A method, apparatus, and system for mixing a compounded material. A first selected amount of a base part for the compounded material and a second selected amount of an activator part for the compounded material to form a total amount of the compounded material is determined. The first selected amount of the base part is pumped by a pump system from a set of base part sources connected to the pump system into a container. The second selected amount of the activator part is pumped by the pump system from a set of activator part sources connected to the pump system into a container. The base part and the activator part in the container are mixed by a mixing system for a predetermined amount of time that is sufficient to activate the compounded material for use.

A container for bone cement includes a first member defining a chamber, which contains a first ingredient. The chamber also includes a second member movably coupled to the first member. The second member includes a mixing device that is movably disposed within the first chamber, and the second member defines a second chamber containing a second ingredient. The container additional includes an opening device that selectively opens the second chamber and allows the second ingredient to enter from the second chamber into the first chamber. The mixing device is movable within the first chamber to promote mixing of the first ingredient and the second ingredient to prepare the bone cement. A corresponding method of preparing bone cement is also disclosed.

A capped retail dispenser package encloses and retains a mixing container into which a product mixture is filled using an automated manufacturing system in an individualized manner, such that each individual product container may be charged with a customized or unique formulation different than a previous or subsequent container passing through the system. Mixing is not done prior to filling, but with a mixer received in a slidable bottom portion that functions as a piston. The rod terminates at its upper end with a mixing plate. Movement of the rod through the central opening provides mixing of the product through a reciprocating motion, and preferably with a simultaneous rotation. Movement of the upper mixing plate within the mixing container provides mixing of the container's contents by forcing fluid flow through one or more mixing apertures formed about a flange of the mixing plate.

A capped retail dispenser package encloses and retains a mixing container into which a product mixture is filled using an automated manufacturing system in an individualized manner, such that each individual product container may be charged with a customized or unique formulation different than a previous or subsequent container passing through the system. Mixing is not done prior to filling, but with a mixer received in a slidable bottom portion that functions as a piston. The rod terminates at its upper end with a mixing plate. Movement of the rod through the central opening provides mixing of the product through a reciprocating motion, and preferably with a simultaneous rotation. Movement of the upper mixing plate within the mixing container provides mixing of the container's contents by forcing fluid flow through one or more mixing apertures formed about a flange of the mixing plate.

An apparatus for mixing bone cement can comprise a receiving chamber, a mixing chamber, a cannula, a base, and a piston located within the mixing chamber. The receiving chamber defining a conduit. The mixing chamber in fluid communication with the receiving chamber. The mixing chamber configured to house a first component of the bone cement. The cannula located in the receiving chamber and in fluid communication with the conduit. The base including a bladder arranged to be punctured by the cannula, the bladder configured to house a second component of the bone cement. Upon puncturing of the bladder by the cannula the second component of the bone cement passes through the conduit and the cannula into the mixing chamber. The piston configured to seal the mixing chamber upon movement of the piston from a first position relative to the conduit to a second position relative to the conduit.

Mixers for adhesives and sealants that include automatic stroke length adjustment for different sizes and configurations of adhesive and sealant cartridges are disclosed. The mixers include a sensor for detecting when a mixing impeller reaches the top of a cartridge and the bottom of a cartridge, which sends a signal to a main pressure cylinder to reverse direction. The stroke length of the mixer is automatically adjusted without the necessity of manual selection based upon a particular cartridge size.

A storage and mixing device for PMMA bone cements having a cylindrical interior of the cartridge that is delimited on a front side by a cartridge head with a closed delivery opening, a plunger which is arranged to be axially movable in the cylindrical interior of the cartridge and which is spaced from the cartridge head. The plunger circumferentially rests against the inner wall of the interior, so that the plunger divides the interior of the cartridge into two sections in a gas-tight manner, a powdery first parent component of the bone cement, which is contained in the interior between the plunger and the cartridge head, a feed-through which is arranged in the cartridge head or in the cylinder barrel of the cartridge between the plunger and the cartridge head, wherein the feed-through is connected to a fluid line in which a monomer liquid as a second parent component of the bone cement is contained or into which a monomer liquid is fillable or introducible. A filter is arrangeable in the cartridge head, in the feed-through and/or in the fluid line, wherein the filter is permeable to the monomer liquid and impermeable to the first parent component, wherein the plunger is spaced from a back side of the cylindrical interior, located opposite the front side, to an extent that, by moving the plunger in the direction of the back side, a reduced pressure is producible in the interior of the cartridge between the plunger and the cartridge head, wherein the reduced pressure is able to suck the monomer liquid out of the fluid line into the interior of the cartridge.

The present disclosure discloses a method for preparing a pure chitosan fiber, and relates to the technical field of preparation of chitosan. The method includes the following steps: S1, preparing an acetic acid solution; S2, preparing a chitosan stock solution; S3, treating a chitosan spinning solution; and S4, preparing a chitosan fiber. In step S3, a pretreatment machine includes a body; an driving mechanism is arranged in the body; a stirring mechanism is arranged in the driving mechanism; a scraping mechanism is arranged below the driving mechanism; a preliminary treatment mechanism is arranged at an inner upper side of the body; the driving mechanism penetrates through the preliminary treatment mechanism and is arranged in the body; a separation mechanism is arranged on a bottom of the body.

A liquid handling system for use with a liquid sample in a container includes a probe and an actuator. The probe is configured to be inserted into the container to contact the liquid sample in the container. The probe has a probe axis. The probe includes an elongate probe body having a distal end, and an integral mixing device on the probe body proximate the distal end. The actuator is operable to reciprocate the probe in the container along the probe axis such that the mixing device generates mixing currents in the liquid sample.

One aspect relates to a bone cement applicator having a cartridge with an interior, a cartridge head with a delivery opening, a mixing member which is movable in the interior with a mixing rod. A delivery plunger is arranged in the cartridge and is mounted in the interior and is pressable in the direction of the delivery opening. The delivery plunger rests with an outer cylindrical circumferential surface against an inner wall of the cartridge. A clamping element is arranged on the inner wall of the cartridge in the region of a back side of the interior. The clamping element projects out of the inner wall of the cartridge. The cylindrical circumferential surface of the delivery plunger is resiliently deformable by the clamping element in the direction of a central cylinder axis, such that the delivery plunger is clampable in place with the at least one clamping element on the back side of the cartridge.