A process for making an oligonucleotide, the process including reacting a oligonucleotide precursor with a solid phase support within a reaction vessel, the reaction vessel being coupled to an actuator and having a resting position and inverting the reaction vessel via the actuator such that the reaction vessel is inverted relative to the resting position, wherein the inversion of the reaction vessel results in stirring of the solid phase support within the reaction vessel.

The present invention relates to a particle manipulation method to disperse magnetic particles 70 in a liquid 35 filling up a tube container 10, wherein a circumferential direction moving step to move the magnetic particles 70 along the circumferential direction of the container 10 in the liquid 35 and in a radial direction moving step to move the magnetic particles 70 as crossing the radial direction of the container 10 in the liquid 35 are implemented repeatedly. Such manipulations can be achieved by combining rotation of the container and gravity force and magnetic field manipulations.

The present invention relates to a mixer and applicator device for mixing and applying a compound obtained by means of mixing two products which comprises: a casing which internally houses a movable push rod, where the casing allows housing a container which is fixed to the casing, a drill or rotor for driving the movable push rod, a base part coupled to a rear portion of the drill or rotor, at least one guide which is secured at a first end on the base part and at a second end on the casing where the ends of the at least one guide are fixed on the casing such that the at least one guide allows the fixing and rotation of the casing, and at least one member going through the at least one guide respectively such that the rotation of the casing does not take place in response to the actuation of the drill or rotor. As a result of this device it is possible, using the same device, to prepare a compound by means of mixing a base product and a catalyst and to further be able to dispense it without having to perform any disassembly or adaptation whatsoever in the container or in the means used for the mixing.

The invention relates to a pretreatment process for improving the filling of a chamber with solid particles, in which said solid particles are mixed before loading of said solid particles into the chamber with at least one lubricant that is solid at ambient temperature chosen from saturated fatty acids having 14 or more carbon atoms, metal salts of saturated fatty acids having 14 or more carbon atoms, esters of fatty acids having 14 or more carbon atoms, fatty alcohols having 14 or more carbon atoms, linear N-alkanes having 16 or more carbon atoms in solid form, fumaric acid, talc, sodium stearoyl fumarate, the lubricant being introduced at a content of between 0.01% and 1% relative to the total weight of the mixture of solid particles and lubricant. The invention also relates to the use of the process for the pretreatment of particles of adsorbents for the separation of xylenes.

A tumbler for food, including a container designed for receiving the food, which comprises a fluid channel for a fluid provided on the jacket side, a removal opening for the food provided on a first end face, a supply opening for the food provided on a second end face situated opposite the first end face and an extraction opening for a gas provided in the container, including a drive for rotating the container around a rotation axis and including a rotary leadthrough assigned to the second end face, which comprises a connection module, a rotary module, which is provided to be rotatable with respect to the connection module and is rotatable around the rotation axis together with the container.

A slide gate assembly includes a mounting plate with a through opening and an upper surface, and a top plate with a through opening and lower surface, wherein the through opening of the top plate aligns with the through opening of the mounting plate. A slide plate is mounted between the lower surface of the top plate and the upper surface of the mounting plate, wherein the slide plate is slidable between a closed position and an open position, wherein, in the closed position the slide plate blocks material passage from the opening of the top plate to the opening of the bottom plate, wherein, in the open position, the slide plate permits material passage from the opening of the top plate to the opening of the bottom plate

A concrete mixer system includes a control system configured to provide a first input to a drum drive system to rotate a drum of a concrete mixer at a target speed while the drum is empty and clean, acquire operating data regarding an operating characteristic of the drum drive system to determine a baseline operating characteristic of the drum drive system in response to the first input, provide a second input to the drum drive system to rotate the drum at the target speed following one or more uses of the concrete mixer and while the drum is empty, acquire the operating data to determine a current operating characteristic of the drum drive system in response to the second input, and provide a buildup notification indicating that there is a buildup of drum contents within the drum in response to a difference between the baseline operating characteristic and the current operating characteristic exceeding a threshold differential.

A technique for reducing stagnation of food at a specific location on a drum when food is stirred using the drum is disclosed. The disclosed food stirring device includes: a drum that extends in an axial direction, has a hollow shape, and includes: an inlet part through which a food to be fed to an inside of the drum passes; and an outlet part that is provided at a position different from the inlet part and through which the food to be discharged from the inside of the drum passes; a drum drive device that rotates the drum around a rotation axis; a stirrer that is at least partially located inside the drum; and a support member that is attached to the drum and supports the stirrer, wherein there is a gap between an inner wall surface of the drum and the stirrer, and wherein a ratio of a shortest diameter to a longest diameter of a cross sectional surface, in a direction perpendicular to the axial direction, of a part of the stirrer that is located inside the drum is 1/3 or greater and 1 or less.

A technique for reducing stagnation of food at a specific location on a drum when food is stirred using the drum is disclosed. The disclosed food stirring device includes: a drum that extends in an axial direction, has a hollow shape, and includes: an inlet part through which a food to be fed to an inside of the drum passes; and an outlet part that is provided at a position different from the inlet part and through which the food to be discharged from the inside of the drum passes; a drum drive device that rotates the drum around a rotation axis; a stirrer that is at least partially located inside the drum; and a support member that is attached to the drum and supports the stirrer, wherein there is a gap between an inner wall surface of the drum and the stirrer, and wherein a ratio of a shortest diameter to a longest diameter of a cross sectional surface, in a direction perpendicular to the axial direction, of a part of the stirrer that is located inside the drum is 1/3 or greater and 1 or less.

An agitation device includes a holder that holds a cartridge containing a liquid on a placement surface angled with respect to a horizontal plane; and a rotator that rotates the holder to agitate the liquid.