Systems are described for conducting minimally invasive medical interventions utilizing instruments and assemblies thereof to stabilize and/or fixate a dysfunctional sacroiliac (SI) joint. The systems include a drill guide adapted to create a pilot SI joint opening in the dysfunctional SI joint through an incision comprising a length no greater than 3.0 cm; portions of the pilot SI joint opening being disposed in the sacrum and ilium bone structures. The drill guide includes a tri-mode fixation system adapted to position and stabilize the drill guide during creation of the pilot SI joint opening in the dysfunctional SI joint and delivery of the SI joint prosthesis therein. The systems also include a SI joint prosthesis configured to be inserted into the pilot SI joint opening of the dysfunctional SI joint, and a prosthesis deployment assembly configured to engage the SI joint prosthesis and advance the SI joint prosthesis into the dysfunctional SI joint.

Methods are described for conducting minimally invasive medical interventions utilizing instruments and assemblies thereof to stabilize and/or fixate a dysfunctional sacroiliac (SI) joint. The methods include the initial steps of providing a drill guide assembly adapted to create a pilot opening in the dysfunctional SI joint, a prosthesis configured to be inserted into the pilot opening created by the drill guide assembly and a prosthesis deployment assembly adapted to engage and advance the prosthesis into the pilot opening in the dysfunctional SI joint. The drill guide assembly includes a drill guide having a prosthesis access opening therethrough; the opening having a configuration that corresponds to the shape of the prosthesis. In some aspects of the invention, the methods thus include the step of advancing the prosthesis through the drill guide and then into the pilot opening in the dysfunctional SI joint with the prosthesis deployment assembly; the initial advancement of the prosthesis through the drill guide providing consistent, optimal placement of the prosthesis in the dysfunctional SI joint.

Configurations are described for conducting minimally invasive medical interventions utilizing elongate instruments and assemblies thereof to stabilize and/or fixate a sacro-iliac joint. In one embodiment, a tool assembly may be advanced from a posterior approach into the SI junction and configured to create a defect defined at least in part by portions of both the sacrum and the ilium, the defect having a three dimensional shape defined in part by at least one noncircular cross sectional shape in a plane substantially perpendicular to the longitudinal axis of the tool assembly. After a defect is created, the tool assembly may be retracted and a prosthesis deployed into the defect.

An insertion assembly may include a flexible tool and a DTS guide configured to engage an intervertebral spacer having a fastener channel oriented at a first angle. The DTS guide may include a DTS guide channel oriented at the first angle which may be aligned with the fastener channel. The flexible tool may include a flexible shaft and a working member disposed at a distal end of the flexible shaft. The working member may be received through the DTS guide channel at the first angle. At least a portion of the flexible shaft adjacent the DTS guide member may flex while the working member is received through the DTS guide channel, such that a distal portion of the flexible shaft may be at a greater absolute angle relative to a DTS guide shaft than a proximal portion of the flexible shaft.

An intervertebral spacer assembly may include a first intervertebral spacer with a superior surface configured to engage a superior vertebral body, an inferior surface configured to engage an inferior vertebral body, and a proximal surface with a first fastener channel. The assembly may further include a first fastener and a locking member with a first anti-backout member. The first intervertebral spacer or the locking member may have a locking member channel. The other may have a compressible collet insertable into the locking member channel to couple the locking member to the first intervertebral spacer such that the locking member is rotatable relative to the first intervertebral spacer between an unlocked position in which the first anti-backout member does not obstruct the first fastener channel, and a locked position in which the first anti-backout member obstructs the first fastener channel to retain the first fastener in the first fastener channel.

Configurations are described for conducting minimally invasive medical interventions utilizing elongate instruments and assemblies thereof to stabilize and/or fixate a sacro-iliac joint. In one embodiment, a tool assembly may be advanced from a posterior approach into the SI junction and configured to create a defect defined at least in part by portions of both the sacrum and the ilium, the defect having a three dimensional shape defined in part by at least one noncircular cross sectional shape in a plane substantially perpendicular to the longitudinal axis of the tool assembly. After a defect is created, the tool assembly may be retracted and a prosthesis deployed into the defect.

Prostheses are described for stabilizing dysfunctional sacroiliac (SI) joints. The prostheses are sized and configured to be press-fit into surgically created pilot SI joint openings in dysfunctional SI joint structures. The prostheses include a polymer composition comprising poly (glycerol sebacate) (PGS). The polymer composition can also include selective biologically active agents, such as a bone morphogenic protein (BMP), and/or a pharmacological agent, such as an antibiotic.

Prostheses are described for stabilizing dysfunctional sacroiliac (SI) joints. The prostheses are sized and configured to be press-fit into surgically created pilot SI joint openings in dysfunctional SI joint structures. The prostheses include a fixation composition that is adapted to transition from a flowable state, wherein the fixation composition flows into spaces between the prostheses and the dysfunctional SI joint structures when the prostheses are implanted in a dysfunctional SI joint, to a solid elastomer state upon application of radiation energy, wherein the fixation composition forms a positive fit connection by and between the prostheses and the dysfunctional SI joint structures.

Shoulder arthroplasty systems and configurations for components thereof are described. For example, implant systems for a total should arthroplasty (TSA), hemi shoulder arthroplasty, and reverse should arthroplasty (RSA) are described. In addition, exemplary configurations for baseplates, glenoid components, glenosphere components, humeral components, humeral head components, humerosocket components, connectors, and adaptors, are described.

An intervertebral spacer may include a fastener channel configured to receive a fastener, a locking member channel, and a locking member. The locking member channel may include an inner wall and one or more inner wall engagement features. The locking member may include an anti-backout member, a collet retainable within the locking member channel, and one or more collet engagement features. The locking member may be rotatable within the locking member channel between an unlocked position and a locked position. The one or more collet engagement features may engage the one or more inner wall engagement features in order to retain the locking member in either the unlocked position or the locked position, such that the anti-backout member may selectively obstruct the fastener channel and prevent the fastener from backing out of the fastener channel.