An in-line fitment for connection of a filter to a pipe includes first and second fluid-carrying portions and a non-fluid-carrying spacer. Each fluid-carrying portion includes a socket for receiving an open end of a pipe and a connector for connection of the filter. A screw compression fitting is provided on each of the sockets of the first and second fluid-carrying portions for forming a sealed connection with the open ends of the pipe. The socket of the first fluid-carrying portion has a pipe receiving depth greater than that of the socket of the second fluid-carrying portion for enabling movement of the fitment parallel to the pipe when engaged with one of the open ends of the pipe. The sockets of the first and second fluid-carrying portions are positioned on a common axis and facing away from each other when the fluid-carrying portions are linked by the spacer.

An in-line fitment for connection of a filter to a pipe includes first and second fluid-carrying portions and a non-fluid-carrying spacer. Each fluid-carrying portion includes a socket for receiving an open end of a pipe and a connector for connection of the filter. A screw compression fitting is provided on each of the sockets of the first and second fluid-carrying portions for forming a sealed connection with the open ends of the pipe. The socket of the first fluid-carrying portion has a pipe receiving depth greater than that of the socket of the second fluid-carrying portion for enabling movement of the fitment parallel to the pipe when engaged with one of the open ends of the pipe. The sockets of the first and second fluid-carrying portions are positioned on a common axis and facing away from each other when the fluid-carrying portions are linked by the spacer.

A system and associated method for concentrating and separating components of different densities from fluid containing cells using a centrifuge includes a syringe and a syringe holder, the syringe having a proximal top with a luer port, a sidewall extending from the top forming a syringe tube, and a plunger slidably disposed inside the syringe tube, the plunger forming a sealing engagement with the sidewall, the syringe holder defining a cavity for receiving the syringe, wherein a distal end of the syringe tube is at least partially closed by the syringe holder after the plunger is placed inside the syringe tube. The method includes receiving a fluid containing cells in the syringe; placing the syringe and syringe holder into a centrifuge; exposing the syringe and syringe holder to elevated g force in the centrifuge, the syringe holder being in physical contact with the sidewall on the distal end to provide support and prevent fluid from leaking outside the syringe; removing the syringe from the centrifuge; and extracting separated layers containing cells using the luer port of the syringe as an access port.

A system and method of isolating extracellular vesicles. The method includes loading one or more of blood or bone marrow into an input port of a concentration system and centrifuging one or more of the blood or bone marrow to separate one or more of red blood cells, platelet poor plasma, or platelet rich plasma/bone marrow concentrate fractions via a centrifuge device. The method further includes pumping one or more of bone marrow/platelet rich plasma fractions and platelet poor plasma fractions into a receptacle of the concentration system and adding a concentrated aqueous two-phase solution to one or more of the bone marrow concentrate/platelet rich plasma fractions and platelet poor plasma fractions. The method also includes drawing the concentrated aqueous two-phase solution and one or more of the bone marrow concentrate/platelet rich plasma fractions or platelet poor plasma fractions back into the centrifuge device to isolate one or more of extracellular vesicles and platelet rich plasma/bone marrow concentrate fractions.

A centrifugal piston according to an embodiment comprises: a piston body defining a path which extends from the front of the piston to the rear of the piston, and through which substances at the front of the piston can move to the rear of the piston; and a valve disposed on the path and configured to selectively open or block the path, wherein, during centrifugation in which centrifugal force acts on the piston, the substances at the front of the piston are centrifuged while the valve is blocking the path, and, when an external force is applied to the piston while the centrifugal force does not act on the piston, the valve moves freely relative to the piston body, and when the valve opens the path, at least a portion of the substances at the front of the piston can move to the rear of the piston.

A centrifugal device includes a container having a body with a first end and a second end disposed opposite to the first end. A cap is coupled to the second end of the container, and the cap includes a top surface having at least one port configured to receive or transmit one or more of air or fluid. So configured, the container is moveable between an upright position, in which a first fluid disposed in the container is centrifuged to precipitate at least one extracellular vesicle separate from the first fluid, and an inverted position in which one or more of the first fluid having at least one extracellular vesicle depleted therefrom is removed from the container and a second fluid mixed with the at least one extracellular vesicle removed is withdrawn from the container for injection.

A drilling mud treatment unit (100) comprises a primary duct (10) for feeding coagulated drilling mud, an in-line flocculation system (20) for flocculating the coagulated drilling mud flowing in the primary duct (10), and at least one hydrocyclone (30) fed by the primary duct (10) and arranged downstream from the flocculation system (20). The hydrocyclone (30) has an overflow orifice (32) for receiving a liquid product resulting from treatment of the drilling mud and an underflow orifice (34) for receiving a solid product resulting from treatment of the drilling mud. The overflow orifice (32) presents an overflow diameter (Do) and the underflow orifice presents an underflow diameter (Du), and the underflow diameter (Du) is greater than 1.1 times the overflow diameter (Do).

A dewatering screen includes a frame upon which is mounted a deck having a plurality of apertures therein, the frame being mounted on a base and being provided with vibration generator for imparting vibration to the deck. A delivery means delivers wet particulate material to be dewatered onto the deck, and there is at least one dividing wall extending across a portion of the deck, the dividing wall(s) separating the deck into a material dewatering region and one or more water drainage regions. The delivery means delivers wet particulate material to be dewatered onto the material dewatering region.

Disclosed herein a Cyclone Filter for separating heavy particles from water or any other liquid. The filter comprises a Head (1) to introduce the liquid into the Filter, causing the liquid to swirl enhanced by internal shape of head (1) and flow of liquid takes turn around vertex pipe (3), said liquid containing solid foreign matter; a vertical Vertex pipe (3) to lead clean water out of the filter; a Vane (2) to separate Head from separation chamber; a Hollow Cylindrical separation chamber (4) where particles of more mass will be pushed away from the central axis and towards the wall due to increased flowrate and swirling action; a collection tank (6) to collect the dropped particles; characterized in that the vane (2) comprises curved surfaces with substantially elliptical pathways (2A) perpendicular the Vertex pipe (3) that enhances the velocity of flow and its swirling action.

A separator, for separating solids from a liquid, comprises a hydrodynamic separator, a first filtration device, a first backwash device, a second filtration device, and a second backwash device. The first filtration device comprises a first inlet at a first level for receiving at least a first portion of the liquid from the hydrodynamic separator, and a first filter for filtering the first portion of the liquid received via the first inlet. During filtration of the first portion of the liquid, the first portion of the liquid passes through the first filter away from the first inlet and a first portion of solids is retained by the first filter. The first filter is located between the first inlet and the first backwash device. The first backwash device is configured to alternately prevent and allow the passage of the first portion of the liquid through the first backwash device such that, when the passage of the first portion of the liquid through the first backwash device is prevented, the first portion of the liquid that has passed through the first filter passes back through the first filter toward the first inlet so as to remove the first portion of solids from the first filter. The second filtration device comprises a second inlet at a second level higher than the first level for receiving a second portion of the liquid from the hydrodynamic separator, and a second filter for filtering the second portion of the liquid received via the second inlet. During filtration of the second portion of the liquid, the second portion of the liquid passes through the second filter away from the second inlet, and a second portion of solids is retained by the second filter. The second filter is located between the second inlet and the second backwash device. The second backwash device is configured to alternately prevent and allow the passage of the second portion of the liquid through the second backwash device such that, when the passage of the second portion of the liquid through the second backwash device is prevented, the second portion of the liquid that has passed through the second filter passes back through the second filter toward the second inlet so as to remove the second portion of solids from the second filter.