A method of removing carbon dioxide from a carbonate-containing diaminoalkane solution, the method including passing the carbonate-containing diaminoalkane solution through a membrane module, and a method of preparing diaminoalkane including the same.

Systems and methods for separating a liquid mixture are disclosed. A membrane is first soaked by the liquid mixture via dynamic soaking to reach steady state. During the soaking process, the flow rate of the liquid mixture is increased at a flow rate ramp, the temperature is increased at a temperature ramp, and the pressure drop is increased at a pressure drop ramp. After the soaking process, the liquid mixture is separated by the membrane under optimized conditions to produce a permeate and a retentate.

Process for producing a finished product containing or consisting of a purified allergenic extract, the process comprising the steps of: (A) providing a crude allergenic extract, the crude allergenic extract being obtained by isolation from a biological sample; (B) optionally, cleaning the crude extract, to obtain a clean crude extract, the cleaning step comprising the sub-steps of (B1) filtering the crude extract to remove the microbial load native to the biological sample; (C) optionally, purifying the crude extract or the clean crude extract, to obtain a purified extract, the purification step comprising the sub-steps of (C1) filtering the crude extract or the clean crude extract to remove impurities having a molecular weight 5,000 Da; the process being characterized in that it comprises a viral ultrafiltration step functional to obtain a finished product substantially free of virus and/or mycoplasma, which contains or consists of a purified extract of the allergen.

The patent application also concerns products for medical use or for diagnostic use, comprising one or more allergen extracts substantially free of viruses and/or mycoplasmas native to the starting biological sample or from any external contamination.