A spring assisted drug delivery device is provided comprising a housing and a lead screw having a longitudinal axis, a distal end and a proximal end that is rotatably fixed during dose setting and dose delivery and axially movable in a distal direction relative to the housing. The device further comprises a drive nut threadedly engaged and screwable along the lead screw threaded shaft and a number sleeve threadedly engaged with the housing to be screwable relative to the housing. A dial link is connected with the drive nut and axially movable and rotatably fixed relative to the drive nut and an inner sleeve is threadedly engaged with the number sleeve, the inner sleeve being axially movable and rotatably fixed relative to the housing. A mid-body is axially fixed inside of the housing. A spring is provided that assists a user of the device during a dose administration step.

A drive mechanism for a medication delivery device is presented having a housing, a rotation member that rotates in a first direction with respect to the housing during setting of a dose of a medication and rotates in a second direction with respect to the housing during delivery of the dose, the second direction being opposite to the first direction. The device also has a piston rod that is displaced in a distal direction with respect to the housing for delivering the dose, a drive member which follows rotational movement of the rotation member in the second direction during delivery of the dose, and a stop member which prevents rotational movement of the drive member with respect to the housing in the first direction during setting of the dose.

A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve, and a drive sleeve. A clutch is configured to permit rotation of the drive sleeve and the dose dial sleeve with respect to the housing when the dose dial sleeve and drive sleeve are coupled through the clutch. Conversely, when the dose dial sleeve and drive sleeve are in a de-coupled state, rotation of the dose dial sleeve with respect to the housing is permitted and rotation of the drive sleeve with respect to the housing is prevented. In the de-coupled state, axial movement of the drive sleeve transfers force in a longitudinal direction for actuation of a drug delivery device.

The present disclosure relates to a drug delivery device, comprising a housing, a cartridge, the cartridge containing a drug in a quantity sufficient for a plurality of doses of the drug, a bung, the bung being movably retained within the cartridge to dispense a dose of the drug from the cartridge upon movement of the bung with respect to the cartridge, and a drive mechanism, the drive mechanism being operable to transfer a driving force to the bung to dispense the dose of the drug from the cartridge. The drug delivery device is configured such that the maximal driving force which is transferrable to the bung via the drive mechanism varies and is adjusted to the current position of the bung within the cartridge.

A geared drive arrangement comprises a stationary portion and a drive rod defining a reference axis and during operation being arranged to rotate and be moved axially corresponding to the reference axis, the drive rod comprising a first thread and a second thread. The drive arrangement further comprises a drive member comprising a drive thread in engagement with the drive rod first thread, and a nut portion comprising a propulsion thread arranged rotationally locked relative to the stationary portion and in engagement with the drive rod second thread. The drive member is arranged to rotate corresponding to the reference axis during operation, with the threaded engagement between the drive member and the drive rod causing the drive rod to rotate, and the threaded engagement between the nut portion and the drive rod causing the drive rod to move in the distal direction.

A dosing device for an injection device, the dosing device including an actuating element for adjusting and/or dispensing a dose from the injection device, a thrust element for generating a forward movement for discharging a dose and a coupling to which the actuating element and the thrust element are coupled such that a rotational movement of the actuating element is transmitted directly to the thrust element and an axial movement of the actuating element is different than an axial movement of the thrust element.

A drug delivery device comprises an housing, an axially displaceable piston rod, a rotatable drive member, a spring housing, a torsion drive spring coupled to the spring housing respectively the drive member, dose setting means allowing a user to simultaneously set a dose amount to be expelled and strain the torsion drive spring correspondingly by rotation of the drive member, and a release member being axially moveable relative to the housing between a proximal initial position and an actuated distal release position. The spring housing is helically coupled to the housing such that the spring exerts a tangential force on the spring housing to thereby bias the spring housing in the proximal direction, whereby the spring housing thereby exerts a proximally directed biasing force on the release member. The spring housing can be moved helically in the distal direction when a distally directed force is exerted on the release member.

A dose setting mechanism for a drug delivery device includes a primary drug delivery assembly and a secondary drug delivery assembly. The dose setting mechanism includes a primary dose dial component for setting a dose in the primary drug delivery assembly and a secondary dose dial component for setting a dose in the secondary drug delivery assembly. The primary dose dial component and the secondary dose dial component are configured to rotate during dose setting. A gear mechanism is configured such that in a first phase of the dose setting, rotation of the primary dose dial component is transferred to the secondary dose dial component and such that in a second phase of the dose setting, the secondary dose dial component is decoupled from the primary dose dial component such that rotation of the primary dose dial component is prevented from being transferred to the secondary dose dial component.

Described herein are injection devices capable of automatically injecting substances into the soft tissue of a patient. The devices can inject low to high viscosity materials at predetermined, user selected injection rates, allowing the operator more control than a traditional syringe. The devices can allow mixing of more than one substance and/or reconstitution of a solid substance for injection. The injection devices described herein can allow the operator to easily inject one or more low to high viscosity liquid or gel soft-tissue augmentation fillers, one or more drugs, one or more other biocompatible materials, or combinations thereof.

An ambulatory infusion device including a pump drive unit, a valve drive unit and a control unit. The pump drive unit includes a pump actuator and a pump driver coupled to a piston of a metering pump unit. The valve drive unit includes a valve actuator and a valve driver coupled to a valve unit for transmitting a valve switching force or torque. The control unit controls a repeated execution of: (a) placing the valve unit in a filling state; (b) displacing the piston in a retraction direction; (c) displacing the piston in an advancing direction by a backlash compensation distance; (d) switching the valve unit from the filling state into a draining state; and (e) further displacing the piston in the advancing direction in a number of incremental steps over an extended time period.