B01D21/0084

Method and system for buoyant-particle-assisted cell therapy

A system for buoyant-particle-assisted cell therapy includes and/or interfaces with a set of buoyant particles. Additionally or alternatively, the system can include and/or interface with a processing container, a set of processing materials (e.g., buffers, factors, solutions, etc.), and/or any other components. A method for buoyant-particle-assisted cell therapy includes processing the set of cells of interest. Additionally or alternatively, the method can include any or all of: preparing a set of buoyant particles; receiving a sample; and isolating a set of cells of interest from the sample.

METHOD AND SYSTEM FOR BUOYANT SEPARATION

A method and system for buoyant separation of a target constituent of a sample, the method comprising: at a process chamber, combining a volume of substrates having a first density with the sample, thereby producing a population of target-bound complexes comprising the target constituent bound to at least a portion of the volume of substrates; within the process chamber, physically separating the population of target-bound complexes from the sample based upon interaction between the volume of substrates and an applied force; aggregating the population of target-bound complexes at a collection region of the process chamber; extracting the population of target-bound complexes from the process chamber; and processing the target constituent from the population of target-bound complexes for further analysis.

Purified silicon, devices and systems for producing same
09802827 · 2017-10-31 · ·

The present disclosure provides devices and systems that utilize concurrent and countercurrent exchange platforms to produce purified silicon.

Purified silicon, devices and systems for producing same
09783426 · 2017-10-10 · ·

The present disclosure provides devices and systems that utilize concurrent and countercurrent exchange platforms to produce purified silicon.

Solids removal system and method

The system and method is directed to improved separation or clarification of solids from a solids-laden liquid, including the removal of low gravity solids. A liquid to be treated is introduced into the inlet of a solid-liquid separator modified to include one or more sources of vibrational energy. The liquid is directed through a conduit within the separator. This conduit can be configured into a tortuous flow path to assist in the separation of solids from the liquid, the tortuous path being interconnected between two separation towers. Vibrational energy and gas sparging is applied to the flow path. As solids fall out of solution, they are collected. The clarified liquid is also collected. A vacuum can be applied to the system to assist in moving the solid-liquid mixture through the system and to provide vacuum clarification. Electrocoagulation electrodes can also be employed.

SYSTEM AND METHOD FOR TREATING LIQUIDS AND SOLUTIONS TO REMOVE AND/OR SEPARATE COMPONENTS THEREOF USING STABILIZED GAS INFUSED LIQUIDS
20170209814 · 2017-07-27 ·

A system for treating liquids and solutions for separating components thereof, the system including a treatment vessel having a treatment chamber therein, a device for generating a gas-infused liquid under elevated pressure, and a device for stabilizing the gas-infused liquid such that most of the gas infused into the liquid by the device for generating a gas-infused liquid will remain in the liquid if pressure of the liquid is reduced to atmospheric pressure, and for flowing the stabilized gas-infused liquid into the treatment chamber so as to form a liquid layer including the stabilized, gas-infused liquid in the treatment chamber. The treatment vessel includes a discharge port through which some of the stabilized, gas-infused liquid in the liquid layer may be discharged from the treatment vessel, the withdrawn liquid is infused with an additional amount of the gas, again stabilized, and again flown the liquid into the treatment chamber.

Density phase separation device

A mechanical separator for separating a fluid sample into first and second phases is disclosed. The mechanical separator includes a float having a first portion and a second portion, a ballast circumferentially disposed about a section of the float, and a deformable bellows defining an open passageway extending between a first end and a second end. The ballast is longitudinally moveable with respect to the float and engaged with the deformable bellows between the first end and the second end. At least a portion of the float is transitionable from a restraint position to a sealed position through the first end of the bellows. The first portion of the float can be positioned within the interior of the deformable bellows in the restraint position, and the first portion of the float can be positioned at an exterior location longitudinally displaced from the deformable bellows in the sealed position.

Purified Silicon, Devices and Systems for Producing Same
20170197840 · 2017-07-13 ·

The present disclosure provides devices and systems that utilize concurrent and countercurrent exchange platforms to produce purified silicon.

Purified Silicon, Devices and Systems for Producing Same
20170197841 · 2017-07-13 ·

The present disclosure provides devices and systems that utilize concurrent and countercurrent exchange platforms to produce purified silicon.

Acoustic manipulation of particles in standing wave fields

A method for separating a second fluid or a particulate from a host fluid is disclosed. The method includes flowing the mixture through an acoustophoretic device comprising an acoustic chamber, an ultrasonic transducer, and a reflector. The transducer includes a piezoelectric material driven by a voltage signal to create a multi-dimensional acoustic standing wave in the acoustic chamber. A voltage signal is sent to drive the ultrasonic transducer in a displacement profile that is a superposition of a combination of different mode shapes that are the same order of magnitude to create the multi-dimensional acoustic standing wave in the acoustic chamber such that the second fluid or particulate is continuously trapped in the standing wave, and then agglomerates, aggregates, clumps, or coalesces together, and subsequently rises or settles out of the host fluid due to buoyancy or gravity forces, and exits the acoustic chamber.