The present invention relates to a mixing system for a bioreactor, comprising a plurality of supply units (10), each being able to hold media for use in a bioreactor a mixing unit (30) for creating a uniform mixing of media a first feeding mechanism (20), arranged to feed media from the supply units (10) into the mixing unit (30), a control unit (40) operatively connected to the first feeding mechanism (20) and the mixing unit (30), said control unit (40) being configured to control the first feeding mechanism (20) to feed predetermined amounts of media from the plurality of supply units (10) to the mixing unit (30), and further being configured to control the mixing unit (30) to create a uniform mixing of media. The invention also relates to a method for mixing media for use in a bioreactor.

Provided according to some embodiments of the invention are methods of manufacturing a pharmaceutical composition. In some embodiments, such methods include homogenizing at a first excipient composition that includes a viscosity agent and at least one solvent to form a first premix composition; separately homogenizing at least one active pharmaceutical ingredient (API) and a second excipient composition to form a second premix composition; and combining the first premix composition and the second premix composition to form the composition. The pre-mixing of constituents may increase the stability of the API and provide uniformity of the dispersion of the constituents throughout the final topical composition.

The present application is directed towards systems and methods for adding components to materials being fluidized in a vibratory mixer by use of atomizers or sprayers. A mechanical system can fluidizes, mix, coat, dry, combine, or segregate materials. The system may comprise a vibratory mixer, mixing vessel containing a first material and a sprayer to introduce a second material. The vibratory mixer may generate a fluidized bed of a first material and the sprayer, coupled to the mixing vessel, may introduce a second material onto the fluidized bed to mix the materials in a uniform and even fashion.

A device for cooling a slurry manufacturing mixer-comprises: a rotation container that comprises a mixing part, which mixes slurry and has a temperature detection part, and a slurry discharge part, which is formed under the mixing part and has a discharge hole for discharging the slurry; a body that is positioned under the rotation container and has a through-hole formed therethrough, through which the rotation container is inserted; and a sealing member interposed between the rotation container and the body, wherein the mixing part comprises an inner container and an outer container, and a cooling water passage is formed between the inner container and the outer container.

Provided is a UFB generating apparatus that is capable of efficiently generating a UFB-containing liquid with high purity by controlling generation of UFBs in the liquid. A UFB generating apparatus includes a driving unit that drives a heating element included in a heating unit to generate film boiling in the liquid in contact with the heating element, and a control unit that controls driving conditions of the heating element by the driving unit.

An indirect heating, drying and mixing chamber has a drum. A mixing/conveyor mechanism is positioned within the drum mixing and moving materials through the drum. An enclosure is provided wherein the drum is inserted within the enclosure to form an upper section of the enclosure between the drum and a top surface of the enclosure and a lower section of the enclosure between the drum and a bottom surface of the enclosure. A plurality of heat openings is formed on the bottom surface of the enclosure. A plurality of heating elements is provided, wherein an individual heating element is coupled to a corresponding heat opening, the plurality of heating elements generating heat which travels along the lower section of the enclosure and through the upper section of the enclosure heating the material in the drum.

An indirect heating, drying and mixing chamber has a drum. A mixing/conveyor mechanism is positioned within the drum mixing and moving materials through the drum. An enclosure is provided wherein the drum is inserted within the enclosure to form an upper section of the enclosure between the drum and a top surface of the enclosure and a lower section of the enclosure between the drum and a bottom surface of the enclosure. A plurality of heat openings is formed on the bottom surface of the enclosure. A plurality of heating elements is provided, wherein an individual heating element is coupled to a corresponding heat opening, the plurality of heating elements generating heat which travels along the lower section of the enclosure and through the upper section of the enclosure heating the material in the drum.

A battery paste mixer condensation assembly includes a duct, a condenser, a basin, and a pipe. The duct is in fluid communication with a battery paste mixer. Exiting gas from the battery paste mixer can travel through the duct. The condenser is situated downstream of the duct. The basin is situated near the condenser. Condensed liquid from the condenser is deposited in the basin. The pipe is in fluid communication with the basin and is in fluid communication with the battery paste mixer. Deposited liquid in the basin can travel from the basin and to the battery paste mixer by way of the pipe.

A battery paste mixer condensation assembly includes a duct, a condenser, a basin, and a pipe. The duct is in fluid communication with a battery paste mixer. Exiting gas from the battery paste mixer can travel through the duct. The condenser is situated downstream of the duct. The basin is situated near the condenser. Condensed liquid from the condenser is deposited in the basin. The pipe is in fluid communication with the basin and is in fluid communication with the battery paste mixer. Deposited liquid in the basin can travel from the basin and to the battery paste mixer by way of the pipe.

A bottle warming apparatus is disclosed that combines heating and agitating of a bottle and its contents in order to achieve even warming, as well as, mixing the contents of the bottle.