An apparatus includes a pen body of a drug injection pen including a dosage injection mechanism that produces a rotational motion when the drug injection pen dispenses a fluid. The apparatus also includes a button housing with at least part of a dosage measurement system disposed within the button housing. At least part of the dosage measurement system is coupled to receive the rotational motion from the dosage injection mechanism. The dosage measurement system includes one or more sensors positioned to output a signal in response to the rotational motion when the drug injection pen dispenses a fluid, and a controller coupled to the one or more sensors to receive the signal. A drug delivery control wheel of the drug injection pen is disposed between the body of the drug injection pen and the at least part of the dosage measurement system disposed in the button housing.

A drug injection pen includes a housing shaped to accept a cartridge containing a fluid, and a dosage injection mechanism positioned in the housing to produce a rotational motion and force the fluid out of the cartridge when the drug injection pen dispenses the fluid. A dosage measurement system is disposed in the drug injection pen and is coupled to measure a strain induced in a portion of the dosage measurement system. The dosage measurement system outputs a signal indicative of the strain, and the strain on the portion of the dosage measurement system changes when the dosage injection mechanism dispenses the fluid. The dosage measurement system outputs a signal indicative of the strain when the drug injection pen dispenses the fluid. A controller is coupled to the dosage measurement system, and the controller performs operations including recording the signal output from the dosage measurement system.

A dispensing mechanism for administering a dosage of a medicament includes dosage setting means (7) for setting the dosage of a medicament to be administered; expelling means (15) for expelling a medicament from a medicament container; and coupling means (21) operatively coupled with the dosage setting means (7) and the expelling means (15), wherein the coupling means (21) is arranged to convert displacement of the dosage setting means (7) into a displacement of the expelling means (15) in a first direction, wherein the expelling means (15) includes a ratchet means (18a, 18b), and wherein the mechanism includes a first and a second independently moveable resisting pawl (14a, 14b) means facing a common side of the ratchet means (18), the first and the second resisting pawl means (14a, 14b) being configured to engage with the ratchet means (18a, 18b) and resist displacement of the expelling means (15) in a second direction opposite to said first direction.

A drive and metering apparatus for an injection apparatus for releasing a liquid product, the drive and metering apparatus comprising: a) a housing, b) a dose adjustment member, which is rotatable relative to the housing for adjusting the product dose to be released, c) an actuation member which is displaceable from a non-actuated position, which it assumes while adjusting the product dose to be released, into an actuated position, which it assumes while it releases the product, wherein the displacement of the actuation member into the actuated position triggers a product release and the actuation member comprises an actuation section, which is accessible to a user of the drive and metering apparatus and by means of which the user can displace the actuation member from the non-actuated position into the actuated position, d) wherein the actuation section is arranged distally in relation to the dose adjustment member.

A device for administering needle-free subcutaneous treatment to a patient comprises an actuator configured to deliver a plurality of volumes of a treatment at a plurality of locations on a body of the patient; at least one imaging device configured to detect a movement of the needle-free device from a first location on the body of the patient to a second location on the body of the patient; and a processor configured to determine the second location on the body of the device relative to the first location from the movement of the needle-free device relative to the first location on the body, the processor further configured to determine a volume of the plurality of volumes of the treatment to deliver to the body of the patient at the second location.

A dispensing mechanism for administering a dosage of a medicament includes dosage setting means (7) for setting the dosage of a medicament to be administered; expelling means (15) for expelling a medicament from a medicament container; and coupling means (21) operatively coupled with the dosage setting means (7) and the expelling means (15), wherein the coupling means (21) is arranged to convert displacement of the dosage setting means (7) into a displacement of the expelling means (15) in a first direction, wherein the expelling means (15) includes a ratchet means (18a, 18b), and wherein the mechanism includes a first and a second independently moveable resisting pawl (14a, 14b) means facing a common side of the ratchet means (18), the first and the second resisting pawl means (14a, 14b) being configured to engage with the ratchet means (18a, 18b) and resist displacement of the expelling means (15) in a second direction opposite to said first direction.

A delivery device for delivering a medical fluid to a patient has a housing configured for receiving a container at least partially filled with the medical fluid. The delivery device further has a drive mechanism associated with the housing configured for delivering the medical fluid from the container to the patient in a dosing procedure. The delivery device further has a module configured for detecting at least one of a property of the dosing procedure and a property of the medical fluid. The module has at least one dose detection sensor configured for detecting an initiation, progression, and completion of the dosing procedure based on a position of a stopper within the container. The module further has at least one temperature sensor configured for measuring a temperature of the medical fluid within the container based on a temperature of the container.

The present invention relates to a piston washer assembly (100, 100) for use in a drug delivery device for transferring a distally directed axial force from a piston rod (220) towards a piston (214) of a held cartridge (213). The piston washer assembly (100, 100) comprises a) a proximal part (110, 110) adapted for engagement with the distal portion of a piston rod (220), the proximal part (110, 110) defining a first set of cooperating geometries (115, 115), and b) a distal part (120, 120) configured to engage and abut a piston (214) of a held cartridge (213) and to engage the proximal part (110, 110), wherein the distal part (120, 120) defines a second set of cooperating geometries (125, 125) engaging the first set of cooperating geometries (115, 115). In an initial state of the assembly, the proximal part (110, 110) and the distal part (120, 120) are positioned relatively to each other to define an initial axial dimension (H1) for the assembly. The first set of cooperating geometries (115, 115) and the second set of cooperating geometries (125, 125) are configured to enable relative movement for increasing the axial dimension for obtaining a target axial dimension (H2) but preventing a decrease in axial dimension. The invention further relates to a drug delivery device, a method of assembling a drug delivery device incorporating such piston washer assembly and a method of preparing a piston washer assembly.

An actuation mechanism is presented for a medicament delivery device having a plunger rod arranged to act on a stopper of a medicament container, an actuator arranged slidable and connected to the plunger rod for acting on the stopper when said actuator is operated by displacing it in a longitudinal direction of the actuation mechanism, and an activator for activating the actuation mechanism and for setting a dose. The activator having a generally tubular activator sleeve provided with a spirally extending groove on an outer surface, the groove arranged with a length corresponding to the total amount of medicament to be delivered in a number of doses contained in said medicament container, where the groove is provided with an end wall, a stop ring arranged coaxial with said activator sleeve. The activator sleeve arranged with a follower positioned in the groove and the follower arranged to abut the end wall when the total amount has been delivered.

The present disclosure relates to an injection device for delivery of a liquid medicament including a housing, a cartridge having a tubular shaped barrel filled with a liquid medicament and sealed in a proximal direction by a piston displaceably arranged in the barrel, and a drive mechanism having a piston rod to advance in a distal direction against a proximally facing surface of the piston of the cartridge. The drive mechanism is configured to advance the piston rod in the distal direction by a distance z1 to dispense a reference volume V1 of the medicament when operably engaged with a reference cartridge having a reference diameter D1, and, the cartridge has a diameter D2 smaller than the reference diameter D1 to dispense a volume V2 of the medicament smaller than the reference volume V1 when the piston rod advances in distal direction by the distance z1.