Systems and methods for filtering materials from biologic fluids are discussed. Embodiments may be used to filter cerebrospinal fluid (CSF) from a human or animal subject. The method may include the steps of withdrawing fluid comprising CSF, filtering the volume into permeate and retentate by passing the fluid through a tangential flow filter, and returning the permeate to the subject. During operation of the system, various parameters may be modified, such as flow rate.

A ceramic filter membrane module enables a fluid to be filtered, such as raw water, with higher efficiency using multiple ceramic filters in a housing. As the diameter of a through-hole located at the center is considerably larger than the diameter of the surrounding flow path, water pressure pushing the raw water is applied from the through-hole at the center toward the outside of a filter body, such that the raw water passes through the filter body smoothly, thereby improving the purification efficiency and uniformly setting the overall flow direction of the raw water. As packing members are installed and fixed between the housing and the ceramic filters, sealing of the incoming raw water and the filtered water becomes more effective, such that the risk of leakage is reduced. As a plurality of ceramic filters are housed in a single housing, economic benefit can be achieved.

A full-effective reverse osmosis membrane element and a water purification machine are provided. The reverse osmosis membrane element includes a reverse osmosis membrane (20) and a central tube (10) provided with several water-inlet holes (11). The reverse osmosis membrane (20) is wound around the central tube (10) and covers each water-inlet hole (11) and forms a raw water flow channel. Two sides of the reverse osmosis membrane (20) are sealed by first and second water division bands (21) (22). The first water division band (21) and the central tube (10) form a first concentrated water-outlet (211). The first water division band (21) and the reverse osmosis membrane (20) form a second concentrated water-outlet (212). The second water division band (22) and the reverse osmosis membrane (20) form a first raw water-inlet (221). The second water division band (22) and the central tube (10) form a second raw water-inlet (222).

A hollow fiber membrane module (100) of the present disclosure includes: a plurality of hollow fiber membranes (10); a binding portion (20) binding the plurality of hollow fiber membranes (10) at one end portions thereof; and a cap (30) having an internal space (30s) that communicates with each of the plurality of hollow fiber membranes (10), the cap (30) being integrated with the binding portion (20). Specifically, no other component is present between the binding portion (20) and the cap (30).

The present invention provides a method for hemodiafiltration which applies dialysate gradient across a multi-chambered hemodiafiltrator having a plurality of compartmentalized tubular dialysate chambers. An acidic dialysate with urea at a concentration is applied to a first dialysate chamber. A less acidic dialysate with a lower concentration of urea than those for the first dialysate chamber is applied to a second dialysate chamber. A basic dialysate with no urea but with ammonia at a concentration up to a concentration detected in normal human blood is applied to a last dialysate chamber. The concentrations of urea for the first and second dialysate chambers decrease over time to zero prior to conclusion of hemodiafiltration.

A frit comprising a plurality of grooves; a drain hole; a transverse crossing lane; wherein said plurality of grooves are substantially parallel to one another and extend longitudinally across said frit; wherein said plurality of grooves comprise at least two different lengths; wherein said transverse crossing lane is substantially perpendicular to said plurality of grooves; wherein said drain hole is located within said transverse crossing lane; wherein said drain hole is located at a center of said transverse crossing lane.

A frit comprising a plurality of grooves; a drain hole; a transverse crossing lane; wherein said plurality of grooves are substantially parallel to one another and extend longitudinally across said frit; wherein said plurality of grooves comprise at least two different lengths; wherein said transverse crossing lane is substantially perpendicular to said plurality of grooves; wherein said drain hole is located within said transverse crossing lane; wherein said drain hole is located at a center of said transverse crossing lane.

A water treatment apparatus is provided. The water treatment apparatus includes a filtering unit including a water filter filtering raw water, a sterilizing water generator producing sterilizing water from purified water filtered by at least a portion of the filtering unit, and a discharge member through which the purified water, filtered by the filtering unit, is discharged externally. The sterilizing water produced in the sterilizing water generator sterilizes the discharge member and at least a portion of a flow path connected to the discharge member.

Provided is a spiral membrane module which is suitable for being set up in the vertical direction since at one end of its pressure vessel, the supply of feed liquid and the discharge of concentrated liquid can be attained.

A water treatment device includes a tubular member configured to allow water to flow between an inlet on one end side and an outlet on the other end side, and a filter member disposed in the tubular member between the inlet and the outlet. The filter member includes a conductive filter having permeable holes through which water can flow, a pair of electrodes configured to apply a voltage to the conductive filter, and an insulator disposed between the pair of electrodes and configured to insulate between the pair of electrodes.