According to various aspects and embodiments, a system and method for polishing ultrapure water (UPW) is disclosed. The water polishing system includes a source of ultrapure water (UPW), an ultrafiltration (UF) module having an inlet and a permeate outlet, a recirculation conduit communicating the permeate outlet with the inlet and forming a recirculation loop, a recirculation pump disposed along the recirculation conduit upstream from the inlet of the UF module and fluidly coupled to the source of UPW, a supply conduit fluidly coupled to the recirculating conduit and a demand source, the supply conduit positioned downstream from the permeate outlet, and a pressure control valve disposed along the recirculation conduit downstream from the supply conduit and configured to maintain pressure of permeate at a predetermined value.

According to various aspects and embodiments, a system and method for polishing ultrapure water (UPW) is disclosed. The water polishing system includes a source of ultrapure water (UPW), an ultrafiltration (UF) module having an inlet and a permeate outlet, a recirculation conduit communicating the permeate outlet with the inlet and forming a recirculation loop, a recirculation pump disposed along the recirculation conduit upstream from the inlet of the UF module and fluidly coupled to the source of UPW, a supply conduit fluidly coupled to the recirculating conduit and a demand source, the supply conduit positioned downstream from the permeate outlet, and a pressure control valve disposed along the recirculation conduit downstream from the supply conduit and configured to maintain pressure of permeate at a predetermined value.

An external circulation-type hollow fiber membrane module which has a high processing capacity and which is capable of inhibiting a to-be-treated liquid within a case from flowing through a short path and efficiently bringing the liquid into contact with a hollow fiber membrane in whichever direction of a vertical direction, a horizontal direction, etc., the liquid flows. An external circulation-type hollow fiber membrane module is provided with: a hollow fiber membrane bundle; a case; and a short-path prevention body that blocks flowing of a to-be-treated liquid in a gap between the hollow fiber membrane bundle and the case, wherein a first end of the hollow fiber membrane bundle is fixed in the case, and the short-path prevention body is provided to the downstream side of a first port which is a liquid flow-in port in the case so as to project from the inner surface of the case.

An external circulation-type hollow fiber membrane module which has a high processing capacity and which is capable of inhibiting a to-be-treated liquid within a case from flowing through a short path and efficiently bringing the liquid into contact with a hollow fiber membrane in whichever direction of a vertical direction, a horizontal direction, etc., the liquid flows. An external circulation-type hollow fiber membrane module is provided with: a hollow fiber membrane bundle; a case; and a short-path prevention body that blocks flowing of a to-be-treated liquid in a gap between the hollow fiber membrane bundle and the case, wherein a first end of the hollow fiber membrane bundle is fixed in the case, and the short-path prevention body is provided to the downstream side of a first port which is a liquid flow-in port in the case so as to project from the inner surface of the case.

In one aspect, a system includes a blood treatment machine; a dialyzer configured to be coupled to the blood treatment machine, the dialyzer including a dialyzer housing defining a blood inlet and a blood outlet; a bundle of hollow fibers within an interior of the dialyzer housing; a pumping device drivable to force blood received from the blood inlet through lumens of the bundle of hollow fibers and out the blood outlet; a dialysate inlet port in fluid communication with a dialysate flow path that includes space in the interior of the dialyzer housing between the bundle of hollow fibers; and a dialysate outlet port in fluid communication with the dialysate flow path. The system further includes a fluid conditioning system configured to (i) prepare and supply fresh dialysate to the dialyzer via the dialysate inlet port, and (ii) receive spent dialysate from the dialyzer via the dialysate outlet port, recycle the spent dialysate, and supply the recycled dialysate to the dialyzer via the dialysate inlet port.

In one aspect, a system includes a blood treatment machine; a dialyzer configured to be coupled to the blood treatment machine, the dialyzer including a dialyzer housing defining a blood inlet and a blood outlet; a bundle of hollow fibers within an interior of the dialyzer housing; a pumping device drivable to force blood received from the blood inlet through lumens of the bundle of hollow fibers and out the blood outlet; a dialysate inlet port in fluid communication with a dialysate flow path that includes space in the interior of the dialyzer housing between the bundle of hollow fibers; and a dialysate outlet port in fluid communication with the dialysate flow path. The system further includes a fluid conditioning system configured to (i) prepare and supply fresh dialysate to the dialyzer via the dialysate inlet port, and (ii) receive spent dialysate from the dialyzer via the dialysate outlet port, recycle the spent dialysate, and supply the recycled dialysate to the dialyzer via the dialysate inlet port.

An extracorporeal blood treatment machine for carrying out a blood treatment including a machine front on which a hollow fiber filter module is arranged in a horizontal position, which hollow fiber filter module includes a cylindrical housing, a blood chamber having a blood inlet nozzle and a blood outlet nozzle and a solution chamber having a solution inlet nozzle extending transversely to the longitudinal direction of the hollow fiber filter module and a solution outlet nozzle extending transversely to the longitudinal direction of the hollow fiber filter module, the solution chamber being semi-permeably communicated at least in portions with the blood chamber, wherein a height potential is present in the horizontal position between the solution inlet nozzle and the solution outlet nozzle so that drainage of solution is enabled via one of the solution nozzles and evacuation of air bubbles is enabled via an other of the solution nozzles.

An extracorporeal blood treatment machine for carrying out a blood treatment including a machine front on which a hollow fiber filter module is arranged in a horizontal position, which hollow fiber filter module includes a cylindrical housing, a blood chamber having a blood inlet nozzle and a blood outlet nozzle and a solution chamber having a solution inlet nozzle extending transversely to the longitudinal direction of the hollow fiber filter module and a solution outlet nozzle extending transversely to the longitudinal direction of the hollow fiber filter module, the solution chamber being semi-permeably communicated at least in portions with the blood chamber, wherein a height potential is present in the horizontal position between the solution inlet nozzle and the solution outlet nozzle so that drainage of solution is enabled via one of the solution nozzles and evacuation of air bubbles is enabled via an other of the solution nozzles.

A process for the efficient transfer of molecules between phases employing mesoporous poly (aryl ether ketone) hollow fiber membranes is provided. The method addresses the controlled transfer of reactants into and removal of reaction products from a reaction media and the removal and separation of target molecules from process streams by membrane-assisted liquid-liquid extraction. A number of possible modes of liquid-liquid extraction are possible according to the invention by utilizing porous poly (aryl ether ketone) hollow fiber membranes of Janus-like structure that exhibit a combination of hydrophilic and hydrophobic surface characteristics. The method of the present invention can address the continuous manufacture of chemicals in membrane reactors and is useful for a broad range of separation applications, including separation and recovery of active pharmaceutical ingredients.

A membrane humidifier for a fuel cell, of the present invention, comprises: a middle case in which a plurality of hollow fiber membranes are accommodated; a cap case coupled to the middle case; potting parts formed at the ends of the plurality of hollow fiber membranes; an assembly member disposed between the cap case and the end of the middle case so as to provide air tight coupling therebetween; and a protrusion part extending toward the edges of the potting parts from the inside of the cap case so as to provide air tight coupling between the cap case and the potting parts.