disclosed are systems and methods relating to an implant configured for reshaping a mitral valve. The implant comprises a plurality of struts with anchors for tissue engagement. The implant is compressible to a first, reduced diameter for transluminal navigation and delivery to the left atrium of a heart. The implant may then expand to a second, enlarged diameter to embed its anchors to the tissue surrounding and/or including the mitral valve. The implant may then contract to a third, intermediate diameter, pulling the tissue radially inwardly, thereby reducing the mitral valve and lessening any of the associated symptoms including mitral regurgitation.

To provide a stent delivery system configured to prevent twisting of a strut during expansion of a stent. A balloon has a plurality of limb portions folded at a plurality of folding pleats in a deflated state. The limb portions are folded in a first circumferential direction to surround the shaft as seen from a proximal end side of an axial direction of the shaft. The strut of the stent has helical portions formed in a helical shape extending along a second circumferential direction opposite to the first circumferential direction as seen from the proximal end side of the axial direction with being centered on an axis extending along the axial direction of the shaft.

A method for fabricating an embodiment of a medical device comprising the steps of: preparing a biodegradable polymeric structure; coating the biodegradable polymeric structure with a polymeric coat including a pharmacological or biological agent; cutting the structure into patterns configured to allow for crimping of the cut structure and expansion of the cut structure after crimping into a deployed configuration.

A woven, self-expanding stent device has one or more strands and is configured for insertion into an anatomical structure. The device includes a coupling structure secured to two different strand end portions that are substantially aligned with each other. The two different strand end portions include nickel and titanium. The coupling structure is not a strand of the device.