The present invention relates to extended release microparticles comprising a drug, and a preparation method therefor, and when the extended release microparticles comprising a drug are administered in order to replace conventional drugs that should be administered daily or monthly, the drug administration effect can be continuously maintained for one week to three months. In addition, the drug administration effect is maintained for a long time and, simultaneously, microparticles are prepared so as to have the average diameter of a fixed micro-size, and thus an effective drug concentration can be constantly maintained by controlling the release of the drug from the microparticles, and a foreign body sensation and pain can be reduced during drug administration since microparticles having a uniform size are included during application as an injectable drug.

In a channel structure of a channel device, first confluence channels of a plurality of first channels include a plurality of first confluence channels arranged along a second board front surface, first confluence portions of the first channels in each of first boards are configured of a plurality of first confluence portion through-holes that penetrate the first board, and second first-liquid introduction channel and second second-liquid introduction channels of a plurality of second channels are arranged along the second board front surface and are located in an area that is deviated from the first confluence channels in a view in a direction along a stacking direction of the first board and the second board.

An apparatus and a method for manufacturing instantly emulsified cosmetics is disclosed. The apparatus comprises: a housing; a pump in the housing for discharging an instantly emulsified emulsion outside of the housing; a first container in the housing for storing an internal fluid; a second container in the housing for storing a functional fluid including a functional raw material; a third container in the housing for storing an external fluid; a channel part in the housing for receiving the external fluid, the internal fluid and the functional fluid generate an emulsion; and a tube provides the pump with the emulsion generated in the channel part, wherein the channel part includes: a first channel for mixing the internal fluid and the functional fluid to generate a mixed fluid; and a second channel for mixing the mixed fluid provided from the first channel and the external fluid to generate an emulsion.

Embodiments include microfluidic devices and related methods. A microfluidic device for producing microbubbles may include a first microfluidic channel for supplying a continuous phase fluid, the first microfluidic channel including a convergent section and a constant-width section downstream from the convergent section, wherein the constant-width section discharges into a junction; a second microfluidic channel for supplying a dispersed phase fluid, the second microfluidic channel including an orthogonal section oriented orthogonal to the constant-width section, wherein the orthogonal section discharges into the junction; and a third microfluidic channel for conveying produced microbubbles, the third microfluidic channel including a divergent section, wherein the junction discharges into the divergent section.

Embodiments include microfluidic devices and related methods. A microfluidic device for producing microbubbles may include a first microfluidic channel for supplying a continuous phase fluid, the first microfluidic channel including a convergent section and a constant-width section downstream from the convergent section, wherein the constant-width section discharges into a junction; a second microfluidic channel for supplying a dispersed phase fluid, the second microfluidic channel including an orthogonal section oriented orthogonal to the constant-width section, wherein the orthogonal section discharges into the junction; and a third microfluidic channel for conveying produced microbubbles, the third microfluidic channel including a divergent section, wherein the junction discharges into the divergent section.

The application relates to microfluidic apparatus and methods of use thereof. Provided in one example is a microfluidic device comprising: a first fluidic input and a second fluidic input; and a fluidic intersection channel to receive fluid from the first fluidic input and the second fluidic input, wherein the fluidic intersection channel opens into a first mixing chamber on an upper region of a first side of the first mixing chamber, wherein the first mixing chamber has a length, a width, and a depth, wherein the depth is greater than about 1.5 times a depth of the fluidic intersection channel; an outlet channel on an upper region of a second side of the first mixing chamber, wherein the outlet channel has a depth that is less than the depth of the first mixing chamber, and wherein an opening of the outlet channel is offset along a width of the second side of the first mixing chamber relative to the fluidic intersection.

Provided is an apparatus for generating a microfluidic concentration field, the apparatus including: a substrate; a base film disposed on the substrate; a microchannel, which is formed in a space between the substrate and the base film and through which a fluid flows; a through passage, which communicates with the microchannel and is configured to pass through the base film; and a membrane, which is formed at a portion where the microchannel and the through passage communicate with each other and allows the fluid flowing along the microchannel and the through passage or a material flowing together with the fluid to selectively pass through the membrane, wherein a concentration field is formed between the fluid of the through passage and the fluid of the microchannel by the membrane.

A chemical reactor/mixer, in particular for producing hydrates comprising a mixer network plate and heat exchanger plates wherein the network mixer plate comprises an array of chambers that are connected by channels where the flow of one or more fluids is mixed and divide sequentially. The network mixer plate is confined by the heat exchanger plate that have an inner chamber where a heat exchanger fluid is introduced. Said network plates and heat exchanger plates are designed to have the option to be assembled as modules of larger processing units.

An example device with a microfluidic channel for use in a chamber is provided, the example device comprising: a chamber to contain a fluid; a microfluidic channel located internal to the chamber, the microfluidic channel having an entrance within the chamber and an exit within the chamber, the microfluidic channel defined by a housing located within the chamber; a unidirectional displacement mechanism inside the microfluidic channel, the unidirectional displacement mechanism located between the entrance and the exit; and a controller to activate the unidirectional displacement mechanism to cause the fluid from the chamber to enter the microfluidic channel via the entrance and leave the microfluidic channel via the exit thereby agitating the fluid within the chamber, the fluid otherwise being non-moving.

An example device with a microfluidic channel for use in a chamber is provided, the example device comprising: a chamber to contain a fluid; a microfluidic channel located internal to the chamber, the microfluidic channel having an entrance within the chamber and an exit within the chamber, the microfluidic channel defined by a housing located within the chamber; a unidirectional displacement mechanism inside the microfluidic channel, the unidirectional displacement mechanism located between the entrance and the exit; and a controller to activate the unidirectional displacement mechanism to cause the fluid from the chamber to enter the microfluidic channel via the entrance and leave the microfluidic channel via the exit thereby agitating the fluid within the chamber, the fluid otherwise being non-moving.