An injection assembly includes a housing with a barrel positioned within the housing. The barrel includes an axis extending from a proximal end to a distal end thereof and a chamber for storing medicine. An elongate anti-rotation shaft is rotationally fixed to the housing and has a non-circular cross-section. The injection assembly includes an inner screw having an inner screw opening to complementarily receive the anti-rotation shaft to prevent rotation of the inner screw with respect to the anti-rotation shaft but allow respective linear translation along the axis. An outer screw is positioned within, and rotatable with respect to, the housing and has an outer screw opening to threadably receive the inner screw, wherein rotation of the outer screw translates the inner screw along the axis and along the anti-rotation shaft. A plunger is coupled to the distal end of the inner screw and is moveable with respect to the chamber to push the medicine out of the chamber when the outer screw is rotated.

A drive mechanism for a drug delivery device having a rotationally fixed plunger rod driven by a lead screw. The lead screw engages a free lock which is coupled to a release knob. A dose setting dial cooperates with an inner cylinder using a clutch to establish the axial movement of the plunger rod during dose setting and dispensing.

An assembly for a drug delivery device comprises a housing, a dose member which is displaceable in a proximal direction with respect to the housing for setting of a dose of a drug, a clutch member which is displaced in the proximal direction with respect to the housing when setting the dose, and a stop member configured to define a clutch stop position. The clutch member and the dose member are configured to mechanically cooperate with one another when the clutch member is in the clutch stop position, thereby preventing further displacement of the dose member in the proximal direction with respect to the housing during setting of the dose.

The present disclosure relates to a medication delivery device having a dose detection system and an associated control system configured to determine an amount of medication delivered from the medication delivery device based on the sensing of relative rotation within the medication delivery device. The relative rotation may occur between a dose setting member and an actuator and/or housing of the medication delivery device. The rotation sensing may involve piezoelectric sensing, more specifically repeatedly deforming a piezoelectric sensor with a mechanical force. The dose detection system may be a modular or integral component of the medication delivery device.

Syringe attachments and syringes have particular suitability to the precision dispensing of small amounts of high viscosity materials, such as dermal fillers. Syringes and attachments may include precision position indicators viewed from multiple positions to enable a user to determine plunger position and the amount of dispensed contents with precision. A configuration of the attachment may be slidably secured to a syringe to permit a user to operate the syringe from a lateral position using sliding movement of the thumb and fingers of one hand, for example. This configuration may be particularly suitable for self-administered insulin injections.

A drive mechanism for a drug delivery device having a rotationally fixed plunger rod driven by a lead screw. The lead screw engages a free lock which is coupled to a release knob. A dose setting dial cooperates with an inner cylinder using a clutch to establish the axial movement of the plunger rod during dose setting and dispensing.

A drive mechanism for a drug delivery device having a rotationally fixed plunger rod driven by a lead screw. The lead screw engages a free lock which is coupled to a release knob. A dose setting dial cooperates with an inner cylinder using a clutch to establish the axial movement of the plunger rod during dose setting and dispensing.

An autoinjector includes a case adapted to hold a medicament container having a needle, a needle shroud slidably disposed in the case and translatable between an extended position relative to the case in which the needle is covered and a retracted position relative to the case in which the needle is exposed, and a plunger slidably disposed in the case. The case includes a rib. The plunger includes a plunger boss adapted to abut the rib and the needle shroud when the needle shroud is in the extended position and disengage the rib when the needle shroud is in the retracted position to allow the plunger to translate axially relative to the case.

In some embodiments, a delivery device includes a device actuator and a cannula portion through which a therapeutic substance is ejected. The cannula portion includes an outer shaft, a needle that is configured to move through the outer shaft, and a plunger that is configured to move through the needle, forming a positive displacement arrangement.

A drug solution injection device includes: a catheter that has a hollow shaft, a hollow needle portion disposed on a distal end of the hollow shaft, and a lumen formed inside each of the hollow shaft and the needle portion and containing a drug solution; and a wire that is inserted into the lumen and is advanced from a proximal end of the lumen toward a distal end side so as to discharge the drug solution in the lumen from a distal end of the needle portion.