There is disclosed a process for the separation of long chain amino acid and long chain dibasic acid, comprising: (1) recovering alkylamine from an aqueous solution of an alkali hydroxide hydrolysis of the mixed amide derivatives by distilling or by extracting with an extractant solvent; (2) cooling the aqueous solution of step (1) to precipitate a mixed alkali salts of long chain amino acid and dibasic acid; (3) recovering the mixed alkali salts of long chain amino acid and dibasic acid to provide a mother liquor; (4) separating long chain amino acid and dibasic acid by acidification-extraction of long chain dibasic acid with an extractant solvent or by selective dissolution of alkali salt of long chain amino acid in an aqueous solvent; and (4) adding an acid to the mother liquor of step (3) to obtain alkanoic acid.

There is disclosed a process for the separation of long chain amino acid and long chain dibasic acid, comprising: (1) cooling the hydrolysis solution to crystallize and separate alkali salt of long chain dibasic acid to provide an aqueous solvent solution; (2) distilling the aqueous solvent solution of step (1) to recover the solvent and to recover alkylamine; (3) cooling the residual solution of step (2) to precipitate and separate alkali salt of long chain amino acid to provide a mother liquor; (4) adding an acid to the mother liquor of step (3) to yield alkanoic acid; (5) adding an acid to an aqueous solution of the alkali salt of long chain dibasic acid of step (1) to obtain long chain dibasic acid; and (6) neutralizing the alkali salt of long chain amino acid of step (3) with an acid to obtain long chain amino acid.

A method for the extraction and isolation of the terpene and isoprenoid compounds from plant material, followed by a centrifugal force induced selective crystallization of isoprenoids resulting in a separation of terpene and isoprenoid fractions. This this method is suitable for the extraction of cannabinoids from Cannabis and the enrichment tetrahydrocannabinolic acid and reduction of tetrahydrocannabinol in an extract. The purity of tetrahydrocannabinolic acid resulting from centrifugal crystallization is such that dissolution and selective recrystallization of tetrahydrocannabinolic acid is possible resulting in >99.9% pure tetrahydrocannabinolic acid, w/w.

The present disclosure is directed to a new and improved separation process that isolates individual minerals from brines containing a mixture of minerals. The brines may be derived from seawater, brackish water, oilfield brines, solution mining, mine run-off, and other sources. Typically, the minerals are recovered as chlorides using a variety of processing steps including evaporation, centrifugation, elutriation, filtration, electrocogulation, crystallization, adsorption, and chromatography.

A method for producing a lithium compound, by which a high purity lithium compound can be produced from low-grade lithium carbonate containing impurities, such as salt water. The method includes: mixing lithium carbonate, an acid containing an organic acid, and water in a reaction tank 1 to produce an aqueous organic acid lithium solution containing an organic acid lithium; mixing the organic acid lithium and a metal hydroxide in a reaction tank 2 to produce an aqueous lithium hydroxide solution; and returning an organic acid, which is regenerated by using an electrochemical device from an organic acid metal by-produced by producing the aqueous lithium hydroxide solution to the reaction tank 1 and using the regenerated organic acid as the organic acid. An apparatus for producing a lithium compound, including the reaction tank 1, the reaction tank 2, the electrochemical device, and a return pipe, which each have a specific function.

Methods, apparatus, and compositions for cleaning gas. The use of segmented multistage ammonia-based liquid spray with different oxidation potentials to remove sulfur compounds from gas. The use of different oxidation potentials may reduce unwanted ammonia slip.

A logging device and method for locating a watered zone in a horizontal well with high watercut problem by isotope labeling is provided. The method successively includes the following operations: a. solidifying an isotope used in an isotope releasing device into a water-soluble carrier; b. connecting the isotope releasing device with a tubing and setting them to a horizontal segment of the well; c. dissolving the water-soluble carriers in the water at the bottom of the well to release the isotope, wherein the releasing rate is proportional to the flow rate of the water; d. starting a lift-up pump and beginning a production logging; and e. continuously performing -ray energy-spectrum analysis on produced water on the ground, so as to locate the watered zone of the horizontal well by the detected species and characteristic content of the isotope, thereby reduces operation risk, saves platform occupying time and logging cost.

The present invention relates to crystalline Form A of obeticholic acid and the preparation method thereof. The present invention provides Form A having characteristic peaks at 2theta value of 4.90.2, 5.20.2, 9.90.2. The present invention provides a novel crystalline form of obeticholic acid, which has good stability, good processability and other favorable properties, and is suitable for storage and usage as a final product. In addition, the preparation method is simple, low cost, and has great value for the future optimization and development of obeticholic acid.

There is disclosed a process for the separation of long chain dibasic acid and fatty acid, comprising: (1) reacting a mixture of long chain dibasic acid and fatty acid with ammonium hydroxide to form an insoluble ammonium salt of fatty acid and a soluble ammonium salt of long chain dibasic acid; (2) recovering the insoluble ammonium salt of fatty acid; and (3) adding an acid to the mother liquor of step (2) to obtain the long chain dibasic acid.

A system for the crystallization of a substance to be crystallized which is dissolved in a solvent, comprising a crystallization apparatus which is flowed through by a solution to be concentrated which has the substance to be crystallized dissolved therein, and by a heating steam or a heating liquid, wherein the crystallization apparatus has at least one flow passage conducting the solution to be concentrated, at least one flow passage conducting the heating steam or the heating liquid, and at least one flow passage conducting vaporous solvent, wherein a respective flow passage conducting the solution to be concentrated is at least partly separated from a respective flow passage conducting the heating steam or the heating liquid by a steam-impermeable and liquid-impermeable wall and wherein a respective flow passage conducting the solution to be concentrated is at least partly separated from a respective flow passage conducting the vaporous solvent by a membrane wall permeable to the vaporous solvent, but not to the liquid solvent, wherein the crystallization apparatus is configured such that the solution to be concentrated is boiled in the respective flow passage conducting the solution to be concentrated and vaporous solvent produced during the boiling moves through the membrane wall into the adjacent flow passage conducting the vaporous solvent.