The disclosure relates to an extended-range spray applicator, and methods of making and use thereof, for dosing vaccines and/or probiotics to avian animals at a distance.

A multipurpose solution mixer and a use method thereof are provided. The multipurpose solution mixer includes a main control unit, a solution storage unit and a solution blending unit installed in a case; an operation display unit and a liquid outlet provided on the case; and an atomization humidifying unit connected with the liquid outlet, wherein the main control unit is electrically connected with other units; the operation display unit is a display screen with touch operation functions; the solution storage unit includes sealed bottles and infusion tubes; the solution blending unit includes micropumps infusion tubes and a blending chamber, the blending chamber is connected with the atomization humidifying unit via respective infusion tubes, and the operation display unit sends instructions to the main control unit to control the micropumps to extract solutions from the sealed bottles into the blending chamber, and output a mixed solution via the liquid outlet.

An NO-accumulation apparatus, method and use, comprising: a container (120) defining a cavity for accommodating a liquid (105), an inlet (150) for feeding the liquid into the container (120) and an outlet (151) for delivering the liquid from the container (120) to a bath unit; an NO-gas dissolving unit (140) for dissolving gaseous NO in the liquid (105) to produce an NO-containing liquid, wherein the NO-gas dissolving unit (140) is arranged in the container (120) and/or forms a part of the container (120); and an NO-gas port (110) in fluid communication with the NO-gas dissolving unit (140), wherein the NO-gas port (110) is adapted for coupling, particularly for releasably coupling, with an NO-gas supply, whereby the apparatus further comprises means for decoupling the inflow of NO to the liquid (105) within the container from the removal of the NO-containing liquid (NO-decoupling means), so that the removal of the NO-containing liquid is inhibited, when the NO is flowing into the liquid, and also the NO inflow is inhibited when the NO-containing liquid is removed from the container (105).

A syringe system for harvesting, mixing and emulsifying lipoaspirate and for further harvesting stromal vascular faction of adipose tissue. Stromal vascular faction contains mesenchymal stem cells, which have medically therapeutic uses. A mixing and/or emulsifying apparatus can be reciprocated in a syringe and combined with the stopper of the syringe, so that the syringe can be multi-purpose for harvesting, mixing, emulsifying, centrifuging, and transferring. This system minimizes transfers between syringes, allowing the system to remain closed and sterile.

A method and system are used to enhance a marker material to include a plurality of air bubbles. The method of manufacturing a marker includes enhancing a marker material to include a plurality of air bubbles using at least a first EFD and a second EFD. The method may include cycling repeatedly through a transfer process between a first container and a second container. A system for enhancing a marker material includes a transfer apparatus configured to receive a marker material and a selected amount of air. The system comprises a first EFD coupled to a first end of the transfer apparatus and a second EFD coupled to a second end of the transfer apparatus.

A system and apparatus for opening and emptying a bag of material includes a base having a pair of opposed sides and a central aperture through which material may flow. The system includes a pair of opposed doors rotatably mounted on a pair of door shafts, the edges of the pair of opposed doors forming an opening and a plurality of piercing blades pivotally mounted to the base on a pivot rod, the blades capable of pivoting to pierce said bag. The system further includes a cutting blade mounted transversely below the opening of the opposed doors, the cutting blade capable of linear motion across the opening.

A method of producing lipid-based micro/nano bubbles includes steps of (a) preparing a lipid mixture including one or more first lipids with different phase transition temperature, and a second lipid bonding with a hydrophilic polymer moiety or molecules capable of getting across a lipid membrane and decreasing van der Waals forces between lipid bilayers; (b) emulsifying the lipid mixture with a solvent, to form a transparent lipid carrier solution; (c) placing the transparent lipid carrier solution in a closed vessel with halo-substituted hydrocarbon; (d) manipulating temperature of the transparent lipid carrier solution to be close to a main phase transition temperature thereof; and (e) agitating in a mechanical manner the vessel containing the transparent lipid carrier solution to form micro/nano bubbles within the closed vessel. This method contributes to form micro/nano bubbles with desired diameters in a way of optimal material utilization efficiency.

Apparatus and systems are disclosed for improved set-up of multi-ingredient compounders. An improved apparatus includes a manifold and a plurality of valve members disposed for movement relative to different corresponding ones of a plurality of inlet ports of the manifold. The valve members are moveable to open and close a corresponding fluid passageway between the corresponding inlet port and an internal passageway of the manifold. A plurality of caps are locatable on different corresponding ones of the inlet ports, with each of the caps being engageable with the corresponding valve member for co-movement from a locked position at which the cap is restricted from removal to an unlocked position at which the cap is removable, e.g. by manual, axial retraction of the cap. An improved system includes a compounder controller operable to control valve actuators of the compounder so as to sequentially move the valve members and corresponding caps from locked to unlocked positions in a predetermined sequence, thereby reducing the potential for undesired cross-connections.

The invention concerns a gas mixer (1) comprising a first mixing vessel (42) and a second mixing vessel (52); a first line (22) for providing a first gas and a second line (32) for providing a second gas, the first and second lines (22, 32) being in fluid communication with the first mixing vessel (42) and with the second mixing vessel (52) for proving said first and second gases to said first and second mixing vessels (42, 52); and a third line (12) for providing a third gas, said third line (12) being in fluid communication with the second mixing vessel (52).

Dry thawing systems and devices for thawing biological substances are provided herein. Methods for thawing biological substances are also provided.