A tangential flow filtration manifold takes a modular form for interconnection in a manifolded arrangement for aggregating a total filtration area of the aggregate filter (membrane) surface. A plurality of modular TFF cassette filters may be or stacked on the TFF manifold such that it allows the number of interconnected filters, as well as the membrane surface area within each cassette, to be readily reconfigured. A single output, or filtrate connection on the TFF manifold simplifies fluidic plumbing connections for directing and gathering the filtrate (permeate) produced as output.

The present disclosure relates to tangential flow filters, membranes, and ultrafiltration membranes, for various applications, including bioprocessing and pharmaceutical applications, systems employing such filters, and methods of filtration using the same. In an aspect, an alternating tangential flow system for continuous processing may include a feed line containing a fluid. A retentate line may be in fluid communication with the feed line. A first diaphragm may be at an inlet of the retentate line configured to pump fluid toward an outlet of the retentate line. A second diaphragm may be at the outlet of the retentate line configured to pump fluid toward the inlet of the retentate line. A membrane may be in fluid communication with the retentate line between the first diaphragm and the second diaphragm. A retentate pump may be at the retentate outlet configured to pump the fluid out of the retentate line.

The present invention includes: a first sealing portion which has a first entry/exit selectively opened or closed by a first opening/closing valve and a second entry/exit selectively opened or closed by a second opening/closing valve and is configured to seal one end of a housing; a second sealing portion which has a third entry/exit selectively opened or closed by a third opening/closing valve and a fourth entry/exit selectively opened or closed by a fourth opening/closing valve, and is configured to seal the other end of the housing; and a controller which is configured to control the supply of raw water through any one of the first entry/exit and the second entry/exit or control the supply of raw water through any one of the third entry/exit and the fourth entry/exit.

Tangential flow filtration systems utilizing flexible bags for permeate collection are provided.

The disclosure relates to systems and methods for improving the manufacturing of silk solutions and powders containing silk fibroin obtained from silkworm cocoons. The solutions and powders can be used to improve the post-harvest preservation of perishables and to improve the performance of packaging, including biodegradable packaging.

An automated modular filtration system, particularly for low volume tangential flow filtration processes, comprises a plurality of filtration modules formed as separate assemblies and at least one control unit for jointly controlling filtration processes of individual filtration units. Each filtration module contains at least one individual filtration unit for executing a filtration process independent of the other filtration units, first input ports for receiving a first type of fluids, second input ports for receiving a second type of fluids, and exit ports for outputting unused system fluids. First type fluids are process fluids are specific to the filtration processes executed in individual filtration units. Second type fluids are system fluids not specific to filtration processes executed in the individual filtration units. The second input and exit ports establish inter-module connections so system fluids can be forwarded from one filtration module to an adjacent filtration module of the filtration system.

A filtration system can include a loading member configured to receive a plurality of filtration members which can be sequentially moved from a non-active position in which a respective one of the plurality of filtration members is not in fluid communication with a sample flow path of the cell removal system, to an active position in which the respective filtration member is in fluid communication with the sample flow path, and to a discarded position in which the respective filtration member has been removed from fluid communication with the sample flow path.

A modular element for making reverse osmosis filtering devices includes: at least one first container and a second container, each of which is provided with a tubular lateral wall, with a bottom plate which closes a first axial end of said lateral wall, with an inlet, with a first outlet and with a second outlet, the first and second containers being arranged so that the respective lateral walls are arranged adjacent and have mutually parallel central axes, and a scavenging duct which connects the second outlet of the first container with the inlet of the second container, the first container, the second container and the scavenging duct are obtained as a single monolithic body.

Disclosed is a method of manufacturing an air separation module (ASM) of a nitrogen generation system (NGS), the method providing: determining an at least partially nonlinear shape between opposing ends of a canister, the canister being configured to fit within an installation envelope for the ASM in the NGS and configured to have installed therein an air separating membrane; and additively manufacturing the canister.

A method for preparation of conductive polymer/carbon nanotube (CNT) composite nanofiltration (NF) membrane and the use thereof. This conductive polymer/CNT composite NF membrane is obtained by polymerizing conductive polymer into a CNT membrane and then in-situ cross-linking with glutaraldehyde under acidic condition. The synthetic method for the conductive polymer/CNT composite NF membrane is simple and has no need of expensive equipment. The prepared membrane has controllable membrane structure and possesses superior electrical conductivity and electrochemical stability. The membrane can couple with electrochemistry for electrically assisted filtration. With the electrical assistance, the membrane can achieve improved ion rejection performance while retaining high permeability by enhancement of membrane surface charge density, which alleviates the permeability-selectivity trade-off. Furthermore, the electrically assisted NF membrane filtration can also enhance the removal for small molecular organic pollutants.