The invention relates to valve system for controlling a process fluid within a liquid processing system. The valve system comprises a valve arrangement, a pneumatic control system, and a connector unit. When the valve arrangement is connected to the connector unit, two or more valves are formed, such that the pneumatic control system controls an open/close or pressure control mode of the valves. A pump diaphragm system is disclosed, as well as a system for purifying a biological material that comprises the valve system or the pump diaphragm system. Also discloses are methods of using the valve system or the pump diaphragm system in a process for the purification of a biological material.

A filter assembly includes a manifold having a fluid inlet and a fluid outlet, a filter housing having a filter medium provided therein, the filter medium defining an inner filter chamber and defining an outer filter chamber between the filter medium and the filter housing, the filter housing being removably attached to the manifold so as to provide a fluid flow path from the inlet into the inner filter chamber, through the filter medium into the outer chamber and out of the outlet. The filter assembly further includes a valve assembly mounted inside the manifold that includes a valve piston and a valve spring arranged in engagement with the valve piston to bias the valve piston into a first position and to compress, in response to a pressure differential across the valve piston exceeding the spring force, to move the valve piston to a second position.

A filter arrangement for an aquarium is disclosed. The filter arrangement can include a filter housing assembly, a pump assembly, and a transfer tube assembly. In one aspect, the housing assembly and the pump assembly are separately constructed assemblies that are connected to each other via a first dampening member to prevent vibration and sound from being transmitted from the pump assembly to the filter housing assembly. The filter arrangement can further include a second dampening member connecting the pump assembly with the transfer tube assembly to further prevent vibration and sound from being transmitted from the pump assembly to the filter housing assembly. A third dampening member can be provided at a location where the transfer tube assembly is supported within the filter housing assembly to further isolate vibration and sound from being transmitted from the pump assembly to the filter housing assembly via the transfer tube assembly.

A separatory funnel for the work up of chemical reactions, extraction or separation of liquid phases. The separatory funnel has multi-functional features, which can be used as regular separatory funnels, Erlenmeyer flasks, and filter funnels. A method is also provided of separating a mixture of at least two immiscible liquids with solids or precipitates so that the clear liquids can be separated.

A single-use device for separating or purifying a large volume of a mixture of substances including membrane chromatography modules which are fixedly mounted in a predetermined grid and a line system for linking the membrane chromatography modules and for connecting the membrane chromatography modules to each other. A cover or bottom mechanism holding the membrane chromatography modules in position in a predetermined grid may be attached to the upper or lower side of the membrane chromatography modules. At least part of the line system is formed in the cover or the bottom mechanism, with connecting lines between the membrane chromatography modules. In a method of separating or purifying a large volume of a mixture of substances using such a single-use device having a plurality of automated valves and sensors connected to a control unit, the automated valves are controlled based on an evaluation of the parameters measured by the sensors.

A filter assembly includes a ring of filter media, a first end cap, a second end cap, a first seal, and a second seal. The first end cap is coupled to a first end of the filter media. The second end cap is coupled to a second end of the filter media and includes (i) a radially extending portion having a first opening and (ii) a first axially extending portion having a stepped ledge defining a first inner diameter. The first seal is supported by the second end cap and includes a second opening defining a second inner diameter that is less than the first inner diameter. The second seal is supported by the second end cap and includes a third opening defining a third inner diameter that is greater than the first and second inner diameters. The stepped ledge is disposed between the first seal and the second seal.

A base station (1) and a bioprocess system (3), wherein said base station (1) comprises: a frame or housing (5), wherein said frame or housing comprises a number of valves (7a-f, 9a-d, 11a-f, 13a-e, 15a-f) into which a disposable tubing set (21) during run of the system is provided such that at least one inlet (23a-j) of the disposable tubing set is connected to at least one outlet (25a-f) of the disposable tubing set via a bioprocess separation device (31) of the bioprocess system (3); and a movable pump holding device (35), which can be provided in at least two different positions, whereof one is within the frame or housing (5) and another is at least partly outside the frame or housing (5) and which comprises at least one pump main body (37), said pump main body comprising a connection (39) configured for connecting to a disposable pump connection part (27) comprised in the disposable tubing set (21).

A separating system and method, of which the separating system includes a lower vessel including an inlet configured to receive a mixed fluid comprising a solid and a liquid. The lower vessel is configured to separate at least some of the solid from the liquid so as to produce a partially-separated fluid. The system also includes a first screen vessel configured to receive at least a portion of the partially-separated fluid, the first screen vessel including a first shell, and a first screen that is positioned within the first shell and at least partially removable therefrom, and a second screen vessel spatially oriented parallel to the first screen vessel and configured to receive at least a portion of the partially-separated fluid. The second screen vessel includes a second shell and a second screen that is positioned within the second shell and is at least partially removable therefrom.

Systems and methods for filter orientation on a control valve are provided. In particular, systems and methods are provided for rotationally orienting a filter retention feature with respect to an application fluid passageway to control forces and stresses exerted on the filter retention feature. Additionally, methods for manufacturing a control valve are provided that enable a rotational relationship between a filter retention feature and an application fluid passageway to be constrained.

A reusable fluid filter system is disclosed. The fluid filter system includes a reusable fluid filter unit that encloses a filter and is removably connected to a manifold. In an embodiment, the filter unit includes an end cap that is detachable so as to replace the filter inside the filter unit. In an embodiment, the filter unit removably engages a valve in the manifold that controls flow paths in the manifold.