The present invention relates to a tubular oil separator providing separation of respective fluid components mixed in fluids from oil wells, wherein the tubular oil separator A is arranged to mitigate problems related to turbulence and possible non-Newtonian fluid behaviors of fluid components mixed in the fluids from the oil wells in the oil separator. The invention further relates to a method of operating a separator. Moreover the invention relates to a system of multiple separators. Inventive aspects of the separator comprises an elongated outer, closed tubular section and an elongated, inner tubular section, which is closed in one end and open in another end, —where the inner tubular section is arranged inside the outer tubular section, —and where oil well substances are introduced into the open end of the inner tubular section via a tube feed section passing through the outer tubular section and into the inner tubular section, —and where the inner tubular section comprises multiple, elongated and parallel slots arranged in a longitudinal direction of the inner tubular section in a circumferential manner, —where the inclination of the separator facilitates separation of the oil well substances into lower density substances and higher density substances, —where the lower density substances by buoyancy drift upward through the slots and exit via an upper outlet in the outer tubular section and higher density substances sink downward through the slots and by gravitation exit via a lower outlet in the outer tubular section.

An acoustic standing wave is utilized to separate components from a multi-component fluid, such as animal cells from fluid-cell mixture, in a fluid flow scheme with an acoustophoresis device. For example, the flow scheme and device allows for trapping of falling cells as the cells coalesce, agglomerate, and the weight of the agglomerated mass overcomes the drag and ultrasonic standing wave forces in the device.

An acoustophoresis device includes an acoustic chamber with a piezoelectric element located within its volume. The piezoelectric element vibrates and generates acoustic standing waves from both sides, so that particles can be separated from fluid passing through the acoustic chamber. This permits the element to be cooled more efficiently, reducing transient heat loads in the fluid traveling through the device.

Separation of particles or droplets from a host fluid may be achieved using a transducer and/or reflector that is a thin, non-planar structure. The thin non-planar structure improves operation of an acoustic standing wave generated by an acoustic transducer. The structure may operate as a pressure release boundary and may be constructed as plastic film.

Acoustophoretic devices and methods for separating biological cells (particularly T-cells) from other fluids/materials using multi-dimensional acoustic standing waves are disclosed. The devices include an inlet, at least two outlets, and a flow chamber having an ultrasonic transducer-reflector pair. Specifically, T cells, B cells, or NK cells can be separated from other blood components. A dual-pass acoustophoretic system including two acoustophoretic devices arranged in series and fluidly connected to one another is also illustrated. Means for pre-chilling the mixture prior to separation in the devices or system can be used to improve retention, concentration, and clarification and to prevent outgassing.

A system for enhancing the separation of particles or fluids from water is disclosed. A settling tank or skim tank is provided with an open submersible acoustophoretic separator. In a skim tank, the separator captures and holds oil droplets or particles, permitting them to coalesce until they are large enough and have sufficient buoyant force to float to the top of the tank. In a settling or sediment tank, separator captures and holds particles until they are large enough that the force of gravity causes them to settle out of the water. The acoustophoretic device thus speeds up separation of the particles or droplets from the water.

A method and system are provided for extracting a target analyte from a sample using acoustic ejection technology. The method involves applying focused acoustic energy to a fluid reservoir housing a fluid composition that contains a target analyte and comprises an upper region and a lower region, where the concentration of the target analyte in the upper region differs from that in the lower region. The focused acoustic energy is applied in a manner that is effective to result in the ejection of a fluid droplet from the fluid composition into a droplet receiver, wherein the concentration of the analyte in the droplet corresponds to either the concentration of the analyte in the upper region or the concentration of the analyte in the lower region, and wherein the concentration of the analyte is substantially uniform throughout the droplet. The fluid composition may comprise an ionic liquid, used in the extraction of ionic target analytes. Related methods and an acoustic extraction system are also provided.

Acoustophoretic devices for separating particles from a non-flowing host fluid are disclosed. The devices include a substantially acoustically transparent container and a separation unit, with the container being placed within the separation unit. An ultrasonic transducer in the separation unit creates a planar or multi-dimensional acoustic standing wave within the container, trapping particles disposed within the non-flowing fluid and causing them to coalesce or agglomerate, then separate due to buoyancy or gravity forces.

Devices, systems, and methods for separating cells or vesicles using a thermo-acoustophoretic approach are provided. A microfluidic device can be used for stiffness-based separation of cells or vesicles that otherwise have the same or approximately the same size, shape, and charge, where at least some of the membranes or vesicles have different compositions. The separation can be done by tuning the temperature of the cells or vesicles.

Apparatus is provided featuring an acoustic driver and a transducer. The acoustic driver is configured to provide an acoustic driver signal having a frequency that can be adjusted to yield a given wavelength, which in turn, will selectively capture a particular particle size of particles in a fluid, mixture or process flow. The transducer is configured to respond to the acoustic driver signal and provide an acoustic signal having a standing wave at the frequency in order to yield the given wavelength that will selectively capture the particular particle size of the particles in the fluid, mixture or process flow, in order to determine the mass of the particles having the particular particle size in the fluid, mixture or process flow.