A management device for a water treatment facility includes: a transmembrane pressure difference prediction unit configured to predict a general trend in a transmembrane pressure difference in a water treatment system based on an operation information, the operation information being related to the water treatment system including a membrane separation device installed therein; a chemical solution cleaning planning unit configured to devise such a chemical solution cleaning plan that chemical solution cleaning is performed before a period when a value of the transmembrane pressure difference predicted reaches a specified value; and a chemical solution order placement information generation unit configured to generate chemical solution order placement information based on the and the cleaning chemical solution stock information.

A management device for a water treatment facility includes: a transmembrane pressure difference prediction unit configured to predict a general trend in a transmembrane pressure difference in a water treatment system based on an operation information, the operation information being related to the water treatment system including a membrane separation device installed therein; a chemical solution cleaning planning unit configured to devise such a chemical solution cleaning plan that chemical solution cleaning is performed before a period when a value of the transmembrane pressure difference predicted reaches a specified value; and a chemical solution order placement information generation unit configured to generate chemical solution order placement information based on the and the cleaning chemical solution stock information.

An ion separator according to an embodiment of the present invention includes: a first electrode buffer channel and a second electrode buffer channel; a main channel that connects between the first electrode buffer channel and the second buffer channel; a first ion exchange membrane positioned between the first electrode buffer channel and the main channel; a porous second ion exchange membrane that is provide across the main channel and contains pores of different sizes; a first electrode electrically connected to the main channel with the first electrode buffer channel in between; and a second electrode electrically connected to the main channel with the second electrode buffer channel in between, wherein the second ion exchange membrane may be inserted into the main channel while being inclined toward a fluid flowing through the main channel.

An assembly includes a housing with opposite first and second layers. The first and second layers are spaced apart to define a confined interior space. A semi-permeable membrane is attached to the first layer, the semi-permeable membrane covering a porous area portion of the first layer. An outlet port and an inlet port are in fluid communication with the interior space. The assembly includes a first circulator for circulating a first fluid between the outlet port and the inlet port, and a second circulator for circulating a second fluid along an exterior surface of the semi-permeable membrane. The second circulator includes a fluid duct attached to or integrated within the housing. The fluid duct is isolated from the interior space and is porous to provide fluid access to an exterior surface of the semi-permeable membrane. The semi-permeable membrane forms a barrier allowing exchange of compounds across the membrane.

An assembly includes a housing with opposite first and second layers. The first and second layers are spaced apart to define a confined interior space. A semi-permeable membrane is attached to the first layer, the semi-permeable membrane covering a porous area portion of the first layer. An outlet port and an inlet port are in fluid communication with the interior space. The assembly includes a first circulator for circulating a first fluid between the outlet port and the inlet port, and a second circulator for circulating a second fluid along an exterior surface of the semi-permeable membrane. The second circulator includes a fluid duct attached to or integrated within the housing. The fluid duct is isolated from the interior space and is porous to provide fluid access to an exterior surface of the semi-permeable membrane. The semi-permeable membrane forms a barrier allowing exchange of compounds across the membrane.

A hollow fibre membrane having a coiled, a hemihelix, a helical or an undulated native form, in which the membrane can be stretched by up to 4-times its original length with no plastic deformation, and wherein the native form of the membrane is produced by the asymmetric flow of liquid polymer through an opening of a die or nozzle.

A hollow fibre membrane having a coiled, a hemihelix, a helical or an undulated native form, in which the membrane can be stretched by up to 4-times its original length with no plastic deformation, and wherein the native form of the membrane is produced by the asymmetric flow of liquid polymer through an opening of a die or nozzle.

A filter medium according to one embodiment of the present invention comprises: a first support having a plurality of pores; a nanofiber web comprising nanofibers disposed on upper and lower portions of the first support and forming a three-dimensional network structure, and a hydrophilic coating layer formed on at least a part of an outer surface of the nanofibers, wherein the hydrophilic coating layer is formed of a hydrophilic coating composition comprising a hydrophilic polymer compound having at least one functional group selected from a hydroxyl group and a carboxyl group and a crosslinking agent comprising at least one sulfone group; and a second support having a plurality of pores interposed between the first support and the nanofiber web.

A filter medium according to one embodiment of the present invention comprises: a first support having a plurality of pores; a nanofiber web comprising nanofibers disposed on upper and lower portions of the first support and forming a three-dimensional network structure, and a hydrophilic coating layer formed on at least a part of an outer surface of the nanofibers, wherein the hydrophilic coating layer is formed of a hydrophilic coating composition comprising a hydrophilic polymer compound having at least one functional group selected from a hydroxyl group and a carboxyl group and a crosslinking agent comprising at least one sulfone group; and a second support having a plurality of pores interposed between the first support and the nanofiber web.

Provided are methods, devices, and kits for the isolation of extracellular vesicles using silicon nanomembranes. A method for EV isolation includes the steps of collecting a biofluid sample, contacting the biofluid sample with a pre-filtration membrane, thereby forming a first filtrate and a first retentate, optionally, washing the first retentate of the pre-filtration membrane, contacting the first filtrate from the pre-filtration membrane with a capture membrane, thereby forming a second filtrate and a second retentate, optionally, washing the second retentate, and eluting the second retentate from the capture membrane or lysing the second retentate to recover the contents.