Patent classifications
B01F29/15
SYSTEM AND METHOD FOR SOLVENT MIXING IN A CHROMATOGRAPHY SYSTEM
A solvent mixing system includes a mixing tee, a centrifugal mixing path, and a low frequency blending mixer. The mixing tee has at least two solvent input ports and a solvent output port in fluid communication with one another. The centrifugal mixing path has a mixing path inlet in fluid communication with the solvent output port of the mixing tee. The centrifugal mixing path includes at least one coiled segment between the mixing path inlet and a mixing path outlet. The low frequency blending mixer is in fluid communication with the outlet of the centrifugal mixing path.
SYSTEM AND METHOD FOR SOLVENT MIXING IN A CHROMATOGRAPHY SYSTEM
A solvent mixing system includes a mixing tee, a centrifugal mixing path, and a low frequency blending mixer. The mixing tee has at least two solvent input ports and a solvent output port in fluid communication with one another. The centrifugal mixing path has a mixing path inlet in fluid communication with the solvent output port of the mixing tee. The centrifugal mixing path includes at least one coiled segment between the mixing path inlet and a mixing path outlet. The low frequency blending mixer is in fluid communication with the outlet of the centrifugal mixing path.
CENTRIFUGE WITH EXCHANGEABLE ROTORS
The invention relates to a dual centrifuge (10) which has the following: a driveshaft (16), a rotor (20), which is mounted on the driveshaft (16) and which can be removed axially in a removal direction (E), for a dual centrifuge, having at least one rotational unit (30); an opening (18) in the rotor (20), wherein an end region (16a) of the driveshaft (16) at least engages into said opening; and an additional drive mechanism (32) for the rotational unit or the rotational units (30). The dual centrifuge additionally has a design for operating various additional types of rotors; however, only one rotor (20, 40, 50) can be arranged on the driveshaft (16) at all times. The various rotor types (40, 50) are also adapted to the additional drive mechanism (32) for the rotational units (30) such that the function is not adversely affected. The invention is characterized by a design for operating at least one angular head rotor (40) and a swing-out rotor (50). For this purpose, the driveshaft (16) and the various rotor types (40, 50) are adapted to each other. The bearing (16), the driveshaft (16), and the various rotor types (40, 50) are adapted to one another such that each non-dual rotor (40, 50) has a geometry that is measured such that when the rotor (40, 50) is mounted, a drive means (32a) of the additional drive mechanism (32) for the rotational units (30) is arranged so as to not contact the mounted rotor (40, 50).
ROTOR OF A DUAL CENTRIFUGE
The invention relates to a rotor (10) of a dual centrifuge which can be rotated about a drive axis (A) in a centrifuge, which rotor comprises at least two rotary units (26) that are arranged symmetrically to one another and have a bearing (32) and a rotary head (30) which is connected to the bearing (32) and which is mounted in the bearing (32) so as to be rotatable about a rotational axis (R1, R2), which rotary head (30) can be driven about the rotational axis (R1, R2) relative to the rotor by another rotary mechanism (46) of the centrifuge and has a rotary head receiving unit (80) for at least one sample container or at least one sample container receptacle (100, 110), with the rotational axis (R1, R2) of the rotary head (30) being inclined relative to the drive axis (A) of the rotor, the rotary head receiving unit (80) being designed to receive an elongated sample container receptacle (100, 110) or an elongated sample container, and the longitudinal axis of the sample container receptacle (100, 110) introduced into the rotary head receiving unit (80) or the longitudinal axis of the sample container introduced into the rotary head receiving unit (80) extending perpendicular to the axis of rotation (R1, R2) of the rotary head (30) or being oriented at an angle ranging between more than 0 and less than 90 relative to the axis of rotation. According to the invention, at least one connection region (52) is provided to which at least one damping mass (54) can be selectively attached either in a releasable manner or, by means of a fixing element, in a permanent manner for operation.
