A drug injection device (1) comprising a dose expelling mechanism for expelling drug from a reservoir through a reservoir outlet, the dose expelling mechanism comprising: a first component (40), a second component (10, 10, 15, 10, 15), and a torsion spring element (20) for inducing relative rotation between the first component (40) and the second component (10, 10, 15, 10, 15) to execute a dose expelling operation, the torsion spring element (20) extending along a longitudinal axis and comprising: a first spring end portion (22) being rotationally restrained with respect to the first component (40), and a second spring end portion (23) exhibiting an end portion inner diameter in a relaxed state of the torsion spring element (20), wherein the second spring end portion (23) is fitted over a spring receiving portion (11) of the second component (10, 10, 15, 10, 15), the spring receiving portion (11) having a transversal dimension which is larger than the end portion inner diameter, and the fitting of the second spring end portion (23) over the spring receiving portion (11) being configured to provide a sticking friction engagement between the two when the torsion spring element (20) is strained to exert a maximum in-use torque.

A system comprising a state changing appliance and a drug delivery device, the state changing appliance comprising first interface means for rotationally locking to a first exterior portion of the drug delivery device, second interface means for rotationally locking to a second exterior portion of the drug delivery device, the first exterior portion and the second exterior portion being angularly displaceable relative to one another from a first relative position to a second relative position, which second relative position defines a set dose to be expelled by the drug delivery device, and limiter means for limiting a relative angular displacement between the first interface means and the second interface means.

An injection device having a delivery element with an inner thread may be driven by rotation and includes a cylindrical outer wall region, which is substantially smooth. Such features provide a delivery element configured such that it is less intimidating to patients than known threaded rods, and may facilitate easy cleaning. The delivery element may be non-rotatably guided and axially spring-loaded, and may be inserted axially into the housing when the reservoir is replaced. The driving thread element for the delivery element may be mounted in the vicinity of the distal end of the housing.

The present invention relates to a medicament delivery device (10) comprising a housing (12, 14); a medicament container holder (90), arranged movable in relation to said housing (12, 14) and capable of accommodating a medicament container (92); an biased activator (160) comprising a plunger rod (164), which plunger rod (164) is arranged to act on the medicament container (92) for delivering a dose of medicament through a medicament delivery member (102 when said biased activator (160) is operated; a manually operable dose setting member (72) operably connected to both said housing and said medicament container holder such that manual operation of said dose setting member (72) will cause the medicament container holder (90) with the medicament container (92) to move towards said plunger rod (164) for setting a dose of medicament to be delivered; a dose drum (56) releasably connected to the dose setting member (72) through a releasable connection mechanism (68, 84I) such that when the dose setting member is operated, said dose drum (56) is displaced from an initial position to a set dose position; a release mechanism (116) operably connected to said biased activator (160), wherein, when said plunger rod (164) is moved to an end position of the dose delivery operation, said release mechanism (116) is arranged to act on said connection mechanism (68, 84I) for releasing said dose drum (56) from said dose setting member (72). The invention is characterised in that said release mechanism is arranged with a locking mechanism (130, 84II) arranged to lock said dose setting member (72) from displacement as the connection mechanism (68, 84I) is operated for releasing said dose drum (56) from said dose setting member (72).

An injection device incorporating a dose setting mechanism is presented where the dose setting mechanism contains a dose selector having one or more dose stops corresponding to a finite set of predetermined fixed doses, where the set of finite predetermined fixed doses includes a lowest fixed dose and one or more higher fixed doses, and where at least one of the one or more higher fixed doses is equal to the lowest fixed dose plus a fractional amount of the lowest fixed dose. The dose setting mechanism can further include a floating spline that is rotationally engaged with a snap element such that the snap element can rotate relative to the floating spline during both dose setting and dose delivery.

A portable device that accurately determines the liquid dosage that a patient is consuming while also regulating their use of the device is provided and is suitable for use with substances like medical cannabis and opioids. A liquid dispenser device is reusable with replaceable liquid cartridges. These cartridges can contain multiple dosages of a specific liquid, which is more convenient for the patient and reduces cost. The device uses a micro-motor, translational screw, and encoder to determine the exact amount of liquid displaced from the cartridge. That exact amount of liquid is dispensed from a small nozzle into a mouthpiece. The mouthpiece is replaceable and can be tailored to meet the patient's specific needs. For example, the mouthpiece can be adapted for dispensing under the tongue of the user or directly into a drink. The device can also have locking mechanisms and wireless communication capabilities. The device will not allow patients take over the maximum doctor recommended dosage, and regulates the time interval of those dosages based on doctor recommendation. Wireless communication can be used to communicate with other devices to ensure that the patient is not overlapping their dosages. Wireless communication can also be used to sync the device to a smartphone, tablet, or computer app to track patient data, usage, and the patient can also set a timer/alarm.

A drug delivery device for selecting and dispensing a number of user variable doses of a medicament includes a housing, a cartridge holder for receiving a cartridge, a lead screw and means for driving the lead screw during dose dispensing. The lead screw is coupled to the cartridge holder such that the cartridge holder is axially displaced with respect to the housing and the lead screw during dose dispensing.

A drug delivery device for setting and dispensing of a dose of a medicament includes a housing extending in an axial direction and a piston rod to operably engage with a piston of a cartridge to displace the piston in a distal axial direction. The drug delivery device further includes a drive spindle operably engageable with the piston rod during dose dispensing and a drive member axially displaceable relative to the drive spindle against the action of a spring element during dose setting and being threadedly engaged with the drive spindle to form a spindle gear.

A drive mechanism of a drug delivery device for dispensing of a dose of a medicament includes a housing extending in an axial direction, a piston rod to operably engage with a piston of a cartridge to displace the piston in an axial distal direction, and a drive sleeve extending in the axial direction and being rotatable in a dose incrementing direction against the action of a spring enclosing at least an axial portion of the drive sleeve. The drive mechanism further includes a dose limiting member threadedly engaged with the drive sleeve, rotatably locked to the housing and at least partially extending radially between the drive sleeve and the spring, and at least one stop located on at least one of dose limiting member and drive sleeve for limiting an axial displacement of the dose limiting member relative to the drive sleeve.

A system comprising a state changing appliance and a drug delivery device, the state changing appliance comprising first interface means for rotationally locking to a first exterior portion of the drug delivery device, second interface means for rotationally locking to a second exterior portion of the drug delivery device, the first exterior portion and the second exterior portion being angularly displaceable relative to one another from a first relative position to a second relative position, which second relative position defines a set dose to be expelled by the drug delivery device, and limiter means for limiting a relative angular displacement between the first interface means and the second interface means.