A horizontal pressure filter including a washing liquid recovery channel for receiving unused washing liquid from the washing liquid inlet channel and conducting said unused washing liquid to a washing liquid recovery outlet. A flow controller arranged to selectively open and close a flow connection between the washing liquid inlet channel and the washing liquid recovery channel, and respectively, between a compressed gas inlet and the washing liquid inlet channel, such that a gas flow from the compressed gas inlet to the washing liquid recovery channel via the washing liquid inlet channel may be induced, so as to flush unused washing liquid remaining in the washing liquid inlet channel to the washing liquid recovery outlet.

The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methodsincluding high throughput methodsfor screening cells that have been subjected to editing and identifying cells that have been properly edited.

A filter press (100) is described comprising: a plurality of filtration chambers (155) each of which is delimited by two mutually facing filtering septa (140, 145) interposed between a pair of containment plates (105), a movement apparatus adapted to move each pair of containment plates (105) between a closed configuration and an open configuration, an inlet hydraulic circuit of the liquid to be filtered, an outlet hydraulic circuit of the filtered liquid, and a washing robot (400) adapted to wash the filtering septa (140, 145) that delimit each filtration chamber (155), wherein said washing robot (400) comprises: a trolley (405) adapted to move along a longitudinal direction (A) with respect to the containment plates (105), a bar (445) installed on the trolley (405) and movable relative thereto in a transverse direction with respect to the longitudinal direction (A), and a plurality of nozzles (450) installed on said bar (445) to dispense jets of a washing liquid toward said filtering septa (140, 145), the filter press further comprising: a plurality of identification codes, each of which is fixed to at least one respective filtering septum (140, 145), a device for detecting said identification codes installed on the trolley (405) of the washing robot (400), at least one image acquisition device (600) installed on the bar (445) of the washing robot (400) to acquire images of said filtering septa (140, 145), and an electronic processing unit connected to the identification code detection device and to the image acquisition device (600).

A horizontal pressure filter including a washing liquid recovery channel for receiving unused washing liquid from the washing liquid inlet channel and conducting said unused washing liquid to a washing liquid recovery outlet. A flow controller arranged to selectively open and close a flow connection between the washing liquid inlet channel and the washing liquid recovery channel, and respectively, between a compressed gas inlet and the washing liquid inlet channel, such that a gas flow from the compressed gas inlet to the washing liquid recovery channel via the washing liquid inlet channel may be induced, so as to flush unused washing liquid remaining in the washing liquid inlet channel to the washing liquid recovery outlet.

A fluid filter system has at least one filter having a filter head removable filter element, the filter being oriented inverted. A first filter drain check valve is provided with its inlet in fluid communication with the inlet of the at least one filter, and a second filter drain check valve is provided with its inlet in fluid communication with the outlet of the at least one filter. A filter outlet check valve is provided with its inlet in fluid communication with the outlet of at least one filter head. An openable valve is provided in fluid communication with the outlets of the first and second filter drain check valves. A drain pump is provided with its intake in fluid communication with the valve. A drain pump check valve is included with its inlet in fluid communication with the output of the drain pump and an outlet in fluid communication with the outlet of the filter outlet check valve.

The present invention relates to a filter device for capturing a target cell and a target cell collecting method using the same. A filter substrate by which a target cell is captured is formed of an elastic material. When blood passes, the size of a lattice hole of the filter substrate by which the target cell is captured is reduced. When the blood completely passes, the size of the lattice hole of the filter substrate by which the target cell is captured is restored, so that a destruction rate of the target cell may be reduced and a collect rate of the target cell may be increased.

A fluid filter system has at least one filter having a filter head removable filter element, the filter being oriented inverted. A first filter drain check valve is provided with its inlet in fluid communication with the inlet of the at least one filter, and a second filter drain check valve is provided with its inlet in fluid communication with the outlet of the at least one filter. A filter outlet check valve is provided with its inlet in fluid communication with the outlet of at least one filter head. An openable valve is provided in fluid communication with the outlets of the first and second filter drain check valves. A drain pump is provided with its intake in fluid communication with the valve. A drain pump check valve is included with its inlet in fluid communication with the output of the drain pump and an outlet in fluid communication with the outlet of the filter outlet check valve.

A filter press (100) is described comprising: a plurality of filtration chambers (155) each of which is delimited by two mutually facing filtering septa (140, 145) interposed between a pair of containment plates (105), a movement apparatus adapted to move each pair of containment plates (105) between a closed configuration and an open configuration, an inlet hydraulic circuit of the liquid to be filtered, an outlet hydraulic circuit of the filtered liquid, and a washing robot (400) adapted to wash the filtering septa (140, 145) that delimit each filtration chamber (155), wherein said washing robot (400) comprises: a trolley (405) adapted to move along a longitudinal direction (A) with respect to the containment plates (105), a bar (445) installed on the trolley (405) and movable relative thereto in a transverse direction with respect to the longitudinal direction (A), and a plurality of nozzles (450) installed on said bar (445) to dispense jets of a washing liquid toward said filtering septa (140, 145), the filter press further comprising: a plurality of identification codes, each of which is fixed to at least one respective filtering septum (140, 145), a device for detecting said identification codes installed on the trolley (405) of the washing robot (400), at least one image acquisition device (600) installed on the bar (445) of the washing robot (400) to acquire images of said filtering septa (140, 145), and an electronic processing unit connected to the identification code detection device and to the image acquisition device (600).