Provided is an injection device for injecting a substance, comprising a case receiving a barrel containing the substance to be injected and comprising a stopper movable inside the barrel, a plunger unit comprising a triggering portion, the plunger unit being coupled to the stopper and movable with regard to the case from an initial, proximal position to a final, distal position to inject the substance when the barrel is provided into the case, an end-of-dose indicator movable from a hidden position to a visible position in which at least one portion of the end-of-dose indicator is visible to a user, hiding means for locking the end-of-dose indicator in the hidden position and configured to be unlocked by the triggering portion of the plunger unit when the plunger unit reaches an indicator position.

Provided are ergoline derivative containing medicaments disposed within a preassembled, prefilled, single-use delivery device, methods for administering a medicament using a preassembled, prefilled, single-use delivery device, and systems or kits that contain one or more preassembled, prefilled, single-use devices and user instructions, such as for treatment of a migraine or other headache.

The passive safety device comprises a sleeve having a proximal end configured to be secured to a distal tip of the injection device, a hub slidably mounted onto the sleeve between a pre-use position, an injection position wherein the hub is proximally located with regard to the pre-use position, and a safety position wherein the hub is distally located with regard to the injection position, a biasing element configured to urge the hub distally towards the safety position, and a protector configured to slide together with the hub relative to the sleeve between the pre-use position and the injection position. The safety device further comprises first blocking means configured to block a distal movement of the protector when the hub is in the injection position so that the protector is prevented from sliding back together with the hub in a distal direction.

Provided is an injection device, comprising a syringe comprising a needle, a barrel, a stopper in sliding engagement inside the barrel, a plunger unit moveable with regard to the barrel, a case accommodating the barrel and provided with elastic means and an operating stop, and a needle shield adapted to be moveable under the force of the elastic means from an injection position to a safety position, and provided with a shield stop, wherein the operating stop is configured to prevent the needle shield to move to the safety position by abutting against the shield stop, wherein the plunger unit comprises a triggering portion configured to deflect the flexible leg of the needle shield when the plunger unit has reached a triggering position during its injection movement.

A medicament delivery device includes a housing having a longitudinal axis, a container holder, an axially movable plunger adapted to be displaced along the longitudinal axis into the container holder, and an energy accumulating member arranged inside the housing and adapted for displacing the plunger along the longitudinal axis. The plunger includes an outer plunger rod and an inner plunger rod arranged at least partially inside the outer plunger rod, the inner plunger rod being threadedly engaged with the outer plunger rod and manually rotatable to displace the inner plunger rod along the longitudinal axis into the container holder.

Disclosed is a method for controlling an auto injector and an auto injector for administering a medicament from a cartridge having a first cartridge end and a second cartridge end and having a cartridge outlet at the first cartridge end, the cartridge comprising a cartridge compartment with a first cartridge subcompartment containing a first medicament component of the medicament and a second cartridge subcompartment containing a second medicament component of the medicament. The auto injector comprises: a housing; a cartridge receiver; a cartridge sensor; a drive module; an orientation sensor; and a processing unit.

A jet injector that includes a prefilled syringe. The syringe includes a fluid chamber that contains a medicament. The syringe also has an injection-assisting needle, and a plunger is movable within the fluid chamber. A housing is configured for allowing insertion of the needle to a penetration depth. The housing includes a retractable guard and an interference component, e.g., a lock ring, adjacent to the retractable guard that interferes with the movement of the retractable guard. An energy source is configured for biasing the plunger to produce an injecting pressure to jet inject the medicament from the fluid chamber through the needle to an injection site.

An injection device includes a lower housing, a needle guard and an upper housing. With the upper housing in a pre-use position and the needle guard in a first position, an abutment body of an arm of the upper housing abuts a catch of the lower housing, preventing the upper housing from moving distally relative to the lower housing toward a dispensed position. Proximal movement of the needle guard from the first position to a second position thereof causes proximal movement of a camming ramp of a leg of the needle guard with respect to the catch and the abutment body such that the camming ramp engages the arm, thereby deflecting the abutment body radially outwardly by a distance sufficient to allow the abutment body to pass radially outside of the catch, and, in turn, permits distal movement of the upper housing into the dispensed position of the upper housing.

An autoinjector includes a case adapted to hold a medicament container having a needle, a needle shroud telescopically coupled to the case, and a plunger rotationally and slidably disposed in the case. The needle shroud is movable between a first extended position relative to the case in which the needle is covered and a retracted position relative to the case in which the needle is exposed. The plunger is rotatable relative to the case between a first rotational position in which the plunger is engaged to the case and a second rotational position in which the plunger disengages the case. The needle shroud is operably coupled to the plunger. When the needle shroud translates from the first extended position to the retracted position, the plunger rotates from the first rotational position to the second rotational position.

An autoinjector includes a pre-filled syringe arranged within a housing of the autoinjector, a needle shield covering a needle of the pre-filled syringe in a storage state of the autoinjector, an axially moveable needle guard arranged to cover the needle of the pre-filled syringe at least after use of the autoinjector and to move relative to the pre-filled syringe during use of the autoinjector, and a removable cap in which the needle guard is stored in the storage state of the autoinjector, Upon removal of the cap, the needle shield is also removed from the autoinjector.