A retractable needle device attachable to the front of a fluid collection or infusion device such as a syringe, the retractable needle device comprising a housing having an engagement member, a slide support surface, a retraction cavity and a first pinch surface; a needle; a needle alignment member comprising a needle tube and a second pinch surface; and a needle retraction mechanism positioned within the needle tube and configured to bias the needle rearwardly; wherein the first and second pinch surfaces are configured so that a pinching force applied to them will cause relative lateral movement between the housing and needle alignment member. This translational movement from an injection position, wherein the needle is aligned with the syringe connector, to a retraction position, wherein the needle is aligned with the retraction cavity, allows the needle retraction mechanism to force the needle into the retraction cavity.

An automatic mixing device, an actuating device having integrated plunger and configured to be removably mounted to the automatic mixing device, and a retractable syringe having the automatic mixing device are provided. The actuating device has an initially compressed spring and a trigger member that is rotatable to initiate spring decompression to drive depression of a mixing plunger seal of the automatic mixing device. Another seal located in an outer chamber of the mixing device is capable of axial movement upon depression of the mixing plunger, from a first position in sealing engagement with one or more apertures in an inner barrel to a second position intermediate the apertures and vents in an outer barrel. This allows depression of the mixing plunger to force a first substance from the outer chamber through the apertures to mix with a second substance in an inner chamber of the inner barrel. The mixed substance in the inner barrel is then delivered by the syringe with subsequent needle retraction.

A device for transferring fluids in a closed system transfer device using flash for last drop extraction and to reduce coring. The device including a piercing member having a distal end and a proximal end and defining a longitudinal fluid channel. A first opening positioned at the distal end of the piercing member wherein the first opening is in fluid communication with the longitudinal fluid channel. A cover or flash positioned over the first opening. The cover including a pre-cut pattern wherein the cover opens along the pre-cut pattern upon application of a distally directed force from the longitudinal fluid channel. The distal end including the first opening having a steep taper to facilitate last drop extraction.

An automatic mixing device, an actuating device having integrated plunger and configured to be removably mounted to the automatic mixing device, and a retractable syringe having the automatic mixing device are provided. The actuating device has an initially compressed spring and a trigger member that is rotatable to initiate spring decompression to drive depression of a mixing plunger seal of the automatic mixing device. Another seal located in an outer chamber of the mixing device is capable of axial movement upon depression of the mixing plunger, from a first position in sealing engagement with one or more apertures in an inner barrel to a second position intermediate the apertures and vents in an outer barrel. This allows depression of the mixing plunger to force a first substance from the outer chamber through the apertures to mix with a second substance in an inner chamber of the inner barrel. The mixed substance in the inner barrel is then delivered by the syringe with subsequent needle retraction.

The auto-injector contains a torsion spring with stored energy for administration of a liquid active substance. It has a housing with a holder for securing an insertable syringe with barrel, sealing plug and needle, the active substance of which it can discharge hydraulically when triggered to do so. The piston in the barrel can be actuated by a pivot lever articulated on a piston slide guided along a rail in the housing. The other end of the pivot lever is articulated on a pivotable leg of a biased torsion spring. By means of the triggered pivoting movement of the biased spring leg, the piston can slide into the syringe in a pivoting phase with a piston slide, and a barb on the piston slide can latch onto the syringe. In a subsequent pivoting movement, the syringe can be retracted into the housing, such that the needle disappears in the housing.

The auto-injector contains a torsion spring with stored energy for administration of a liquid active substance. It has a housing with a holder for securing an insertable syringe with barrel, sealing plug and needle, the active substance of which it can discharge hydraulically when triggered to do so. The piston in the barrel can be actuated by a pivot lever articulated on a piston slide guided along a rail in the housing. The other end of the pivot lever is articulated on a pivotable leg of a biased torsion spring. By means of the triggered pivoting movement of the biased spring leg, the piston can slide into the syringe in a pivoting phase with a piston slide, and a barb on the piston slide can latch onto the syringe. In a subsequent pivoting movement, the syringe can be retracted into the housing, such that the needle disappears in the housing.