Provided herein are, inter alia, biological manufacturing and downstream purification processes.

Provided herein are, inter alia, biological manufacturing and downstream purification processes.

Provided herein are, inter alia, biological manufacturing and downstream purification processes.

Provided herein are, inter alia, biological manufacturing and downstream purification processes.

Provided herein are, inter alia, biological manufacturing and downstream purification processes.

Provided herein are, inter alia, biological manufacturing and downstream purification processes.

Water-based compositions suitable for the hydration of a mammal, and particularly hydration of a human by oral or topical methods, and for industrial uses such as cooling, and the making of solutions and mixtures. A method for producing a beverage, an industrial process water, an industrial solvent, or topical dermatological composition includes: providing a water source, the water molecules having oxygen or hydrogen atoms of different isotopes, (i) fractionating the water source to produce a fraction enriched in water molecules having an abundance of at least one of the oxygen or hydrogen isotopes being greater or less than the abundance found in the water source, or (ii) where the water source is already enriched in heavy water, fully or partially maintaining the level of enrichment.

An isotope separation method, including introducing a first reactant stream (109), containing a natural abundance of at least one desired isotopologue molecule, a second reactant stream (110), and a recycle stream (112) into a photochemical reactor (101), thus producing a raw product stream (115), introducing the raw product stream (115) into a separation device (116), thus producing at least a product stream (117), a gas filter stream (113), and the recycle stream (112), and introducing at least a portion of the gas filter stream (113) into an unconventional (gas) filter (103), wherein the product stream (117) includes the at least one desired isotopologue molecule.

A method for producing a magnetic material includes: selecting a mixture of isotopes of a chemical element having a desired magnetic characteristic; identifying an isotope in the mixture of isotopes meeting a selection criterion; removing the identified isotope from the mixture of isotopes using an isotope separation device to produce an enriched mixture of isotopes having a decreased concentration of the identified isotope; wherein the enriched mixture of isotopes is the magnetic material.

A method for producing a magnetic material includes: selecting a mixture of isotopes of a chemical element having a desired magnetic characteristic; identifying an isotope in the mixture of isotopes meeting a selection criterion; removing the identified isotope from the mixture of isotopes using an isotope separation device to produce an enriched mixture of isotopes having a decreased concentration of the identified isotope; wherein the enriched mixture of isotopes is the magnetic material.