A reverse osmosis system includes a wheel formed of a hollow central hub, radial tubes fluidly connected to the central hub, semi-permeable membranes provided in each radial tube, a permeate outlet tube, and a concentrate outlet tube; a permeate collection tank; a concentrate collection tank; and a drive mechanism. The drive mechanism rotationally drives the wheel while the source liquid is supplied to the central hub of the wheel, the rotation causing the source liquid to enter the radial tubes in radially outward directions and cause pressure increase on the source liquid in the radial tubes. The pressure increase forces the source liquid through the semi-permeable membranes to separate into permeate and concentrate, the permeate being directed to the permeate collection tank through the permeate outlet tube and the concentrate being directed to the concentrate collection tank through the concentrate outlet tube.

An acidic gas separation device includes: a first separation device which has an inorganic separation membrane and is configured to separate a gaseous hydrocarbon fluid containing an acidic gas into a first gaseous fluid having a large acidic gas content and a second gaseous fluid having a smaller acidic gas content than the first gaseous fluid by the inorganic separation membrane; and a second separation device which has an organic polymer separation membrane and is configured to separate the second gaseous fluid into a third gaseous fluid having a large acidic gas content and a fourth gaseous fluid having a smaller acidic gas content than the third gaseous fluid by the organic polymer separation membrane.

Provided herein are, inter alia, biological manufacturing and downstream purification processes.

A separation membrane module may decrease a bending load applied to a support member supporting ends of tubular separation membranes and omission of a seal member between the outer circumferential surface of the support member and the inner circumferential surface of a housing. The separation membrane module may include a tubular housing, tubular separation membranes arranged in a longitudinal direction of the housing, end tubes connected to lower ends of the tubular separation membranes, a support box supporting the end tubes, and a backpressure chamber below the support box. The tubular separation membranes may be in communication with a support box collection chamber. A nozzle disposed on the support box may extract permeated fluid. A chamber and the backpressure chamber are in communication via a gap between the support box outer circumferential surface and the inner circumferential surface. The chamber and backpressure chamber have substantially the same pressure.

Provided herein are, inter alia, biological manufacturing and downstream purification processes.

A liquid treatment system, in particular for concentrating milk, and method therefor. The system includes an inlet configured to receive fresh raw milk; and a pressure vessel connected to the inlet. The pressure vessel is provided with a pressure system configured to realize a pressure of at least 10 bar in the pressure vessel. A reverse osmosis membrane is included for filtering the raw milk. A pump is provided for pumping the raw milk under pressure out of the pressure vessel and through or along the reverse osmosis membrane. A permeate outlet is provided for the separated water and a milk outlet is provided for the concentrated milk.

A gas separation system for controlling a concentration of a first gas species and a second gas species in an outlet gas comprises a splitter unit. The splitter unit comprises a gas membrane system having a gas inlet port. The gas inlet port is in fluid connection with an air intake. A membrane is a selective barrier and allows some things to pass through but stops others.

One aspect of the invention provides a method of separating long polynucleotides from a composition. The method includes: introducing a composition including one or more long polynucleotides into a container including at least one boundary defined by a filter comprising a plurality of pores, wherein the pores have a smaller cross-sectional dimension than specified for the long polynucleotide's molecular weight; and applying elevated hydraulic pressure to the composition, thereby causing at least some of the one or more long polynucleotides to pass through the pores.

A separation membrane module that is provided enables a bending load that is applied to a support member that supports ends of tubular separation membranes to be decreased and enables a seal member between the outer circumferential surface of the support member and the inner circumferential surface of a housing to be omitted. The separation membrane module includes a tubular housing 2, tubular separation membranes 3 that are arranged in a longitudinal direction of the housing 2, end tubes 4 that are connected to the lower ends of the tubular separation membranes 3, a support box 5 that supports the end tubes 4, and a backpressure chamber 16 below the support box 5. The tubular separation membranes 3 are in communication with a collection chamber 5v of the support box 5. A permeated fluid is extracted via a nozzle 5n that is disposed on the support box 5. A chamber 11 and the backpressure chamber 16 are in communication with each other via a gap between the outer circumferential surface of the support box 5 and the inner circumferential surface of the housing 2. Pressure in the chamber 11 and pressure in the chamber 16 are substantially the same.

Provided herein are, inter alia, biological manufacturing and downstream purification processes.