GRINDING ADAPTER FOR A DUAL ASYMMETRIC CENTRIFUGAL MIXER AND METHOD OF USE THEREOF
An adapter for enabling grinding of one or more materials using a centrifugal mixer, the adapter to be fitted into a container of the centrifugal mixer; it has a body defining an inner compartment, the body including openings; a filter positioned or for positioning around the body; and wherein the inner compartment is configured to receive grinding media for grinding the one or more materials and the openings are adapted to enable the one or more materials to enter and/or leave the inner compartment for grinding by the grinding media when subject to the centrifugal force applied by the centrifugal mixer while maintaining the grinding media in the inner compartment, the filter is adapted to filter the one or more materials that are ground to a size suitable to pass through the filter; a method of use thereof.
GRINDING ADAPTER FOR A DUAL ASYMMETRIC CENTRIFUGAL MIXER AND METHOD OF USE THEREOF
An adapter for enabling grinding of one or more materials using a centrifugal mixer, the adapter to be fitted into a container of the centrifugal mixer; it has a body defining an inner compartment, the body including openings; a filter positioned or for positioning around the body; and wherein the inner compartment is configured to receive grinding media for grinding the one or more materials and the openings are adapted to enable the one or more materials to enter and/or leave the inner compartment for grinding by the grinding media when subject to the centrifugal force applied by the centrifugal mixer while maintaining the grinding media in the inner compartment, the filter is adapted to filter the one or more materials that are ground to a size suitable to pass through the filter; a method of use thereof.
HIGH-SPEED CENTRIFUGAL MIXING DEVICES AND METHODS OF USE
A centrifugal mixing device can include a shaft assembly that is operably coupled to a motor such that the motor rotates the shaft assembly about a first axis. The devices can further include a turret that is rotatably coupled to the shaft assembly such that the turret rotates about the first axis relative to the shaft assembly. The turret can include a first support, a first canister rotatably coupled to the first support such that the first canister rotates about a second axis, and a second canister rotatably coupled to the first support such that the second canister rotates about a third axis. The turret is configured to rotate about the first axis in a first rotational direction and each of the first and second canisters is configured to rotate about the second and third axes, respectively, in a second rotational direction that is opposite the first rotational direction.
RESIN DISPENSING APPARATUS
A resin dispensing apparatus includes a supply unit including a syringe having an internal space configured to hold a phosphor-containing resin. An agitator is disposed in the internal space. The supply unit is configured to rotate at least one of the syringe and the agitator to prevent settling of phosphor contained in the phosphor-containing resin. A discharge unit includes a cylinder having a discharge nozzle through which the phosphor-containing resin, received through a connecting pipe connected to the syringe, is discharged. A piston provides pressure to discharge the phosphor-containing resin through the discharge nozzle inside the cylinder.
Mixer for insertion into a rotor of a centrifuge
A mixer for insertion into a rotor of a centrifuge has a mixing trough and an obstacle device with at least one obstacle. The at least one obstacle is configured in order to influence the flow of a liquid present in the mixing trough. In response to a rotation of the rotor, with a specified incorporation of the mixer in a holder of the rotor, a spacing between at least one wall section of the mixing trough and the obstacle device is variable such that the liquid present in the mixing trough flows around the obstacle of the obstacle device.
Method of encapsulating active ingredients in liposomes
A method for encapsulating active ingredients in liposomes having an active ingredient solution encapsulated with a bilayer composed of two monomolecular layers of amphiphilic compounds comprises: (a) providing the active ingredient solution; (b) providing an emulsion by emulsifying the active ingredient solution in a first liquid in the presence of the amphiphilic compound; (c) providing a liquid phase; (d) contacting the emulsion with the liquid phase to form a phase boundary; and (e) centrifuging the emulsion and the liquid phase that are in contact with one another via the phase boundary, wherein, on passage of the phase boundary, the amphiphilic compound enriched there is added onto the monomolecular inner layer to form a monomolecular outer layer, in order to create the bilayer. The first liquid of the emulsion is chosen such that the solubility of the amphiphilic compound in the first liquid is not more than 110.sup.4 mol/l.