A liquid handling device having an axis of rotation about which the device can be rotated to drive liquid flow in the device. The device includes an upstream chamber having an outlet, a downstream chamber including a proximal portion radially inwards of a distal portion and including a first port disposed in the distal portion and a first conduit which connects the outlet of the upstream chamber to the first port of the downstream chamber. The first conduit extends radially inwards to a crest and radially outwards from the crest to the first port of the downstream chamber. A distance between the axis of rotation and the crest is greater than or equal to a distance between the axis of rotation and the outlet of the upstream chamber.

A liquid handling device having an axis of rotation about which the device can be rotated to drive liquid flow in the device. The device includes an upstream chamber having an outlet, a downstream chamber including a proximal portion radially inwards of a distal portion and including a first port disposed in the distal portion and a first conduit which connects the outlet of the upstream chamber to the first port of the downstream chamber. The first conduit extends radially inwards to a crest and radially outwards from the crest to the first port of the downstream chamber. A distance between the axis of rotation and the crest is greater than or equal to a distance between the axis of rotation and the outlet of the upstream chamber.

A rotor (10) of a dual centrifuge which can be rotated about a drive axis (A) in a centrifuge, which rotor comprises at least two rotary units (26) that are arranged symmetrically to one another and have a bearing (32) and a rotary head (30) which is connected to the bearing (32) and which is mounted in the bearing (32) so as to be rotatable about a rotational axis (R1, R2), which rotary head (30) can be driven about the rotational axis (R1, R2) relative to the rotor by another rotary mechanism (46) of the centrifuge and has a rotary head receiving unit (80) for at least one sample container or at least one sample container receptacle (100, 110), with the rotational axis (R1, R2) of the rotary head (30) being inclined relative to the drive axis (A) of the rotor, the rotary head receiving unit (80) being designed to receive an elongated sample container receptacle (100, 110) or an elongated sample container, and the longitudinal axis of the sample container receptacle (100, 110) introduced into the rotary head receiving unit (80) or the longitudinal axis of the sample container introduced into the rotary head receiving unit (80) extending perpendicular to the axis of rotation (R1, R2) of the rotary head (30) or being oriented at an angle ranging between more than 0 and less than 90 relative to the axis of rotation. At least one connection region (52) is provided to which at least one damping mass (54) can be selectively attached either in a releasable manner or, by a fixing element, in a permanent manner for operation.

The disclosure provides a solventless method of producing coated botanical substrates by (i) uniformly coating a known exact amount of an active ingredient on the botanical substrates until the ingredient is substantially adsorbed to the surface of the botanical substrate to produce a homogeneous primary coating of the ingredient on the botanical substrates, and optionally (ii) substantially incorporating a flavoring agent with the surface of the plurality of botanical substrates coated with the ingredient.

The disclosure provides a solventless method of producing coated botanical substrates by (i) uniformly coating a known exact amount of an active ingredient on the botanical substrates until the ingredient is substantially adsorbed to the surface of the botanical substrate to produce a homogeneous primary coating of the ingredient on the botanical substrates, and optionally (ii) substantially incorporating a flavoring agent with the surface of the plurality of botanical substrates coated with the ingredient.

A device provides selective modes of vibrational oscillations and centrifugal rotations for preparing analysis samples. The device includes a base, an elastic connection body, a group of a synchronous unidirectional bearing inner ring and a synchronous unidirectional bearing outer ring, a group of an eccentric unidirectional bearing inner ring and an eccentric unidirectional bearing outer ring, and a synchronous fixed ring and a motor on the base. The eccentric unidirectional bearing outer ring is connected to a sample plate for holding the analysis samples.

A mixing device for operating biological, chemical or biochemical materials used in an assay includes a mixing member formed with a plurality of chambers, each having a sealable port provided along an edge of the mixing member. The mixing device also includes one or more compartments that are movable along the edge of the mixing member between selected ones of the sealed chambers. This compartment is operable to receive materials from and transfer materials between the chambers. Selected ones of the chambers include associated processing elements, for example, including heating and cooling elements, magnetic elements, membranes and lateral flow devices. The mixing device is also pivotable, for example, to facilitate the application of gravity force in the transfer of materials between the chambers and one or more compartments. The mixing device may operate manually by hand-held unit. Also, this mixing device may operate automatically with at least one driving unit.

A solvent mixing system includes a mixing tee, a centrifugal mixing path, and a low frequency blending mixer. The mixing tee has at least two solvent input ports and a solvent output port in fluid communication with one another. The centrifugal mixing path has a mixing path inlet in fluid communication with the solvent output port of the mixing tee. The centrifugal mixing path includes at least one coiled segment between the mixing path inlet and a mixing path outlet. The low frequency blending mixer is in fluid communication with the outlet of the centrifugal mixing path.

A solvent mixing system includes a mixing tee, a centrifugal mixing path, and a low frequency blending mixer. The mixing tee has at least two solvent input ports and a solvent output port in fluid communication with one another. The centrifugal mixing path has a mixing path inlet in fluid communication with the solvent output port of the mixing tee. The centrifugal mixing path includes at least one coiled segment between the mixing path inlet and a mixing path outlet. The low frequency blending mixer is in fluid communication with the outlet of the centrifugal mixing path.

A method for mixing fluids in containers may include performing a mixing procedure on a plurality of containers on a container support, at least a portion of the plurality of containers being differently sized. The mixing procedure may include a plurality of mixing phases, wherein in each mixing phase the container support may be subjected to a mixing motion at a single rate for a period of time of about 5 seconds or longer, and wherein the single rate for at least one mixing phase of the plurality of mixing phases may differ from the single rate for at least one other mixing phase of the plurality of mixing phases. The mixing procedure also may include at least one non-mixing phase, wherein the container support may not be subjected to the mixing motion.