.[.An auto-injector for administering a dose of a liquid medicament (M) comprises of a substantially cylindrical housing arranged to contain a pre-filled syringe with an injection needle, a plunger and a stopper for sealing a syringe barrel and a drive means releasably coupled to the plunger for advancing the syringe in the proximal direction (P) for needle insertion into an injection site and for displacing the dose of medicament (M) into the injection site. The drive means is arranged to be decoupled from the plunger for advancing a needle shroud to a safe position (PS) to surround the injection needle after the injection. According to the invention, the drive means bears against a thrust collar arranged to be releasably coupled to the plunger through a ramped engagement of a first tongue and a first recess so as to rotate the thrust collar on translation in proximal direction (P). At least one longitudinal gap (G1, G2) is provided for guiding at a first and/or second protrusion of the thrust collar to prevent a rotation of the thrust collar. A circumferential gap (G3) is arranged to allow the thrust collar to rotate out of engagement to the plunger on removal of the auto-injector from the injection site..]. .Iadd.An auto-injector includes a housing, a thrust member comprising a radial projection configured to engage a ramped surface within the housing when the thrust member is in a first rotational position and to disengage from the ramped surface when the thrust member is moved to a second rotational position, a drive spring disposed within the housing, and a needle shroud configured to (i) inhibit rotation of the thrust member when the needle shroud is in an extended positon and the thrust member is in the first rotational position, (ii) allow the thrust member to rotate from the first rotational position to the second rotational position when the needle shroud is in a retracted positon, and (iii) permit the thrust member, after the thrust member has been rotated to the second rotational position, to be moved axially by the drive spring..Iaddend.

A catheter insertion device includes a housing, a needle, a guide wire, and a catheter disposed coaxially over the needle. The needle has a proximal end in the housing and a distal end extending from a distal end of the housing in an insertion position. The guide wire has a distal portion disposed in a lumen of the needle in a withdrawn position. The guide wire may include a safety tip having a non-coiled configuration in the withdrawn position and a coiled configuration in an advanced position. The catheter insertion device may include a sliding member attached to the guide wire, wherein movement of the sliding member translates the guide wire from the withdrawn position to the advanced position.

An autoinjector for dispensing a liquid product includes a housing; a product container arranged in the housing, particularly, a syringe comprising a displaceable piston; a drive member; a first spring which acts on the drive member and the piston to dispense the product from the container; signal element releasably axially coupled with the drive member so that the signal element is transported in the dispensing direction as said drive member is displaced; and a second spring, which exerts a spring force on the signal element against the dispensing direction and is tensioned as the signal element is transported in the dispensing direction. When the signal element is released or detached from the axial coupling, the second spring causes the signal element to accelerate opposite the dispensing direction and strike against a signal stop and generate an acoustic and/or tactile signal.

A method for treating a patient using a catheter insertion device. The catheter insertion device includes a housing, a needle, a catheter, a guidewire, and an actuator mechanism. The needle is attached to a needle carrier, the catheter is positioned coaxially around the needle such that a distal end of the needle extends distal of a distal end of the catheter, and the guidewire has a distal end positioned in a lumen of the needle. The method includes holding the catheter insertion device, inserting the distal end of the needle and catheter into a blood vessel, advancing the distal end of the guidewire out of the lumen of the needle into the blood vessel, moving the catheter over the guidewire in the blood vessel, and activating the actuator mechanism to simultaneously retract the distal end of the needle and the distal end of the guidewire into the housing.

The present invention relates to a pre-filled disposable injection device and a needle cannula in combination. The prefilled disposable injection device (1) is made from a housing (2) containing a non-exchangeable cartridge (10) for storing a liquid drug sufficient for a number of injections. The proximal end of the pre-filled injection device (1) carries the dose setting button (3) and the distal end carries the needle cannula (20) having a lumen (21) through which the settable dose is expelled. The distal end (23) of the needle cannula (20) is covered by a telescopic needle covering shield (30) which shield (30) can operate between a first position covering the tip (24) of the needle cannula (20) and a second retracted position allowing an injection to be performed. The shield (30) carries a cleaner (50) which cleans at least the tip (24) of the needle cannula (20) between successive injections such that the prefilled injection device can be used without changing the needle cannula (20) during its life cycle.

An injector includes a trigger mechanism including: a trigger member disposed about an axis having an aperture and a protrusion, and a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom, the ram assembly further having a trigger engagement member configured to engage the aperture of the trigger member when the trigger member is in a pre-firing condition; an energy source associated with the ram for powering the ram to expel the medicament; and a user-operable firing-initiation member having an aperture engaged with the protrusion of the trigger member and operable for causing an axial translation of the trigger member in a proximal direction from the pre-firing condition to a firing condition in which the trigger engagement member is released from the retaining portion to allow the energy source to fire the ram.

The present disclosure relates to a medicament injection device comprising a housing, a cartridge holder mounted in the housing and configured to receive a cartridge containing a medicament, an injection needle having a proximal end and a distal end, an injection needle holder to which the injection needle is fixed. The medicament injection device comprises an actuating mechanism for pivoting the injection needle holder relative to the cartridge holder between a storage position in which, when the cartridge is received in the cartridge holder, the distal end of the injection needle is spaced from the cartridge, and a use position in which, when the cartridge is received in the cartridge holder, the distal end of the injection needle can engage the cartridge.

The invention relates to an autoinjector 59 for administering a fluid medicament to a subject comprising: a housing 1 for receiving a cartridge holder; a driver assembly 8; the driver assembly on actuation may move the cartridge 3 forward in the cartridge holder 2; a needle cover 4 may be coupled to the housing wherein the needle cover 4 travels in a linear or translational movement; said needle cover 4 is adapted to protect a needle when the needle cover may be in first locking position 17 and second locking position 18; the linear or translational movement may be achieved by a cam profile 13 and a cam follower 14; the cam profile 13 may be provided on outside surface of housing and the cam follower 14 located between the needle cover 4 and the housing 1; a first biasing member 15; and a second biasing member 16 configured to bias the cartridge 3 and the needle cover 4 respectively; and a safety cap 11 to control the actuation of the autoinjector.The needle cover 4 further comprises a sleeve 91 or sleeve 92 which prevents or inhibits the obstruction of the movement of needle cover 4 when the user accidentally hold the needle cover 4 during actuation of the autoinjector.

A rotational locking type safety insulin pen needle includes a needle body, intermediate shield, front shield, tail cover and rear spring, wherein: the intermediate shield provides a rotating tube, the tube provides a beveled rail on the outer edge; the front shield provides a bevel acting part on the inner edge; the tail cover provides an elastic leg, the leg provides a front protection stopper; the rotating tube provides a first and second rail slot at intervals along the circumferential direction. The backward movement of the front shield when the needle is pushed to drive the rotation of the rotating tube and uses the coordination of the first and second rail slot on the rotating tube and the rear protection stopper on the tail cover to change the coordination relationship between the tail cover and the rotating tube, which provides the reliable locking protection of the tail cover after use.

A rotational locking type safety insulin pen needle comprises a needle body, intermediate shield, front shield and a spring, wherein the intermediate shield has a rotating tube with a beveled rail on the outer edge; the front shield has a bevel acting part on the inner edge; the rotating tube has an elastic arm in the front with a front protection stopper; relative to the front protection stopper, the front shield has a guiding and a limit slot at intervals along the circumferential direction. The backward movement of the front shield when the needle is pushed to drive the rotation of the rotating tube and uses the coordination of the front protection stopper on the rotating tube with the guiding and limit slot on the front shield to change the coordination relationship between the front shield and the rotating tube, which provides the reliable locking protection of the front shield.