Provided are methods and devices for dissolving solid protein compositions, such as solid compositions comprising fibrinogen, in an aqueous solvent. The methods comprise use of a closed container containing a volume of solid fibrinogen composition and a head space wherein the pressure within the headspace is sub-atmospheric. Aqueous solvent is introduced into the container while maintain the sub-atmospheric pressure, and subsequent to addition of the solvent, the size of the headspace is decreased to bring the pressure to atmospheric pressure. The devices are suitable for use in the disclosed method.

One embodiment relates to a device for the production of a bone cement dough from a monomer liquid and a cement powder comprising a cartridge with an internal space; a cartridge head with a dispensing opening; a conveying plunger that is arranged in the internal space of the cartridge and is supported in the internal space of the cartridge such that it is pushable in the direction of the dispensing opening; a dispensing plunger between the dispensing opening and the conveying plunger that is supported in the internal space of the cartridge such that it is pushable in the direction of the dispensing opening; a first hollow space, in which the cement powder is arranged; a second hollow space that is bordered by the dispensing plunger and the conveying plunger; a fluid opening that is arranged in the conveying plunger; a feedthrough that connects the first hollow space and the second hollow space to each other, and a closure means that is arranged on a rear side of the dispensing plunger. The closure means projects away from the dispensing plunger and is situated at a distance from the fluid opening. The fluid opening is closable with the closure means. The closure means is mobile in the closed fluid opening such that the fluid opening stays closed, while the conveying plunger is pushable further in the direction of the dispensing plunger.

The present invention relates to a dispenser for viscous materials that includes a static mixer, a first and second receptacle R.sub.1 and R.sub.2 for a first and second viscous material, connected in fluid communication with the static mixer, a first and second actuator configured for discharge of receptacle R.sub.1 and R.sub.2, an electrically or manually operable drive and a mechanical or hydraulic power transmission configured to translate drive motion into first and second actuator motion.

A system and method are presented for producing solder paste having undercooled metallic core-shell particles. In one or more arrangements, the system includes a reconstitution assembly, a dispenser assembly, and a mixer, among other components. The reconstitution assembly is configured to place the cores of the solid core metallic core-shell particles into an undercooled liquid state to form a plurality of undercooled metallic core-shell particles. The dispenser assembly is configured to dispense one or more of a set of available flux components. The mixer assembly is configured to mix the one or more of the set of flux components dispensed by the dispenser assembly with the plurality of undercooled metallic core-shell particles formed by the reconstitution assembly to form a solder paste.

The present disclosure generally relates to a reactor, in particular to a multiphase interface reactor applicable to chemistry, chemical industry, food, medicine, cosmetics and other fields. The reactor comprises a reaction cylinder; at least one feed port opened in the reaction cylinder; a stirring device, at least a part of the stirring device being located inside the reaction cylinder; at least one cylinder including a first cylinder and a second cylinder, wherein, the reaction cylinder, the first cylinder, and the second cylinder communicate with each other; an annular space is formed between the reaction cylinder and the second cylinder, so that at least part of a reaction product is allowed to enter the annular space from the reaction cylinder, and enter the first cylinder from the annular space; and at least one discharge port arranged on the first cylinder.

An apparatus to realize personalized cosmetic compositions including a formula supply assembly having a plurality of additive reservoirs that contains a plurality of additive substances, a plurality of additive pumps that supplies selected additive quantities of the plurality of additive substances, a base reservoir that contains a base substance, and a base pump that supplies a base quantity of the base substance and a mixing assembly having an additive inlet that receives the selected additive quantities, a base inlet that receives the base quantity, and a mixing channel that mixes the additive quantities with the base quantity to form the personalized cosmetic compositions.

A mixing apparatus for preparing mortar has a screw conveyor for conveying dry material, such as a mixture of sand and cement, from a storage vessel to a mixing chamber. The mixing chamber has an inlet end, adapted to receive dry material from an outlet end of the screw conveyor, an outlet end for dispensing wet mortar, and a water feed between the inlet and outlet ends for delivering a metered flow or quantity of water into the mixing chamber. A mixing device within the mixing chamber mixes the dry material and water and controls passage of material from the inlet to the outlet end. The outlet end is located above said inlet end so the dry material falls under gravity from the outlet end into the mixing chamber, maintaining separation between the dry material in the screw conveyor and the wet material in the mixing chamber.

A system provides building materials including a packaging, a lifting device and a mixing and conveying device. The packaging can be positioned by the lifting device via the mixing and conveying device in such a way that a total height of the system is less than 230 cm.

A flow distribution system for distributing and dividing the flows of at least two separate fluids, the distribution system comprising: a three-dimensional nested structure of at least two fluid transporting fractals comprising at least a first fluid transporting fractal and a second fluid transporting fractal, each fluid transporting fractal having a respective fluid inlet which bifurcates to a plurality of fluid outlets, each fluid transporting fractal being configured to facilitate a flow therethrough independent from a flow in the other fluid transporting fractal, each fluid transporting fractal extending along and about a central axis between fluid inlet and a plurality of fluid outlets; wherein each fluid transporting fractals comprises of a series of recursive bifurcation units assembled in a selected number of stages, each bifurcation unit comprising a Y-shaped bifurcated element which is fluidly connected to two successive bifurcation units, each successive bifurcation unit being rotated relative to the central axis by an angle of between 60 and 120 degrees relative to the previous stage; each fluid transporting fractal is intertwined with the other fluid transporting fractal; each fluid transporting fractal is positioned offset from the other fluid transporting fractal about the central axis and are arranged such that each fluid outlet from one of the fluid transporting fractals is located adjoining a fluid outlet of the other fluid transporting fractal, and each fluid transporting fractal is centered about a flow axis which is laterally inclined from greater than 0 to 20 degrees from the central axis and longitudinally inclined from greater than 0 to 20 degrees from the central axis.

This invention relates to a container (1) which is pre-filled or pre-fillable with one or more substances, such as a medical liquid and similar, comprising a squeezable activation compartment (2) intended to contain said one or more substances, a dispensing compartment (3) including a first portion (31) equipped with at least one dispensing member (311, 312, 314) of said one or more substances, and a second portion (32), wherein said second portion (32) of said dispensing compartment (3) and said activation compartment (2) are fluid-dynamically connected, and an activator element (4) arranged inside said container (1).

This invention also relates to a method for dispensing at least one substance by means of a container (1), and to a production method of a container (1).