A bubble generation device includes: a metallic narrow tube (10) through which water passes; and a pump that pressure-feeds the water containing a gas component into the metallic narrow tube (10). A drawer (11) in which a path through which the water passes is narrower than the front and the rear thereof in the flow direction of the water is disposed on the inside of the metallic narrow tube (10). The drawer (11) has the rectangular cross section orthogonal to the flow direction. The gas component contained in the water is dissolved in the water by pressure-feeding the water to the drawer (11), bubbles are evolved due to a decrease in pressure in the drawer (11), turbulent flow is generated in the water in the drawer (11) to crush bubbles in the water by the shearing force thereof, and bubbles are crushed by a shock wave caused by transonic flow occurring in the water that has exited from the drawer (11).

Method of performing a droplet-based assay. The method may include obtaining droplets encapsulated by an immiscible liquid and packed closely together in a monolayer, performing a reaction in the droplets while packed closely together in the monolayer; and collecting data related to an analyte from a plurality of the droplets while the droplets remain closely packed together in the monolayer.

An agitator device has at least one carrier unit, which has at least one connection element for a connection to a drive shaft and at least one beam element for the fastening of at least one agitator blade wherein the beam element and the connection element are connected to one another in a one-part implementation.

A size of an agitating mechanism can be reduced. An agitating mechanism according to an aspect of the present disclosure is an agitating mechanism for agitating fluid flowing through inside a pipe, including: a rotary body placed inside the pipe so as to be able to rotate in a circumferential direction of an inner circumferential surface of the pipe; and a regulation part configured to regulate a movement of the rotary body in a longitudinal direction of the pipe. The rotary body includes a hollow part penetrating the pipe in the longitudinal direction of the pipe and an agitating blade provided in the hollow part.

Methods of generating droplets. In an exemplary method, a device including a sample well, a carrier well, a droplet well, and a plurality of microfluidic channels is selected. The microfluidic channels include a first channel, a second channel, and a third channel. A discrete volume of sample-containing fluid is placed into the sample well, and a discrete volume of carrier fluid is placed into the carrier well. A pressure differential is created after placing the discrete volumes, to cause fluid flow. Sample-containing fluid flows from the sample well to a droplet-generation region of the device via the first channel. Carrier fluid flows from the carrier well to the droplet-generation region via the second channel. Sample-containing droplets and carrier fluid flow from the droplet-generation region to the droplet well via the third channel.

Devices and methods for generating droplets. An exemplary device comprises a substantially planar base portion including a bottom surface having a plurality of microfluidic channels formed therein as recessed regions of the bottom surface. The device also comprises a plurality of protrusions projecting from a top surface of the base portion and each formed integrally with the base portion. The device further comprises a sample well, a carrier well, and a droplet well. Each well has an upper portion created by one of the protrusions. A cover layer is attached to the bottom surface of the base portion and seals a bottom side of each microfluidic channel.

Methods of making a droplet-generating device. In an exemplary method, an upper member is injection molded. The upper member includes a bottom surface and also includes a first microfluidic channel, a second microfluidic channel, and a third microfluidic channel each formed in the bottom surface. The upper member has a plurality of openings each extending completely through the upper member from the bottom surface and creating a side wall region of a sample well, a carrier well, and a droplet well. A cover layer is attached to the bottom surface of the upper member, such that the cover layer seals a bottom side of each microfluidic channel. The microfluidic channels meet one another to create a droplet-generation region. The sample well, the carrier well, and the droplet well are connected to the droplet-generation region via the first, second, and third microfluidic channels, respectively.

A device for circulating wastewater is received in a tank, in which a conical or hyperboloid-like stirring body is mounted on a vertical stirring shaft, wherein the stirring body is composed from a plurality of segments produced from metal along radially extending joining zones.

The present invention relates to a device for coating and mixing granular products, in particular food products, more in particular peanuts, the device comprising a compartment defined by a rotary bottom part and a stationary circumferential side wall, the device further comprising: a product supply for supplying the products into the compartment, a substance supply for supplying a substance into the compartment, a drive for rotating the rotary bottom part about its substantially vertical axis, wherein the rotary bottom part and the stationary circumferential side wall comprise non-stick parts which define a substantial part of an inner surface of the compartment and which are manufactured from a non-stick material, wherein said non-stick parts are mechanically connected to the device via detachable connectors, allowing fast replacement of worn-out non-stick parts by new, same non-stick parts.

A stirring body has a hyperboloid-like or truncated cone-like form and a central connector piece for connection to a stirring shaft. To simplify the production of the stirring body and to reduce the transport outlay, it is proposed for the stirring body to be formed from a plurality of segments which are interconnected along joining zones extending from a peripheral edge in the direction of the connector piece.