The disclosure relates to systems, devices, and methods for flow control in a reverse osmosis filtration system, such as within a medical device. The systems, devices, and methods can respond to changes in permeate flow rate and solute concentration by adjusting feed water and concentrate water rates. Multiple feedback loops adjust parameters to meet water flow rate and purity requirements.

The disclosure relates to systems, devices, and methods for flow control in a reverse osmosis filtration system, such as within a medical device. The systems, devices, and methods can respond to changes in permeate flow rate and solute concentration by adjusting feed water and concentrate water rates. Multiple feedback loops adjust parameters to meet water flow rate and purity requirements.

Systems and methods for filtering materials from biologic fluids are discussed. Embodiments may be used to filter cerebrospinal fluid (CSF) from a human or animal subject. In an example, CSF is separated into a permeate and retentate using a tangential flow filter. The retentate is filtered again and then returned to the subject with the permeate. During operation of the system, various parameters may be modified, such as flow rate and waste rate.

The present invention provides a fresh water generator operating method and a determination program that are employed in a method for cleaning a separation membrane module following membrane filtration, and that, while various cleaning steps such as reverse pressure cleaning, air cleaning, chemical solution cleaning are taking place after completion of the membrane filtration, determines cleaning troubles by calculating a temporal change in resistance increase rate on the basis of an increase in membrane differential pressure.

The utility solution provides the reverse osmosis water purifier (Reverse Osmosis—RO), more specifically the RO water purifier using a module to assist in diagnosing and protecting the good status of the product to assist users to monitor the good status of the machine, assisting technicians in quickly diagnosing the location of faulty components on the system.

The utility solution provides the reverse osmosis water purifier (Reverse Osmosis—RO), more specifically the RO water purifier using a module to assist in diagnosing and protecting the good status of the product to assist users to monitor the good status of the machine, assisting technicians in quickly diagnosing the location of faulty components on the system.

The present disclosure relates to a water purification apparatus that comprises a reverse osmosis device, RO-device, producing a purified water flow and to a corresponding method. The proposed method comprises detecting at least one fluid property of purified water in the purified water path and regulating a flow rate of water in the recirculation path to fulfill one or more predetermined criteria of the purified water in the purified water path, based on the at least one detected fluid property. The present disclosure also relates to a computer program and a computer program product implementing the method.

This present disclosure provides a process for concentrating proteins including an ultrafiltering, a diafiltering, and a second ultrafiltering sequence, at elevated temperatures, such as above about 30° C. The disclosure also includes a process of preparing highly concentrated antibody compositions. and highly concentrated antibody products.

A crossflow filter includes a rigid cylindrical inner wall and a rigid cylindrical outer wall inner with an inelastic filter membrane positioned therebetween defining a retentate channel inside the filter membrane and a permeate channel outside the filter membrane. Further, the filter includes transition channels shaped and connected to the inner and outer walls to deliver a flow of fluid from an inlet port to the retentate channel and to capture flow flowing longitudinally along the cylindrical inner and outer walls from both the retentate and permeate channels to respective outlet ports.

Systems and methods for filtering materials from biologic fluids are discussed. Embodiments may be used to filter cerebrospinal fluid (CSF) from a human or animal subject. In an example, CSF is separated into a permeate and retentate using a tangential flow filter. The retentate is filtered again and then returned to the subject with the permeate. During operation of the system, various parameters may be modified, such as flow rate and waste rate.