Multiple site purification can be achieved by a small plastic portable voltaic inspissation unit in a box configuration. Each unit may feature an air hopper, a recirculation line, a gas diffuser, a centrifuge, a decanter, and multiple anodic and cathodic voltaic inspissation plates that may direct fluid through a box in a meandering or serpentine fashion. Multiple devices may be present or omitted, and retention times may be varied both by the presence or absence of recirculation and the flow rate accomplished by use of different metal in the plates depending on purification goals. Air may be injected interstitially prior to passage into the box to aid in purification, and ultimately both ease of transport and substantially improved purification percentages may be achieved relative to prior systems.

Multiple site purification can be achieved by a small plastic portable voltaic inspissation unit in a box configuration. Each unit may feature an air hopper, a recirculation line, a gas diffuser, a centrifuge, a decanter, and multiple anodic and cathodic voltaic inspissation plates that may direct fluid through a box in a meandering or serpentine fashion. Multiple devices may be present or omitted, and retention times may be varied both by the presence or absence of recirculation and the flow rate accomplished by use of different metal in the plates depending on purification goals. Air may be injected interstitially prior to passage into the box to aid in purification, and ultimately both ease of transport and substantially improved purification percentages may be achieved relative to prior systems.

Provided are devices that include a polymeric separation medium configured to immobilize one or more constituents of interest in the polymeric separation medium and have an increased pore size upon application of an applied stimulus. Systems including the devices, as well as methods of using the devices, are also provided. Embodiments of the present disclosure find use in a variety of different applications, including detecting whether an analyte is present in a fluid sample.

A system for sterilizing a fluid includes a sterilization container bounding a fluid flow path that can be coupled with a fluid source. The sterilization container is comprised of one or more polymeric walls. A beam generator is configured to direct a beam of electromagnetic radiation through at least a portion of the fluid flow path of the sterilization container, the beam of electromagnetic radiation being sufficient to sterilize a fluid within the fluid flow path.

Acoustic perfusion devices for separating biological cells from other material in a fluid mixture are disclosed. The devices include an inlet port, an outlet port, and a collection port that are connected to an acoustic chamber. An ultrasonic transducer creates an acoustic standing wave in the acoustic chamber that permits a continuous flow of fluid to be recovered through the collection port while keeping the biological cells within the acoustic chamber to be returned to the bioreactor from which the fluid mixture is being drawn.

Acoustic perfusion devices for separating biological cells from other material in a fluid mixture are disclosed. The devices include an inlet port, an outlet port, and a collection port that are connected to an acoustic chamber. An ultrasonic transducer creates an acoustic standing wave in the acoustic chamber that permits a continuous flow of fluid to be recovered through the collection port while keeping the biological cells within the acoustic chamber to be returned to the bioreactor from which the fluid mixture is being drawn.

A power supply system for an AC type of coalescerincluding a first transformer, a controllable transformer, a resonant control circuit and a control system. The first transformer has a primary winding with first and second primary terminals and a secondary winding with first and second secondary terminals, where the first and second secondary terminals are provided for connection to electrodes of the coalescer. The controllable transformer has a primary side for connection to an AC power source and a secondary side connected to first and second nodes, where the second node is connected to a second primary terminal of the first transformer. The resonant control circuit is connected between the first node and the second node. The control system is controlling the controllable transformer. The power supply system further comprises a capacitor connected between the first node and a first primary terminal of the first transformer.

A power supply system for an AC type of coalescerincluding a first transformer, a controllable transformer, a resonant control circuit and a control system. The first transformer has a primary winding with first and second primary terminals and a secondary winding with first and second secondary terminals, where the first and second secondary terminals are provided for connection to electrodes of the coalescer. The controllable transformer has a primary side for connection to an AC power source and a secondary side connected to first and second nodes, where the second node is connected to a second primary terminal of the first transformer. The resonant control circuit is connected between the first node and the second node. The control system is controlling the controllable transformer. The power supply system further comprises a capacitor connected between the first node and a first primary terminal of the first transformer.

A device for extracting and concentrating a target analyte including a sample channel that receives the sample, a separation channel, a waste channel, a first junction between the sample channel and the separation channel, and, a second junction between the separation channel and the waste channel. The first junction selectively transports a first group of analytes, including target analytes, from the sample channel to the separation channel in accordance with a size of a first free transport region of the first junction. The second junction selectively transports a second group of analytes from the separation channel to the waste channel in accordance with a size of a second free transport region of the second junction, the second group being a subset of the first group, so as to concentrate a number of the target analytes in the separation channel.

A device for extracting and concentrating a target analyte including a sample channel that receives the sample, a separation channel, a waste channel, a first junction between the sample channel and the separation channel, and, a second junction between the separation channel and the waste channel. The first junction selectively transports a first group of analytes, including target analytes, from the sample channel to the separation channel in accordance with a size of a first free transport region of the first junction. The second junction selectively transports a second group of analytes from the separation channel to the waste channel in accordance with a size of a second free transport region of the second junction, the second group being a subset of the first group, so as to concentrate a number of the target analytes in the separation channel.