A drug injection device (10) including a housing (12) for holding a container (20) having a needle (24) for penetrating skin and a plunger (42) for expelling a drug stored in the container. The device includes visual and/or audible indicators for indicating that the correct depth of needle penetration has been achieved and that drug injection/extrusion has been started and/or completed. The device may further include a label (140) for visually confirming the quality of the drug contained therein. Alternatively, a tray (110) may be provided for receiving the drug injection device, which allows the quality of the drug contained therein to be visually confirmed.

A protective assembly includes a body for receiving the syringe; and a coupling device inside the body, rigidly connected to the barrel as regards to axial movement relative to the body. The coupling device includes an attaching element which can be either in an engaged state to axially fix the coupling device and the plunger rod, or in a release state in which the coupling device and the plunger rod are axially free relative to one another. The coupling device is axially movable in the body from a storage position to an injection position in which the needle extends beyond the body, and in which the attaching element can move towards the release state. The coupling device is axially movable in the body from the injection position towards a safety position, in which the needle is covered by the body.

A medicament delivery device comprising: a first component, and a second component arranged concentrically with the first component, wherein the second component is configured to move axially relative to the first component from a first position to a second position, wherein one of the first component and the second component has a radially extending flash, wherein the other one of the first component and the second component has a chamfer aligned with and facing the flash when the second component is in the first position, and wherein one of the chamfer and the flash is configured to contact and subsequently pass the other one of the chamfer and the flash when the second component is moved from the first position towards the second position to thereby facilitate movement of the second component.

Described is a medicament delivery device (1), comprising a body (2), a container carrier (7) for retaining a medicament container within the body (2) and being slidably disposed in the body (2), a sleeve (6) slidably coupled to body (2), and a piston rod (11) coupled to the body (2) and the container carrier (7). The piston rod (11) and the container carrier (7) provide a feedback as 10 the container carrier (7) moves from a first position (P1) to a second position (P2) relative to the body (2).

A drug delivery device configured to provide a dose of medicament is disclosed. The drug delivery device includes a main housing, a syringe arranged in the main housing, and a pneumatic power pack arranged in the main housing. The pneumatic power pack includes a pressurized gas source storing pressurized gas, a valve for the pressurized gas source, a sleeve having an inner wall, and a plunger. The sleeve is configured to receive pressurized gas released from the pressurized gas source. The plunger is in sliding gas-tight engagement with the inner wall of the sleeve. Upon activation of the valve, the valve releases the pressurized gas, and the released pressurized gas flows into the sleeve and propels the plunger in a distal direction with respect to the sleeve and the syringe, so as to eject medicament from the syringe.

AUTO-INJECTOR ASSEMBLY The auto-injector assembly (100) includes a housing (102), a syringe assembly (202) to store a predetermined volume of a drug to be administered, a needle guard (212) to surround the syringe assembly (202) such that a portion of the needle guard (212) is adapted to extend out of the housing (102) in an initial state and to retract into the housing (102) when the portion is pressed on to an injection site, a spring holder (218) to hold a dose delivery spring (216) in a compressed state, locking unit (220) to keep the spring holder (218) in a locked state, and a plunger (222) engaged with the spring holder (218) and adapted to move towards the syringe assembly (202) when the spring holder (218) is unlocked. A position of engagement of the plunger 222) with the spring holder (218) is adapted to change for controlling a travelling distance of the plunger (222) within the housing (102) based on the predetermined volume of the drug in the syringe assembly (202).

In an embodiment provided herein, an injection simulation device including a housing having a proximal end and a distal end is provided. The injection simulation device embodiment comprises a plunger having a proximal end, a distal end and being slidable relative to the housing, and a retractable injection simulation member at the distal end of the housing, at least one biasing member associated with the retractable injection simulation member and associated with the plunger, wherein a first force on a distal end of the injection simulation member causes movement of the injection simulation member from an extended position to a retracted position, to compress the first biasing member, and simulate the tactility of an injection to a user; and wherein a second force on the proximal end of the plunger asserts a third force on the first biasing member to facilitate resetting the injection simulation member to the extended position.

A syringe includes a dosage setter operatively coupled to a plunger rod and comprising a rotatable body that comprises a set of one or more stops for engaging the set of one or more protrusions of the plunger rod depending on at least a rotational position of the set of one or more stops relative to the set of one or more protrusions, wherein a first rotational adjustment associated with the dosage setter is configured to set a first dosage increment by adjusting a relative axial position between the rotatable body and the plunger rod, and a second rotational adjustment associated with the dosage setting assembly is configured to set a second dosage increment that is larger than the first dosage increment by adjusting a relative rotational alignment between the set of one or more stops and the set of one or more protrusions.

An autoinjector includes a case adapted to hold a medicament container having a needle, a needle shroud telescopically coupled to the case, and a plunger rotationally and slidably disposed in the case. The needle shroud is movable between a first extended position relative to the case in which the needle is covered and a retracted position relative to the case in which the needle is exposed. The plunger is rotatable relative to the case between a first rotational position in which the plunger is engaged to the case and a second rotational position in which the plunger disengages the case. The needle shroud is operably coupled to the plunger. When the needle shroud translates from the first extended position to the retracted position, the plunger rotates from the first rotational position to the second rotational position.

A medicament delivery device system for delivery of a medicament from a cartridge (10). The system comprises a first container (11) for storage of a first substance, a second container (12) received in the first container (11) for storage of a second substance, and valve means (68) for closing a distal end of the second container (12). The system further comprises a disposable cassette (102) and a reusable firing unit (200). The cassette (102) has a body (104) for receiving the cartridge (10), and a mixing element (148) for displacing the second substance into the first chamber (16) in a mixing stroke, to mix with the first substance to form the medicament. The firing unit (200) comprises a drive element (208) for expelling the medicament from the first chamber (16) in a delivery stroke and a trigger arrangement (240) for initiating the delivery stroke.