A system for mixing a sample with a combined buffer includes a sampler body, the sampler body including a first reservoir and a second reservoir. The system further includes a first separator forming a first enclosure with the sampler body for the first reservoir. The system further includes a second separator forming a second enclosure with the sampler body for the first reservoir. The system further includes a third separator, in conjunction with the second separator, forming a third enclosure and a fourth enclosure, respectively, both in conjunction with the sampler body, for the second reservoir.

An apparatus for mass producing monodisperse microbubbles contains a microfluidic flow focusing device. The microfluidic flow focusing device includes a dispersed phase fluid supply channel having an outlet that discharges into a flow focusing junction, a continuous phase fluid supply channel having an outlet that discharges into the flow focusing junction, and a bubble formation channel having an inlet disposed at the flow focusing junction. The configuration of the flow focusing junction is such that, in operation, a flow of dispersed phase fluid discharging from the outlet of the dispersed phase fluid supply channel is engageable in co-flow by a focusing flow of continuous phase fluid discharging from the outlet of the at least one continuous phase fluid supply channel under formation of a gradually thinning jet of dispersed phase fluid that extends into the inlet of the bubble formation channel.

A disposable container, such as a deformable bag, for a fluid, having one or more inlets and one or more outlets and an impeller assembly within the container to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The region within the container that can contain liquid is funnel shaped, which allows very low fluid level mixing, dispensing while mixing, and a reduction or elimination of vortex formation.

The present technology discloses a cost-effective, single use bag or container for storing biological substances that incorporates on its inner wall an electronic device that is configured to measure physiological and/or physical parameters of the enclosed biological substances, such as source history, identification, demographics, time stamping, temperature, pH, conductivity, glucose, O.sub.2, CO.sub.2 levels etc. The electronic device of the disclosed bag comprises a sensor configured to measure physiological and/or physical parameters of the biological substances enclosed within the bag, and a radio-frequency (RF) device communicably coupled to the sensor and configured to: (a) acquire from the sensor data associated with the measured parameters, (b) store the acquired sensor data in nonvolatile memory, and (c) communicate the stored data wirelessly to a RF reader.

The mixing system for ready-to-use flush solutions is characterized by an RO system, a mixing unit that is connected to the RO system and that contains a mixing chamber, to which high-purity water can be fed from the RO system and flush solution concentrate can be fed from a concentrate source, and a flush solution link connector, wherein the RO system and the mixing unit form a filling station, a mobile flush solution container that contains a pressurized container that receives a flush solution bag that can be coupled to the flush solution link connector of the mixing unit, and a computer and control mechanism for all measurement and monitoring tasks during the local production of a flush solution, wherein the mobile flush solution container and the filling station are provided with sensors by means of which wireless communication is made possible between the mobile flush solution container and the filling station.

A mini mixer system includes a mixer, for executing a continuous mixing operation for an extended period of time, the mixing operation includes a mixing production process with corrosiveness, high viscosity and high mixing risks. The mixer includes a motor, a coupling and torsion meter, a reduction gear, a plurality of couplings, a frame group, a gear box group, at least one mixing element, a mixing can and a lifting mechanism group. The motor, the coupling and torsion meter and the reduction gear are connected to one another by the couplings. The reduction gear is connected to the gear box group by the coupling. The motor, the reduction gear, the gear box group and the lifting mechanism group are all fixed on the frame group. The mixer is assembled in a gear mechanism of the gear box group. The mixing can is disposed on the lifting mechanism group.

A method of mixing a liquid composition that includes microparticles dispersed in an aqueous liquid carrier may involve a first premixing step and a second premixing step. During the first premixing step a receptacle is oscillated about a longitudinal axis clockwise and counter-clockwise from a first reference point through a first angle of rotation for a first period of time and at a first angular velocity. During the second premixing step the receptacle is oscillated about the longitudinal axis clockwise and counter-clockwise from a second reference point through a second angle of rotation for a second period of time and at a second angular velocity. In examples, the first angle of rotation is smaller than said second angle of rotation, and the first period of time is shorter than the second period of time.

A fluid mixing device is provided with a plurality of flow channel units disposed to be divided in a plurality of layers. Each of the flow channel units has an inflow port, an outflow port, and a plurality of branch flow channels making the inflow port and the outflow port communicate with each other. The flow channel units located in different layers are connected to each other at the inflow port and the outflow port between the flow channel units, thereby configuring a three-dimensional flow channel as a whole. When the direction from the inflow port to the outflow path of each flow channel unit is set to be a flow direction in the flow channel unit, the flow directions intersect each other between the respective layers.

A system for dispensing a biocompatible reactive formulation includes a first chamber containing a first fluid having a first reactive component, a second chamber containing a second fluid having a second reactive component, and a third chamber containing a third fluid. A spray tip assembly is configured for spraying a final mixture of the first, second and third fluids. The spray tip assembly has a spray tip housing, a mixing element disposed within the spray tip housing, a mixing chamber located between the mixing element and an inner surface of the spray tip housing. The mixing element has a proximal end adjacent the proximal end of the spray tip housing and a distal end adjacent the distal end of the spray tip housing, a third fluid inlet opening at the proximal end of the mixing element, and one or more third fluid exit openings formed in the outer surface of the mixing element that are in fluid communication with the third fluid inlet opening and that extend laterally to the outer surface of the mixing element for being in fluid communication with the mixing chamber. A fluid connector is secured to the proximal end of the spray tip housing and opposes the proximal end of the mixing element. The fluid connector has first and second fluid channels in fluid communication with the mixing chamber, and a third fluid channel in fluid communication with the third fluid inlet opening of the mixing element. A pump assembly is coupled with the first, second and third chambers for simultaneously forcing the first, second and third fluids to flow through the first, second and third fluid channels of the fluid connector and into the proximal end of the spray tip housing.

A disposable container, such as a deformable bag, for a fluid, having one or more inlets and one or more outlets and an impeller assembly within the container to cause mixing, dispersing, homogenizing and/or circulation of one or more ingredients contained or added to the container. The region within the container that can contain liquid is funnel shaped, which allows very low fluid level mixing, dispensing while mixing, and a reduction or elimination of vortex formation.