An apparatus for a firing mechanism for use in an injection device and including: a rear cap having an elongate member extending axially forwards when installed within the injection device; a plunger releasably connected, directly or indirectly, to the elongate member and, upon release of the connection to the elongate member, axially displaceable in a forward direction; and a plunger driver to drive the plunger axially forwards upon release of the connection to the elongate member, wherein the plunger and the rear cap define an axial length of the assembly, which in turn determines a start position of a forward end of the plunger before release of the connection to the elongate member, and wherein, during construction of the assembly, the plunger is releasably connectable, directly or indirectly, to the elongate member at one of a plurality of positions for controlling the axial length of the assembly.

The invention provides an adaptor for a medicament delivery device is configured to enable a set dosage of a medicament to be drawn into and/or expelled from the device, the adaptor including: a body configured to be coupled to the device; an attachment portion movable with respect to the body and configured for attachment with a first part of the device; an engaging portion movable with the attachment portion; and a receiver configured to receive a movement constraint guide (MCG) and facilitate engagement between the engaging portion and the MCG; wherein the MCG includes one or more physical features defining at least an aspect of the set dosage; and wherein activation of said first part of the device to draw and/or expel the medicament is stopped when the set dosage is reached by engagement between the engaging portion and at least one of the one or more physical features of the MCG. The invention thus allows ready control of one or more aspects of dosage administration, which can be the amount of a dose and/or or the repeats of a dose.

A connector for coupling a container carrying a medical fluid to a vascular access device may include a housing comprising and inner surface defining an internal chamber comprising a fluid channel disposed in the internal chamber. The fluid channel may include a pair of oppositely positioned cutouts. The connector may further include a slider disposed and supported in the internal chamber and having an internal compartment and an aperture through inner walls of the internal compartment. The slider may be reciprocally movable between (i) a first position, where the aperture of the slider is axially aligned with the pair of cutouts to allow the medical fluid to flow through the outlet, and (ii) a second position where the aperture of the slider is not aligned with the pair of cutouts and the inner walls of the slider blocks fluid connection between the slider and the fluid channel.

A drive unit for an injector includes an elastomeric drive member configured to possess a first elastic potential energy in an elastically stretched state that is releasable to convert the elastic energy to a first biasing force. A selectively releasable plunger rod has a locked position maintaining the elastomeric drive member in the elastically stretched state. A trigger member is biased by a second biasing force into an interlocking position. In the interlocking position, an arm of the trigger member interlocks with a notch of the plunger rod, thereby maintaining the plunger rod in the locked position thereof. The trigger member is selectively movable against the second biasing force to an unlocking position spaced from the notch, thereby releasing the first elastic potential energy into the first biasing force to axially advance the plunger rod and thus advance the piston through the reservoir.

Apparatus and methods for providing controlled pressure-flow pulses which purge a catheter system with turbulent flow flushing. Accomplishment of such controlled pressure-flow pulses is provided by a variety of inventive devices including a special plunger rod for a conventional syringe, other interactive parts for conventional syringes, an in-line catheter attachable device which automatically generates the controlled pressure-flow pulses and also single pulse, digitally operated devices.

An injection device is disclosed wherein a dose can be set by rotating a dose setting member, whereby a push button is elevated from one end of the device a distance proportional to the set dose from a position fixed relative to the housing, and wherein the set dose can then be injected by pressing the push button back to its non-elevated position, through which motion a screw will move approximately the same distance or a smaller distance. The invention provides a method of reducing the dose force and/or the push-button movement during injection.

The present invention relates to a drug delivery device that houses a piston equipped cartridge and a drive mechanism comprising a piston rod (170) configured for axially moving the piston in a distal direction. An adjustment member (150) connects to the member (150) comprises a first contour system (175) defining a plurality of steps (175′, 175″, 175′″) being circumferentially disposed and arranged axially offset from one another. The other of the piston rod (170) and the adjustment member (150) comprises at least one radially disposed protrusion (155). For eliminating an axial clearance between the piston rod (170) and the piston of the cartridge the at least one radially disposed protrusion (155) axially engages a selective one of said plurality of steps (175′, 175″, 175′″) so that the relative rotational position between the piston rod (170) and the adjustment member (150) is decisive for the axial position of the adjustment member (150) relative to the piston rod (170).

Plunger rod stops attach to existing syringes to limit the range of motion of the plunger, thereby to precisely control the amount of liquid that can be expelled from the syringe when the plunger rod stop is in place. In some embodiments, plunger rod stop devices generally include a body configured to attach to the plunger, and a stand-off extending from the body, configured to contact the finger flange when the plunger is depressed. In other embodiments, the plunger rod stop attaches to the finger flange or other fixed component of the syringe and the stand-off is configured to contact the plunger or plunger rod. Methods of the invention involve using the devices to interfere with the range of motion of the plunger, then reconfiguring or removing the device to allow the plunger to be moved a predetermined length, which corresponds to a precise dosage amount.

The present invention relates to an innovative system which definitively prevents the re-use of syringes with retractable needles, allowing at the same time to fill the tank by means of a mechanical system installed inside the piston. The operation that aims at preventing the re-use of the device takes place through a mechanical system that prevents the return of the piston towards the initial position of aspiration and restricts, therefore, its action in a single direction and prevents the return of the plunger to the initial position of injection and therefore restricts its action in a single direction. Moreover a rotating mechanical transition system prevents the repositioning of the piston in the previously used position. The filling of the container, instead, takes place through the use of a system via a flexible cannula placed inside the piston.

A dosage sensing module for or in a pen drug delivery device and a method of assembling the same. The module comprises a housing consisting of a first and second housing part, a power source unit, a processor unit and a dosage sensor unit with a first sensor part adapted to be fixed to a part not rotating during dose expelling and comprising a printed circuit board on which a pattern of individual electrical conductive sensor areas are arranged. The sensor unit further comprises a second sensor part adapted to be fixed to the piston rod to follow the rotation thereof during dose expelling. The second sensor part comprises individual structures that together with the conductive sensor areas are adapted to, upon relative rotational movement between the first and second sensor part, provide electrical signals to a processor unit indicative of the relative rotational position between the first and second sensor part.