A filter unit for a mixing apparatus includes a hydrophilic filter and a hydrophobic vent filter. The hydrophilic filter is configured to receive a fluid including a liquid and gas. The hydrophilic filter is further configured to sterilize the liquid. The hydrophobic vent filter is configured to receive the gas from the hydrophilic filter. The hydrophobic vent filter further includes a vent and a membrane configured to separate an interior of the filter unit from an exterior of the filter unit, the gas being vented from the filter unit by flowing across the membrane and out of the vent. In some embodiments, the filter unit further includes a defoaming device configured to receive gas, foam comprised the liquid containing trapped gas, and some of the liquid from the hydrophilic filter and is further configured to release at least some of the gas from the foam.

A fiber de-gassing membrane includes a plurality of membrane fibers. At least one of the membrane fibers has a first stiffness. The membrane includes reinforcing fibers. The reinforcing fibers are positioned adjacent to at least one of the membrane fibers. The reinforcing fibers have a second stiffness. The second stiffness is greater than the first stiffness.

An oxygenator (10) has a hollow fiber module (19), a cylindrical outer tube (22) that accommodates the hollow fiber module (19), and a sealing structure (82a, 82b) that seals a gap between an outer peripheral portion of the hollow fiber module (19) and an inner peripheral portion of the outer tube (22). The sealing structure (82a, 82b) includes an anchor structure (84a, 84b) that is formed on the outer tube (22) on an inner peripheral side near the end defining a groove recessed in an axial direction of the outer tube (22), a cutout portion (88) formed by cutting out the anchor structure (84a, 84b) on the inner peripheral side, and a sealing material (86a, 86b) with which the anchor structure (84a, 84b) and the gap are filled.

A hollow-fiber membrane according to an aspect of the present disclosure contains a polytetrafluoroethylene or a modified polytetrafluoroethylene as a main component and has an average outer diameter of 1 mm or less and an average inner diameter of 0.5 mm or less. In a measurement of a heat of fusion of the polytetrafluoroethylene or the modified polytetrafluoroethylene with a differential scanning calorimeter, when the polytetrafluoroethylene or modified polytetrafluoroethylene is subjected to a first step of heating from room temperature to 365° C., a second step of cooling from 365° C. to 350° C., maintaining the temperature, subsequently cooling from 350° C. to 330° C., and further cooling from 330° C. to 305° C., and a third step of cooling from 305° C. to 245° C. at a rate of −50° C./min and subsequently heating from 245° C. to 365° C. at a rate of 10° C./min, a heat of fusion from 296° C. to 343° C. in the third step is 30.0 J/g or more and 45.0 J/g or less.

Disclosed is a method of improving the effectiveness of an oxygen removal unit for a fuel supply system. The method includes contacting a tube bundle with a repair liquid at 20 to 40° C. for less than two hours. The tube bundle includes tubes having an air permeable, non-porous polymer layer with discontinuities. The repair liquid includes a solvent and a curable thermoset material. The curable thermoset material is deposited in the discontinuities of the air permeable, non-porous polymer layer and cured. Also disclosed is a fuel system oxygen removal unit including a tubular bundle formed of tubes having an air permeable, non-porous polymer layer disposed on a microporous support wherein the air permeable, non-porous polymer layer includes discrete segments of a cured thermoset material.

Systems, devices, and methods are provided for removing carbon dioxide from a target fluid, such as, for example, blood, to treat hypercarbic respiratory failure or another condition. A device is provided including first and second membrane components for removing dissolved gaseous carbon dioxide and bicarbonate from the fluid, which can be done simultaneously. The device can be in the form of a cartridge configured for use in a dialysis system. A method of treatment is also provided, involving drawing blood from a patient and bringing the patient's blood in contact with a first membrane component having a sweep gas passing therethrough, and a second membrane component having a dialysate passing therethrough. The dialysate's composition can be selected such that charge neutrality is maintained.

A refrigeration system includes a vapor compression loop and a purge system in communication with the vapor compression loop. The purge system includes a separator including for separating contaminants from a purge gas provided from the vapor compression loop to the separator and a movement mechanism operable to increase a pressure of the purge gas. The pressure of the purge gas drives the purge gas through the separator.

The present invention is related to the field of microfluidics and compound distribution within microfluidic devices and their associated systems. In one embodiment, present invention aims to solve the problem of molecule and compound absorbency into the materials making up laboratory equipment, microfluidic devices and their related infrastructure, without unduly restricting gas transport within microfluidic devices.

A system and methodology for the preservation of red blood cells is described in which red blood cells are oxygen or oxygen and carbon dioxide depleted, treated and are stored in an anaerobic environment to optimize preparation for transfusion. More particularly, a system and method for extended storage of red blood cells from collection to transfusion that optimizes red blood cells prior to transfusion is described.

The present invention discloses a rectangular shaped filter and coalescer elements and a vessel that houses a plurality of such rectangular shaped elements. Greater filtration or separation efficiency is provided due to increased number and alignment of rectangular shaped filter elements in the vessel. The rectangular shaped filter elements are also easy to replace.