This disclosure relates to equipment utilized to manufacture chemical agents, particularly biopharmaceuticals. In some embodiments, reactor systems comprising a mobile carriage assembly; a disposable reaction container removably attached to the carriage assembly; and, a carriage holder into which the mobile carriage assembly may be removably inserted are provided.

A fluid mixing system includes a support housing having an interior surface bounding a chamber. A flexible bag is disposed within the chamber of the support housing, the flexible bag having an interior surface bounding a compartment. An impeller is disposed within the chamber of the flexible bag. A drive shaft is coupled with the impeller such that rotation of the drive shaft facilitates rotation of the impeller. A drive motor assembly is coupled with the draft shaft and is adapted to rotate the drive shaft. An adjustable arm assembly is coupled with the drive motor assembly and is adapted to move the drive motor assembly which in turn moves the position of the drive shaft and impeller. An electrical controller can control movement of the adjustable arm.

The presently disclosed subject matter relates to a system and method for customizing a cosmetic product. The system includes: an interface device, in electronic communication with a single batch cosmetic device. A container configured, to be imported into the single batch cosmetic device containing a base. The single batch cosmetic device configured to formulate a customized cosmetic product by mixing a cosmetic additive with the base inside the imported container using at least one mixing element. The container exported from the single batch cosmetic device containing the customized cosmetic.

A mixing and delivery system includes a compressible tube and a mixing apparatus. The compressible tube includes a reservoir configured for mixing and holding a surgical substance, an inlet portion for accommodating introduction of an element of the surgical substance into the compressible tube, and an exit port for enabling the delivery of the surgical substance to a target portion of an anatomy. The mixing apparatus is configured to be received through the inlet portion of the compressible tube for mixing elements of the surgical substance to form the surgical substance.

Apparatus that mixes non-homogenous fluid. A threaded shaft within a housing circulates fluid within a container to effect mixing. In one embodiment, when placed in a container of fluid, the housing the fluid is recirculated through opposing ends of the housing. In an embodiment of a related method for mixing, a pump housing containing a screw journaled for rotation receives fluid within a container and conveys the fluid therethrough to circulate a fluid portion in the container along an exterior surface of the housing for mixing with another fluid portion to improve fluid homogeneity. After mixing, the portion of the fluid which first circulates through the housing may recirculate through the housing with said another portion of the fluid. The fluid may be continuously mixed and recirculated through the housing.

A mixing machine includes a mixing head and at least one connection means for connecting a mixing container to the mixing head for forming a closed mixing container. The mixing head is pivotably mounted with respect to a frame such that the closed mixing container formed from the mixing head and container can be pivoted relative to the frame for performing the mixing process. The mixing head carries at least one rotationally-driven mixing tool. The mixing head comprises a head plate having a connecting flange molded thereon which is configured as an annular disc and comprises a planar contact surface. This contact surface has a radial extension such that mixing containers with different connection diameters on their mixing head connection side can be connected to the mixing head. The at least one connection means is configured for gripping mixing containers which differ in the diameter of their connection sides.

A mixer apparatus for mixing a high-viscosity fluid has a mixer shaft with a plurality of blades affixed thereto, a hydraulic motor drivingly connected to the mixer shaft so as to rotate the mixer shaft, a hydraulic pump connected by a fluid circuit to the hydraulic motor so as to deliver hydraulic fluid under pressure to the hydraulic motor, an electric motor drivingly connected to the hydraulic pump, and a hydraulic fluid reservoir connected to the fluid circuit so as to supply hydraulic fluid to the hydraulic pump. The plurality of blades are pivotally mounted to the mixer shaft.

A bioreactor may comprise a head-plate configured to provide coupling features to attach selected components to the bioreactor. The bioreactor may also comprise impeller and sparger, and the sparger is positioned at a pre-determined distance from the impeller based at least in part on a spatial configuration of the head-plate. The bioreactor further comprises a vessel defining a hollow enclosure for receiving a culture medium, and an opening of the vessel is covered by the head-plate.

A method for processing a fluid includes removably securing a retention member to a vessel that bounds a chamber; inserting a collapsible bag within the chamber of the vessel; securing the bag to the retention member so that the bag is supported within the chamber of the vessel; and dispensing a fluid into a compartment of the collapsible bag supported within the chamber of the vessel. The fluid can be mixed within bag while the bag is disposed within the vessel.

A fluid mixing system includes a support housing having an interior surface bounding a chamber. A flexible bag is disposed within the chamber of the support housing, the flexible bag having an interior surface bounding a compartment. An impeller is disposed within the chamber of the flexible bag. A drive shaft is coupled with the impeller such that rotation of the drive shaft facilitates rotation of the impeller. A drive motor assembly is coupled with the draft shaft and is adapted to rotate the drive shaft. An adjustable arm assembly is coupled with the drive motor assembly and is adapted to move the drive motor assembly which in turn moves the position of the drive shaft and impeller. An electrical controller can control movement of the adjustable arm.