Disclosed are a method for preparing an imidazole derivative and crystal form A and crystal form B thereof, and also disclosed is a method for preparing a compound of formula (I) and an intermediate thereof.

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In alternative embodiments, provided are industrial processes and methods for extracting or removing cannabinoids, flavonoids and terpenes from plant materials such as trichomes. In alternative embodiments, the cannabinoids, flavonoids and terpenes are extracted or removed from the plant materials using a non-polar, organic solvent, or a mixture of non-polar, organic solvent and polar, organic solvent.

Various aspects of this patent application relate to methods to separate a cannabinoid molecule from other molecules of a decarboxylated cannabinoid extract.

The invention relates to a processing device in the form of a crystallizer or reactor comprising a tube, at the opposite end regions of which an inlet and an outlet are provided for a crystallization or reaction medium. A helixical web is provided which runs about a longitudinal axis of the tube and which rests against the inner face of the tube casing, and the web is mounted so as to be rotatable about the aforementioned longitudinal axis of the tube. The device also has a drive for rotating the web.

There is disclosed a process for the separation of long chain amino acid and long chain dibasic acid, comprising: (1) adding an ammonium salt to the mixture of alkali salts of long chain amino acid and long chain dibasic acid; (2) heating to remove ammonia; and (3) separating long chain amino acid by solid-liquid separation; and (4) acidifying the salt of long chain dibasic acid with an acid to separate long chain dibasic acid.

Crystal forms I and II of tasimelteon. Crystal form I: an X-ray powder diffraction spectrum using CuK radiation and represented by a 2 angle has diffraction peaks at least at 7.20.2, 7.90.2, 10.60.2, 14.40.2, 15.90.2, 17.30.2, 21.00.2, 23.20.2, and 24.40.2. Crystal form II: an X-ray powder diffraction spectrum using CuK radiation and represented by a 2 angle has diffraction peaks at least at 6.80.2, 12.10.2, 12.50.2, 13.10.2, 13.60.2, 13.80.2, 15.80.2, 17.00.2, 18.40.2, 20.80.2, 24.20.2, and 24.40.2. Crystal forms I and II of tasimelteon have advantages of excellent physicochemical property, good stability and solubility, and simple operation for preparation.

The present invention relates to the extraction of lithium from liquid resources, such as natural and synthetic brines, leachate solutions from clays and minerals, and recycled products.

The present disclosure provides a process for preparing Bortezomib, intermediates, and crystalline forms thereof.

The present invention provides a crystal of reduced glutathione that is stable, and is easy to process, and a method for producing the crystal. According to the present invention, a crystal of a metal salt of reduced glutathione is produced by suspending an amorphous solid of a metal salt of reduced glutathione in a hydrophobic organic solvent, and adding water to the resulting suspension to precipitate a crystal of a metal salt of reduced glutathione.

Disclosed are a method for preparing an imidazole derivative and crystal form A and crystal form B thereof, and also disclosed is a method for preparing a compound of formula (I) and an intermediate thereof. ##STR00001##