An apparatus and method for filtering a fluid is provided. The apparatus includes a filtration unit having an inlet and hollow fiber membranes. The hollow fiber membranes are each formed from an elongated tube having an exterior surface and an interior surface. The hollow fiber membranes are configured to separate the filtration unit into a permeate side that allows permeate to exit the filtration unit through a permeate outlet and a retentate side that allows retentate to exit the filtration unit through a retentate outlet. The hollow fiber membranes include a coating linked to the exterior surface or interior surface of the hollow fiber membranes. The coating includes a poly electrolyte electrostatically coupled to the charged exterior surface or the charged interior surface.

A method for preparing a durably hydrophilic and uniform-pore ultrafiltration membrane is disclosed herein. Chemical reactions between the functional groups and the active bonds of the molecular chains in the membrane materials are initiated perform the grafting of hydrophilic chains on the polymer chains under conventional dissolution conditions of the polymer membrane material (dissolution with synchronized hydrophilization), so as to realize durable hydrophilization of the membrane materials. The resulting hydrophilized polymer solution (a nascent-state membrane) is introduced into a coagulation bath to initiate a crosslinking reaction among the hydrophilic chains. The resulting crosslinking serves to synergistically regulate subsequent phase separation and membrane formation (phase separation under synergistic crosslinking).

A method for preparing a durably hydrophilic and uniform-pore ultrafiltration membrane is disclosed herein. Chemical reactions between the functional groups and the active bonds of the molecular chains in the membrane materials are initiated perform the grafting of hydrophilic chains on the polymer chains under conventional dissolution conditions of the polymer membrane material (dissolution with synchronized hydrophilization), so as to realize durable hydrophilization of the membrane materials. The resulting hydrophilized polymer solution (a nascent-state membrane) is introduced into a coagulation bath to initiate a crosslinking reaction among the hydrophilic chains. The resulting crosslinking serves to synergistically regulate subsequent phase separation and membrane formation (phase separation under synergistic crosslinking).

A mechanical kidney transplant designed may include a four modules designed to interconnect to clean blood. The first module may include a plurality of pump modules and a resin gel regeneration module, wherein the first module is operatively attached to a patient's iliac artery, iliac vein, and bladder. The second module may be operatively attached to the first module and may include storage and pump systems. The third module may be operatively attached to the first and fourth modules and may include a housing with ports for inflow/outflow of the blood and the physiologic resin gel between the first module and the fourth module. The fourth module may include at least one dialyzer fiber sized to accommodate a volume of blood flowing therethrough and an area surrounding the dialyzer fiber may be sized to accommodate a volume of a physiologic resin gel flowing counter current to the blood.

A process for the efficient transfer of molecules between phases employing mesoporous poly (aryl ether ketone) hollow fiber membranes is provided. The method addresses the controlled transfer of reactants into and removal of reaction products from a reaction media and the removal and separation of target molecules from process streams by membrane-assisted liquid-liquid extraction. A number of possible modes of liquid-liquid extraction are possible according to the invention by utilizing porous poly (aryl ether ketone) hollow fiber membranes of Janus-like structure that exhibit a combination of hydrophilic and hydrophobic surface characteristics. The method of the present invention can address the continuous manufacture of chemicals in membrane reactors and is useful for a broad range of separation applications, including separation and recovery of active pharmaceutical ingredients.

A process for the efficient transfer of molecules between phases employing mesoporous poly (aryl ether ketone) hollow fiber membranes is provided. The method addresses the controlled transfer of reactants into and removal of reaction products from a reaction media and the removal and separation of target molecules from process streams by membrane-assisted liquid-liquid extraction. A number of possible modes of liquid-liquid extraction are possible according to the invention by utilizing porous poly (aryl ether ketone) hollow fiber membranes of Janus-like structure that exhibit a combination of hydrophilic and hydrophobic surface characteristics. The method of the present invention can address the continuous manufacture of chemicals in membrane reactors and is useful for a broad range of separation applications, including separation and recovery of active pharmaceutical ingredients.

The invention relates to the providing of hydrophobic and hydrophilic polymer-based hollow fiber membranes containing a water-insoluble antioxidant; in particular, the invention relates to the providing of hollow fiber membranes for the extracorporeal treatment of blood, wherein the hollow fiber membranes have improved biocompatibility relative to treatment blood, in particular improved complement activation and lower platelet loss vis-à-vis treatment blood. At the same time, the elution of hydrophilic polymers from the lumen of the hollow fiber membrane is reduced.

The invention relates to the providing of hydrophobic and hydrophilic polymer-based hollow fiber membranes containing a water-insoluble antioxidant; in particular, the invention relates to the providing of hollow fiber membranes for the extracorporeal treatment of blood, wherein the hollow fiber membranes have improved biocompatibility relative to treatment blood, in particular improved complement activation and lower platelet loss vis-à-vis treatment blood. At the same time, the elution of hydrophilic polymers from the lumen of the hollow fiber membrane is reduced.

Disclosed is a method for treating wastewater containing heavy metal. First, the wastewater containing heavy metal is subjected to a homogenization treatment, such that the water quality of the wastewater containing heavy metal from different processes is homogenized. The homogenized wastewater containing heavy metal is subjected to an anaerobic-aerobic circulating treatment in a membrane bioreactor (2), in which heavy metal ions are reduced by the action of microorganisms in the anaerobic treatment process. The membrane bioreactor (2) is filled with a hollow fiber membrane (3) containing a quinone group, which serves as an electron mediator that can accelerate the enzymatic reduction of heavy metal ions during the anaerobic treatment. During the aerobic treatment, the COD and SS in the wastewater are further removed.

Disclosed is a method for treating wastewater containing heavy metal. First, the wastewater containing heavy metal is subjected to a homogenization treatment, such that the water quality of the wastewater containing heavy metal from different processes is homogenized. The homogenized wastewater containing heavy metal is subjected to an anaerobic-aerobic circulating treatment in a membrane bioreactor (2), in which heavy metal ions are reduced by the action of microorganisms in the anaerobic treatment process. The membrane bioreactor (2) is filled with a hollow fiber membrane (3) containing a quinone group, which serves as an electron mediator that can accelerate the enzymatic reduction of heavy metal ions during the anaerobic treatment. During the aerobic treatment, the COD and SS in the wastewater are further removed.